Patents by Inventor Philippe Dessen

Philippe Dessen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MOLECULAR IN VITRO DIAGNOSIS OF BREAST CANCER
    Publication number: 20120283132
    Abstract: A method for determining the benign or malignant state of a breast tumor in a biological sample is presented. The benign or malignant state is determined by measuring the variation of expression of twelve genes and at least one variant of each of the twelve genes when the variants exist, using a combination of 50 polynucleotide probe sets. An expression profile of the sample is then compared with reference expression profiles of control benign and malignant breast tissues. The probe sets can be arranged in a microarray.
    Type: Application
    Filed: July 17, 2012
    Publication date: November 8, 2012
    Applicants: INSTITUT GUSTAVE ROUSSY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Fabrice ANDRE, Stefan MICHIELS, Suzette DELALOGE, Marc SPIELMANN, Philippe DESSEN, Philippe VIELH
  • Molecular in vitro diagnosis of breast cancer
    Patent number: 8299233
    Abstract: The invention relates to the use of a multiplicity of polynucleotide probe sets, the multiplicity of polynucleotide probe sets consisting in a combination of pools of polynucleotide probe sets, each polynucleotide probe set containing at least one polynucleotide probe chosen among a library of nucleic acid sequences, the polynucleotide probes involved in the combination of pools of polynucleotide probe sets of the multiplicity of polynucleotide probe sets being such that each polynucleotide probe specifically hybridizes with one gene, and/or at least one of its variants when present, for determining the variation of expression at least 12 genes, and their variants when present, in order to diagnose the benign or malignant state of a breast tumor.
    Type: Grant
    Filed: January 5, 2009
    Date of Patent: October 30, 2012
    Assignees: Centre National de la Recherche Scientifique, Institut Gustave Roussy
    Inventors: Fabrice Andre, Stefan Michiels, Suzette Delaloge, Marc Spielmann, Philippe Dessen, Philippe Vielh
  • MOLECULAR IN VITRO DIAGNOSIS OF BREAST CANCER
    Publication number: 20110009286
    Abstract: The invention relates to the use of a multiplicity of polynucleotide probe sets, the multiplicity of polynucleotide probe sets consisting in a combination of pools of polynucleotide probe sets, each polynucleotide probe set containing at least one polynucleotide probe chosen among a library of nucleic acid sequences, the polynucleotide probes involved in the combination of pools of polynucleotide probe sets of the multiplicity of polynucleotide probe sets being such that each polynucleotide probe specifically hybridizes with one gene, and/or at least one of its variants when present, for determining the variation of expression at least 12 genes, and their variants when present, in order to diagnose the benign or malignant state of a breast tumor.
    Type: Application
    Filed: January 5, 2009
    Publication date: January 13, 2011
    Applicant: Centre National De La Recerche Scientifque
    Inventors: Fabrice Andre, Stefan Michiels, Suzette Delaloge, Marc Spielmann, Philippe Dessen, Philippe Vielh