Patents by Inventor Philippe Hantraye

Philippe Hantraye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alzheimer's disease animal model
    Patent number: 10986821
    Abstract: The present invention relates to a vector comprising a nucleic acid sequence that encodes the APP protein and/or the PS1 protein or variants thereof. The invention also relates to a method for inducing the Alzheimer's disease in an animal using the vector of the invention and to animal model having the Alzheimer's disease obtained by said method.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: April 27, 2021
    Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Université de Paris—Sud, Commissariat a l'Energie Atomique et aux Energies Alternatives, Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes
    Inventors: Nathalie Cartier-Lacave, Jerome Braudeau, Nicole Deglon, Philippe Hantraye, Mickael Audrain
  • NEW ALZHEIMER'S DISEASE ANIMAL MODEL
    Publication number: 20190183102
    Abstract: The present invention relates to a vector comprising a nucleic acid sequence that encodes the APP protein and/or the PS1 protein or variants thereof. The invention also relates to a method for inducing the Alzheimer's disease in an animal using the vector of the invention and to animal model having the Alzheimer's disease obtained by said method.
    Type: Application
    Filed: November 2, 2018
    Publication date: June 20, 2019
    Inventors: Nathalie Cartier-Lacave, Jerome Braudeau, Nicole Deglon, Philippe Hantraye, Mickael Audrain
  • Alzheimer's disease animal model
    Patent number: 10159227
    Abstract: The present invention relates to a vector comprising a nucleic acid sequence that encodes the APP protein and/or the PS1 protein or variants thereof. The invention also relates to a method for inducing the Alzheimer's disease in an animal using the vector of the invention and to animal model having the Alzheimer's disease obtained by said method.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: December 25, 2018
    Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Universite de Paris—Sud, Commissariat a l'Energie Atomique et aux Energies Alternatives, Centre National de la Recherche Scientifique (CNRS), Universite Paris Descartes
    Inventors: Nathalie Cartier-Lacave, Jerome Braudeau, Nicole Deglon, Philippe Hantraye, Mickael Audrain
  • USE OF 7-CHLORO-N,N,5-TRIMETHYL-4-OXO-3-PHENYL-3,5-DIHYDRO-4H-PYRIDAZINO[4,5-B] INDOLE-1-ACETAMIDE AS A BIOMARKER OF PERIPHERAL BENZODIAZEPINE RECEPTOR LEVELS
    Publication number: 20170160287
    Abstract: Use of a radiolabelled form of 7-chloro-?/?,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4/?/?pyridazino[4,5-b]indole-1-acetamide as a biomarker for the detection, in an individual, of PBR levels associated with normal and pathological conditions. Method for the detection of PBR levels associated with normal and pathological conditions. Diagnostic kit.
    Type: Application
    Filed: November 10, 2016
    Publication date: June 8, 2017
    Inventors: Jesus BENAVIDES, Hérve BOUTIN, Marie-Noëlle CASTEL, Annelaure DAMONT, Frédéric DOLLE, Philippe HANTRAYE, Frank MARGUET, Thomas ROONEY, Luc RIVRON, Bertrand TAVITIAN, Cyrille THOMINIAUX
  • NEW ALZHEIMER'S DISEASE ANIMAL MODEL
    Publication number: 20160262361
    Abstract: The present invention relates to a vector comprising a nucleic acid sequence that encodes the APP protein and/or the PS1 protein or variants thereof. The invention also relates to a method for inducing the Alzheimer's disease in an animal using the vector of the invention and to animal model having the Alzheimer's disease obtained by said method.
    Type: Application
    Filed: November 5, 2014
    Publication date: September 15, 2016
    Inventors: Nathalie Cartier-Lacave, Jerome Braudeau, Nicole Deglon, Philippe Hantraye, Mickael Audrain
  • USE OF 7-CHLORO-N,N,5-TRIMETHYL-4-OXO-3-PHENYL-3,5-DIHYDRO-4H-PYRIDAZINO[4,5-B] INDOLE-1-ACETAMIDE AS A BIOMARKER OF PERIPHERAL BENZODIAZEPINE RECEPTOR LEVELS
    Publication number: 20120039816
    Abstract: Use of a radiolabelled form of 7-chloro-?/,?/,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4/-/-pyridazino[4,5-b]indole-1-acetamide as a biomarker for the detection, in an individual, of PBR levels associated with normal and pathological conditions. Method for the detection of PBR levels associated with normal and pathological conditions. Diagnostic kit.
    Type: Application
    Filed: October 27, 2009
    Publication date: February 16, 2012
    Applicants: SANOFI-AVENTIS, COMMISSARIAT A L'ENERGIE ATOMIQUE
    Inventors: Jesus Benavides, Hérve Boutin, Marie-Noëlle Castel, Annelaure Damont, Frédéric Dolle, Philippe Hantraye, Frank Marguet, Thomas Rooney, Luc Rivron, Bertrand Tavitian, Cyrille Thominiaux