Patents by Inventor Philippe Dijan

Philippe Dijan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Attaching agents to tissue with transglutaminase and a transglutaminase substrate
    Patent number: 6267957
    Abstract: Methods, products and kits are provided for attaching agents to tissue with a linking molecule in the presence of transglutaminase. The linking molecule and/or agent is a substrate of transglutaminase. The agent can be a nonprotein or an enzyme such as cholinesterase or phosphodiesterase. The transglutaminase may be exogenously added or be endogenous in tissue. In specific embodiments, the linking molecule contains at least two contiguous linked glutamines or at least three contiguous linked lysines. A conjugate of the agent and the linking molecule may be applied to tissue, and in the presence of transglutaminase covalently bonded to the tissue via the linking molecule. A complementary linking molecule rich in lysines may be first attached to the tissue in the presence of transglutaminase, and then covalently bonded to a glutamine-containing linking molecule of the conjugate in the presence of transglutaminase.
    Type: Grant
    Filed: January 20, 1999
    Date of Patent: July 31, 2001
    Inventors: Howard Green, George D. Corey, Bruce J. Compton, Philippe Dijan
  • Cosmetic containing comeocyte proteins and transglutaminase, and method of application
    Patent number: 5525336
    Abstract: A cosmetic composition comprising corneocyte proteins and transglutaminase in a cosmetically acceptable vehicle is provided. Upon application, the ingredients of the cosmetic cross link with the outer layer of skin, hair or nails to form a protective layer on the skin, hair or nails.
    Type: Grant
    Filed: May 18, 1994
    Date of Patent: June 11, 1996
    Inventors: Howard Green, Philippe Dijan