Patents by Inventor Philippe Gain

Philippe Gain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11974569
    Abstract: The present invention relates to a device for holding human or animal corneal tissue previously removed for photon treatment thereof with electromagnetic radiation, notable in that the holding device comprises: a stack of elements along a longitudinal axis (A-A?) of the device, said stack comprising: a first plate (1) that is transparent to the electromagnetic radiation, a peripheral seal (4) positioned on the first plate (1), the peripheral seal (4) being intended to extend around the corneal tissue (6), a second plate (2) that is transparent to the electromagnetic radiation on the peripheral seal (4), an immobilizing system (51, 52) for immobilizing the stack of elements and able to press the first and second plates (1, 2) firmly against the corneal tissue in order to apply mechanical stress to the anterior and posterior faces of the corneal tissue.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: May 7, 2024
    Assignees: UNIVERSITE JEAN MONNET, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER UNIVERSITAIRE, MANUTECH-USD
    Inventors: Philippe Gain, Gilles Thuret, Cyril Mauclair, Clotilde Jumelle, Gregory Egaud
  • Publication number: 20220257418
    Abstract: A device for cutting human or animal tissue including a femtosecond laser that can emit a L.A.S.E.R. beam in the form of impulses. The device directs and focuses the beam onto or into the tissue for the cutting thereof. The device further includes and element to shape the L.A.S.E.R. beam, positioned in the trajectory of the beam, and to modulate the energy distribution of the L.A.S.E.R. beam in the focal plane thereof, corresponding to the cutting plane.
    Type: Application
    Filed: May 3, 2022
    Publication date: August 18, 2022
    Inventors: Aurelien BERNARD, Philippe GAIN, Cyril MAUCLAIR, Gilles THURET
  • Publication number: 20220249222
    Abstract: The invention concerns a cutting process for producing a plurality of implants from a previously removed human or animal cornea, wherein the process comprises the following steps: depositing (200) the cornea in a holding device, cutting (300), using a laser source, the cornea contained in the holding device to obtain a cut cornea, detaching (400) each implant from the cut cornea, decellularizing (500) each detached implant to obtain decellularized implants, lyophilizing (600) each decellularized implant to obtain lyophilized implants, sterilizing (700) each lyophilized implant to obtain sterilized implants, packaging (800) each sterilized implant to obtain packaged implants.
    Type: Application
    Filed: July 22, 2020
    Publication date: August 11, 2022
    Inventors: Philippe GAIN, Gilles THURET, Cyril MAUCLAIR, Samy ALBOURGOL, Gregory EGAUD
  • Publication number: 20220241463
    Abstract: The invention concerns a process for preparing an allograft or xenograft material from a lens capsule, wherein the process comprises the following steps: Decellularizing (200) a lens capsule to obtain a decellularized lens capsule, Depositing (300) the decellularized capsule on a microporous support membrane to obtain a stack composed of the decellularized lens capsule and the support membrane, Lyophilizing (400) the stack to obtain a lyophilized stack, Sterilizing (500) the lyophilized stack to obtain a sterilized stack, Packaging (600) the sterilized stack to obtain allograft or xenograft materials.
    Type: Application
    Filed: July 22, 2020
    Publication date: August 4, 2022
    Inventors: Philippe GAIN, Gilles THURET, Zhiguo HE
  • Patent number: 11351062
    Abstract: A device for cutting human or animal tissue including a femtosecond laser that can emit a L.A.S.E.R. beam in the form of impulses. The device directs and focuses the beam onto or into the tissue for the cutting thereof. The device further includes and element to shape the L.A.S.E.R. beam, positioned in the trajectory of the beam, and to modulate the energy distribution of the L.A.S.E.R. beam in the focal plane thereof, corresponding to the cutting plane.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: June 7, 2022
    Assignees: UNIVERSITE JEAN MONNET SAINT ETIENNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Aurelien Bernard, Philippe Gain, Cyril Mauclair, Gilles Thuret
  • Patent number: 11229202
    Abstract: The invention relates to a medical device in the form of a cartridge (2) incorporating an assembly permitting the preservation of corneal tissue that has been obtained beforehand by sampling, the device comprising: a storage compartment (24) containing a preserving fluid, at least one input terminal (21) upstream from the storage compartment (24), for injecting a compressed pressurizing gas, at least one control terminal (22) upstream from the storage compartment (24), for injecting a compressed control gas, a pneumatically controlled switching system (26) downstream from the terminals (21, 22), said switching system (26) being controlled by the compressed control gas in order to permit or prohibit the circulation of the compressed pressurizing gas towards the storage compartment (24).
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: January 25, 2022
    Assignees: UNIVERSITE JEAN MONNET, CENTRE HOSPITALIER UNIVERSITAIRE
    Inventors: Philippe Gain, Gilles Thuret, Pascal Herbepin
  • Patent number: 11229201
    Abstract: The invention relates to a medical device for preservation of corneal tissue (3) that has been obtained beforehand by sampling, the device comprising a base (11), at least one side wall (12), and means for receiving and blocking the corneal tissue (3), characterized in that the device additionally comprises an applanation lid (13) for covering an opening of the device opposite the transparent base (11), the applanation lid (13) comprising: a transparent window (131), and a support (132) between the window (131) and the side wall (12), the support (132) comprising means for moving the window (131) in translation with respect to the side wall (12) of the device.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: January 25, 2022
    Assignees: UNIVERSITE JEAN MONNET, CENTRE HOSPITALIER UNIVERSITAIRE
    Inventors: Philippe Gain, Gilles Thuret, Pascal Herbepin
  • Publication number: 20210321607
    Abstract: The present invention relates to a device for holding human or animal corneal tissue previously removed for photon treatment thereof with electromagnetic radiation, notable in that the holding device comprises: a stack of elements along a longitudinal axis (A-A?) of the device, said stack comprising: a first plate (1) that is transparent to the electromagnetic radiation, a peripheral seal (4) positioned on the first plate (1), the peripheral seal (4) being intended to extend around the corneal tissue (6), a second plate (2) that is transparent to the electromagnetic radiation on the peripheral seal (4), an immobilizing system (51, 52) for immobilizing the stack of elements and able to press the first and second plates (1, 2) firmly against the corneal tissue in order to apply mechanical stress to the anterior and posterior faces of the corneal tissue.
