Patents by Inventor Philippe Gripon

Philippe Gripon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis B virus pre-S1 derived synthetic polypeptides and uses thereof
    Patent number: 10323068
    Abstract: The invention relates to a group of synthetic polypeptides, derived from the pre-S1 region of HBV, that efficiently interfere with early steps of an HBV infection. The peptides of the invention can be used in diagnostics for the detection of antigens and/or antibodies.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: June 18, 2019
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Philippe Gripon, Stephan Urban
  • HEPATITIS B VIRUS PRE-S1 DERIVED SYNTHETIC POLYPEPTIDES AND USES THEREOF
    Publication number: 20160130307
    Abstract: The invention relates to a group of synthetic polypeptides, derived from the pre-S1 region of HBV, that efficiently interfere with early steps of an HBV infection. The peptides of the invention can be used in diagnostics for the detection of antigens and/or antibodies.
    Type: Application
    Filed: November 18, 2015
    Publication date: May 12, 2016
    Inventors: Philippe Gripon, Stephan Urban
  • HEPATITIS B VIRUS PRE-S1 DERIVED SYNTHETIC POLYPEPTIDES AND USES THEREOF
    Publication number: 20120329706
    Abstract: The invention relates to a group of synthetic polypeptides, derived from the pre-S1 region of HBV, that efficiently interfere with early steps of an HBV infection. The peptides of the invention can be used in diagnostics for the detection of antigens and/or antibodies.
    Type: Application
    Filed: August 9, 2012
    Publication date: December 27, 2012
    Inventors: Philippe GRIPON, Stephan Urban
  • HEPATITIS B VIRUS PRE-S1 DERIVED SYNTHETIC POLYPEPTIDES AND USES THEREOF
    Publication number: 20110178004
    Abstract: The invention relates to a group of synthetic polypeptides, derived from the pre-S1 region of HBV, that efficiently interfere with early steps of an HBV infection. The peptides of the invention can be used in diagnostics for the detection of antigens and/or antibodies.
    Type: Application
    Filed: January 26, 2011
    Publication date: July 21, 2011
    Inventors: Philippe GRIPON, Stephan Urban
  • Hepatitis B virus pre-S1 derived synthetic polypeptides and uses thereof
    Patent number: 7892754
    Abstract: The invention relates to a group of synthetic polypeptides, derived from the pre-S1 region of HBV, that efficiently interfere with early steps of an HBV infection. The peptides of the invention can be used in diagnostics for the detection of antigens and/or antibodies.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: February 22, 2011
    Assignees: Institut National de la Sante Et de la Recherche Medicale (INSERM)
    Inventors: Philippe Gripon, Stephan Urban
  • Human hepatoma lines, methods for obtaining same and uses thereof
    Patent number: 7456018
    Abstract: Human hepatoma cell lines are provided that comprises a set of cells clonally derived from a cancerous human liver cell, in which each cell of the set expresses a receptor having an affinity for binding a virus of the Flaviviridae genus and a virus of the Hepadnaviridae genus to enable infection by viruses of both genus in native forms, and in which each cell of the set exhibits susceptibility to infection by a hepatotropic parasite of the Leishmania genus in a native form. Various compositions and methods relating to diagnostic, therapeutic, and prophylactic embodiments are also provided.
    Type: Grant
    Filed: July 8, 2002
    Date of Patent: November 25, 2008
    Inventors: Philippe Gripon, Christiane Guguen-Guillouzo, Christian Trepo, Sylvie Rumin
  • Hepatitis B virus pre-S1 derived synthetic polypeptides and uses thereof
    Publication number: 20070116721
    Abstract: The invention relates to a group of synthetic polypeptides, derived from the pre-S 1 region of HBV, that efficiently interfere with early steps of an HBV infection. The peptides of the invention can be used in diagnostics for the detection of antigens and/or antibodies.
    Type: Application
    Filed: December 19, 2006
    Publication date: May 24, 2007
    Inventors: Philippe Gripon, Stephan Urban
  • Novel human hepatoma lines, methods for obtaining same and uses thereof
    Publication number: 20050064594
    Abstract: The invention concerns human hepatoma cell lines, characterized in that they are capable of being naturally infected by parasites and/or viruses; said parasites can be hepatotropic or not, such as Plasmodium or parasites of the genus leishmania and express receptors of the family of Flaviviridae and Ilepadnaviridae viruses, preferably HBV and HCV. The invention has diagnostic, therapeutic and prophylactic applications.
    Type: Application
    Filed: July 8, 2002
    Publication date: March 24, 2005
    Inventors: Philippe Gripon, Christiane Guguen-Guillouzo, Christian Trepo, Sylvie Rumin
  • Hepatitis b virus pre-s1 derived synthetic polypeptides and uses thereof
    Publication number: 20050053914
    Abstract: This invention relates to a group of synthetic polypeptides, derived from the pre-S1 region of HBV, that efficiently interferes with early steps of an HBV infection. The peptides of the invention can be used in diagnostics for the detection of antigens and/or antibodies.
    Type: Application
    Filed: July 26, 2002
    Publication date: March 10, 2005
    Inventors: Philippe Gripon, Stephan Urban