Patents by Inventor Philippe J. Sansonetti

Philippe J. Sansonetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for screening for inhibitors and activators of type III secretion machinery in gram-negative bacteria
    Patent number: 6136542
    Abstract: This invention relates to mutant strains of gram-negative bacteria that constitutively secrete proteins via the type III secretion machinery. It also relates to methods of identifying molecules that are able to activate or inhibit secretion in wild-type strains of gram-negative bacteria by exposing gram-negative bacterial cells to a sample molecule, wherein said bacterial cells contain a reporter gene transcriptionally fused to a promoter of a gene activated or regulated by the type III secretion machinery, and detecting the presence or activity of the product of the reporter gene.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: October 24, 2000
    Assignees: Institut Pasteur, Institut Nationale de la Sante et de la Recherche
    Inventors: Brigitte Demers, Philippe J. Sansonetti, Claude Parsot