Abstract: A multiple viewpoint endoscope system having a multiple viewpoint camera setup and/or an intelligent or cognitive image control system and display device particularly adapted for localizing internal structures within a cavity or an enclosing structure, such as an animal body, for instance the abdomen of an animal or human, or for localizing a real or synthetic image of such internal structures within an overview image or on an overview 3D model.

Abstract: By present invention it has been found that hypothermia decreases adhesion formation more specifically pneumoperitoneum-enhanced adhesion formation. A cooling system has been designed to reduce the peritoneal cavity temperature during surgery, while maintaining at all times a 100% relative humidity in order to prevent desiccation, and a regulatory unit designed to condition the insufflated gas to achieve this while minimalising the necessary cooling. This is a new method for more effectively preventing adhesion though cooling while preventing desiccation. In mice it was demonstrated that factors such as environmental temperature, anaesthesia, ventilation and pneumoperitoneum can be used to influence body temperature in order to prevent adhesion formation.

Abstract: The present invention relates to a novel endoscope or an optical large view endoscopic system with improved depth perception. In particular, a multiple viewpoint endoscope system comprising a multiple viewpoint camera setup and/or an intelligent or cognitive image control system and display device particularly adapted for localising internal structures within a cavity or an enclosing structure, such as an animal body, for instance the abdomen of an animal or human, or for localising a real or synthetic image of such internal structures within an overview image or on an overview 3D model.

Abstract: By present invention it has been found that hypothermia decreases adhesion formation more specifically pneumoperitoneum-enhanced adhesion formation. A cooling system has been designed to reduce the peritoneal cavity temperature during surgery, while maintaining at all times a 100% relative humidity in order to prevent desiccation, and a regulatory unit designed to condition the insufflated gas to achieve this while minimalising the necessary cooling. This is a new method for more effectively preventing adhesion though cooling while preventing desiccation. In mice it was demonstrated that factors such as environmental temperature, anaesthesia, ventilation and pneumoperitoneum can be used to influence body temperature in order to prevent adhesion formation.

Abstract: The present invention is concerned with compositions for use in the medical art. More particularly the invention relates to uses of inhibitors against hypoxia-induced genes for the manufacture of a medicament to prevent and/or to suppress post-operative/post-wounding adhesions formation. Post-operative adhesions are an unwanted result from surgery and are a major source of postoperative morbidity and mortality. The invention applies to human and veterinary applications. To date, no single therapeutic approach has proven universally effective in preventing formation of post-operative adhesions formations.

Abstract: The invention relates to a device for reproducing an image of a poorly accessible location, for example in a living body, comprising a substantially cylindrical image pick-up unit to be arranged at the location and an image display means connected to the image pick-up unit, wherein the image pick-up unit is provided with indication means for indicating the rotation position of the image pick-up unit on its axis relative to the horizontal. As a result of these steps it is possible to give an indication of the horizontal, or for example the vertical, on the image reproduced on the image display means, so that the orientation of the displayed image is known, or by processing the displayed image or by turning the image display means such that the orientation of the displayed image corresponds with the actual orientation. Dangerous situations, for instance during performance of an operation, can herewith be avoided.

Abstract: An apparatus is provided for insufflating gas into a bodily cavity of a human or animal body. The apparatus includes a gas source, a measuring device provided with sensors for sensing the actual gas pressure and the actual gas flow, and a control unit to which the output signals of the sensors are applied. The control unit triggers a pressure regulator, which reduces and regulates the pressure of the gas source to an adjustable insufflation pressure (desired gas pressure), and a flow regulator, which regulates the gas flow to an adjustable value (desired gas flow). For measuring the actual gas pressure, the control unit triggers the flow regulator in such a manner that the gas flow is set at a value between 10 and 40% of the desired gas flow during pressure measurement.

Abstract: An insufflation system which provides continuous insufflation at a pre-set, limited low insufflation gas pressure and a high insufflation gas flow, thereby avoiding the necessity of measuring the intra-abdominal pressure while insuring that a determined pre-adjustable maximum insufflation gas pressure cannot be exceeded. The system comprises a gas delivery line having an inlet end coupled to a source of insufflation gas and an outlet end for connecting to the gas inlet of a surgical laser-equipped endoscope. A pressure adjustment device is connected into the gas delivery line for establishing a maximum insufflation gas flow pressure in the gas delivery line, and a gas exhaust tube that can be introduced into the body cavity provides for exhausting of insufflation gas delivered to the body cavity solely by the gas delivery line via the endoscope.