Patents by Inventor Philippe Fretier

Philippe Fretier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antioxidants, preparation methods and uses
    Patent number: 6989372
    Abstract: The invention concerns compounds of general formula (I) (wherein R and R? represent an alkyl radical or an aryl group and R? is hydrogen or a CO—R1 group wherein R1 is an alkyl radical or an aryl group; and the dimers formed by the disulphide bond from one and/or the other of the two sulphur atoms of the compounds of general formula (I); and the corresponding thiazolidin forms), the methods for preparing them and uses thereof. More particularly, it concerns the use of said compounds as antioxidant agents, in particular for preparing medicines designed to increase the intracellular and/or extracellular level of glutathione (GSH).
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: January 24, 2006
    Assignees: Centre National de la Recherche Scientifique (CNRS), Commissariat a l'Engergie Atomique
    Inventors: Joël Oiry, Jean-Yves Puy, Jean-Louis Imbach, Pascal Clayette, Philippe Fretier
  • Antioxidants, preparation processes and their uses
    Patent number: 6979747
    Abstract: The invention concerns a process for preparing compounds of general formula (I) wherein R and R? represent an alkyl radical or an aryl group; and R? is hydrogen or a CO—R1 group wherein R1 is an alkyl radical or an aryl group; and wherein these compounds are or not in the thiazolidine form; by protecting the N-acyl-L-cysteine to form an intermediate compound; and then by coupling said intermediate compound with S-acylcysteamine hydrochloride or with thiazolidine.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: December 27, 2005
    Assignees: Centre National de la Recherche Scientifique (CNRS), Commissariat A L'Energie Atomique
    Inventors: Joel Oiry, Jean-Yves Puy, Jean-Louis Imbach, Pascal Clayette, Philippe Fretier
  • Novel antioxidants, preparation processes and their uses
    Publication number: 20040158092
    Abstract: The invention concerns a process for preparing compounds of general formula (I) 1
    Type: Application
    Filed: December 16, 2003
    Publication date: August 12, 2004
    Inventors: Joel Oiry, Jean-Yves Puy, Jean-Louis Imbach, Pascal Clayette, Philippe Fretier