    Type: Application
    Filed: July 17, 2019
    Publication date: October 21, 2021
    Inventors: Philippe GAIN, Gilles THURET, Cyril MAUCLAIR, Clotilde JUMELLE, Gregory EGAUD
  • Publication number: 20210084892
    Abstract: The invention relates to a medical device for preservation of corneal tissue (3) that has been obtained beforehand by sampling, the device comprising a base (11), at least one side wall (12), and means for receiving and blocking the corneal tissue (3), characterized in that the device additionally comprises an applanation lid (13) for covering an opening of the device opposite the transparent base (11), the applanation lid (13) comprising: a transparent window (131), and a support (132) between the window (131) and the side wall (12), the support (132) comprising means for moving the window (131) in translation with respect to the side wall (12) of the device.
    Type: Application
    Filed: December 14, 2018
    Publication date: March 25, 2021
    Inventors: Philippe GAIN, Gilles THURET, Pascal HERBEPIN
  • Publication number: 20210076667
    Abstract: The invention relates to a medical device in the form of a cartridge (2) incorporating an assembly permitting the preservation of corneal tissue that has been obtained beforehand by sampling, the device comprising: a storage compartment (24) containing a preserving fluid, at least one input terminal (21) upstream from the storage compartment (24), for injecting a compressed pressurizing gas, at least one control terminal (22) upstream from the storage compartment (24), for injecting a compressed control gas, a pneumatically controlled switching system (26) downstream from the terminals (21, 22), said switching system (26) being controlled by the compressed control gas in order to permit or prohibit the circulation of the compressed pressurizing gas towards the storage compartment (24).
    Type: Application
    Filed: December 14, 2018
    Publication date: March 18, 2021
    Inventors: Philippe GAIN, Gilles THURET, Pascal HERBEPIN
  • Patent number: 10188097
    Abstract: A device for the storage of a corneal specimen has means for the reception and entrapment of a corneal specimen, connected to the means for the creation of a pressure gradient with overpressure on the endothelial side and to the preservation medium circulation means in the layouts that present the means for the reception and entrapment of the cornea specimen. The means for the reception and entrapment of the corneal specimen entrap the sclera ciliary zone surrounding the cornea in an airtight manner to delimit a separate endothelial chamber and epithelial chamber in which the preservation medium can circulate with an overpressure in the endothelial chamber; The intermediate component and the endothelial lid comprise inlet and outlet orifices for the preservation medium which are connected to the means for the circulation of the preservation medium and the creation of a pressure gradient between the endothelial chamber and the epithelial chamber with overpressure in the endothelial chamber.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: January 29, 2019
    Assignees: UNIVERSITE JEAN MONNET, ECOLE NATIONALE D'INGENIEURS DE SAINT-ETIENNE, ETABLISSEMENT FRANCAIS DU SANG
    Inventors: Philippe Gain, Gilles Thuret, Sophie Laverne-Acquart, Sébastien Soubaigne
  • Publication number: 20170304118
    Abstract: The invention relates to a device (1) for cutting human or animal tissue, such as a cornea (3), or a crystalline lens, said device comprising a femtosecond laser (2) that can emit a L.A.S.E.R. beam (4) in the form of impulses, and means for directing and focusing said beam onto or into the tissue for the cutting thereof as such. According to the invention, the device comprises means (9) for shaping the L.A.S.E.R. beam (4), which are positioned in the trajectory of said beam, and can modulate the energy distribution of the L.A.S.E.R. beam (4) in the focal plane thereof, corresponding to the cutting plane.
    Type: Application
    Filed: October 7, 2015
    Publication date: October 26, 2017
    Inventors: Aurelien BERNARD, Philippe GAIN, Cyril MAUCLAIR, Gilles THURET
  • Publication number: 20160029618
    Abstract: A device for the storage of a corneal specimen has means for the reception and entrapment of a corneal specimen, connected to the means for the creation of a pressure gradient with overpressure on the endothelial side and to the preservation medium circulation means in the layouts that present the means for the reception and entrapment of the cornea specimen. The means for the reception and entrapment of the corneal specimen entrap the sclera ciliary zone surrounding the cornea in an airtight manner to delimit a separate endothelial chamber and epithelial chamber in which the preservation medium can circulate with an overpressure in the endothelial chamber; The intermediate component and the endothelial lid comprise inlet and outlet orifices for the preservation medium which are connected to the means for the circulation of the preservation medium and the creation of a pressure gradient between the endothelial chamber and the epithelial chamber with overpressure in the endothelial chamber.
    Type: Application
    Filed: March 14, 2013
    Publication date: February 4, 2016
    Inventors: Philippe Gain, Gilles Thuret, Sophie Laverne-Acquart, Sébastien Soubaigne