Abstract: The present invention refers to a system and method for opening a concentrate container without the need for a human to directly handle the concentrate container and connecting the concentrate container to a blood treatment device. Aspects of the invention are directed to a container for concentrate and a blood treatment device.

Abstract: A system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, a container and blood treatment device useful with the system and method are also provided.

Abstract: A bag is provided that is made of a flexible wall. The bag is fitted with an inlet fluid line for introducing dissolution water, and with an outlet fluid line for extracting a solution obtained. The inside of the bag has a lower edge in the overall shape of a V and the point of the V is further away from the center of the bag than are the arms of the V. The outlet fluid line opens into the bag as close as possible to the point of the V.

Abstract: The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.

Abstract: The invention relates to a bag (1) made of a flexible wall, which bag is fitted with an inlet fluid line for introducing dissolution water, and with an outlet fluid line (121, 122) for extracting a solution obtained. According to the invention, the inside of the bag has a lower edge (13) in the overall shape of a V, the point of the V being further away from the centre of the bag than the arms of the V, the outlet fluid line opening into the bag as close as possible to the point of the V.

Abstract: The present invention relates to a closing element for a fluid line, preferably a fluid line of a concentrate container, comprising a main body configured to at least partially receive the fluid line, a closing portion configured to be arranged on an open portion of the fluid line to close the fluid line, wherein the closing portion comprises a plurality of plates arranged around a common center point and each separated from another over an intended breaking point, an a pressure receiving portion configured to receive pressure applied by a pressure exertion element, preferably a connector element to be fluidically connected to the fluid line by breaking the intended breaking point, wherein the pressure receiving portion is formed by that part of the plurality of plates projecting outwards from the closing portion or the main body.

Abstract: The invention relates to a method for manufacturing a liquid acid concentrate for hemodialysis machines, with the following steps. In a preliminary step a water source (120), an acid source (130), an electrolyte tank (140) containing a mixture of electrolytes in exactly the quantity needed for the manufacture of the liquid acid concentrate, and a sodium chloride source (150) are connected to a mixing tank (110). During Step a), the quantity of water needed for the manufacture of the batch of liquid acid concentrate is introduced into the mixing tank (110). At Step b), the quantity of acid needed for manufacture the liquid acid concentrate is introduced into the mixing tank (110), the solution is stirred until a homogeneous solution is obtained. Step c) is to repeat Sub-steps c1) and c2) until the electrolyte mixture contained in the electrolyte tank is completely dissolved.

Abstract: The present invention refers to a container comprising a connection portion allowing for an easy, efficient and more hygienic connection of the container to a fluid dosing unit of a blood treatment device. According to the present invention the fluid dosing unit comprises a valve that fluidically closes the fluid dosing unit if no container is connected to the fluid dosing unit and that opens the fluid dosing unit upon connection of a container to the fluid dosing unit. Thus, undesired spillages potentially arising upon disconnection of the container from the fluid dosing unit can be avoided.

Abstract: The invention relates to a method for manufacturing a liquid acid concentrate for hemodialysis machines, with the following steps. In a preliminary step a water source (120), an acid source (130), an electrolyte tank (140) containing a mixture of electrolytes in exactly the quantity needed for the manufacture of the liquid acid concentrate, and a sodium chloride source (150) are connected to a mixing tank (110). During Step a), the quantity of water needed for the manufacture of the batch of liquid acid concentrate is introduced into the mixing tank (110). At Step b), the quantity of acid needed for manufacture the liquid acid concentrate is introduced into the mixing tank (110), the solution is stirred until a homogeneous solution is obtained. Step c) is to repeat Sub-steps c1) and c2) until the electrolyte mixture contained in the electrolyte tank is completely dissolved.

Abstract: The present invention relates to a closing element for a fluid line, preferably a fluid line of a concentrate container, comprising a closing portion configured to be arranged on an end portion of the fluid line to fluidically close the fluid line, wherein the closing portion comprises an intended breaking point, and a pressure receiving portion configured to receive pressure applied by a connector element to be fluidically connected to the fluid line by breaking the intended breaking point, wherein the pressure receiving portion comprises at least one protrusion projecting outwards from at least a part of the closing element that is configured to come into contact with the connector element.

Abstract: A water source, an acid source, an electrolyte tank containing a mixture of electrolytes in exactly the quantity needed for the manufacture of the liquid acid concentrate, and a sodium chloride source are connected to a mixing tank. A quantity of water needed for the manufacture of the batch of liquid acid concentrate is introduced into the mixing tank. A quantity of acid needed for manufacture of the liquid acid concentrate is introduced into the mixing tank, the solution is stirred until a homogeneous solution is obtained. Part of the solution contained in the mixing tank is transferred into the electrolyte tank, then the solution contained in the electrolyte tank is transferred into the mixing tank. A quantity of sodium chloride needed to manufacture the liquid acid concentrate is introduced into the mixing tank. The solution is stirred and recirculated until a homogeneous liquid acid concentrate is obtained.

Abstract: The invention relates to a connector (1) constituted by: base provided with a tubular wall (13) closed by a bottom wall (11) provided with at least one through-opening (111); a membrane provided with a flexible wall (23) having a central opening, a tubing (22) placed in the opening of the flexible wall; sealing means for preventing a liquid from leaving the connector through the tubing. The base and the membrane are fixed to each other in a liquid-tight manner. The flexible wall allows axial displacement of the tubing so that it can be moved between a closed position, in which a liquid cannot leave the connector through the conduit of the tubing, and an open position, in which a liquid from can leave the connector through the tubing. Retaining means (121, 222a) maintain the tubing (22) closed with a force that can be overcome manually to open it.

Abstract: The present invention refers to a system and method for opening a concentrate container without the need for a human to directly handle the concentrate container and connecting the concentrate container to a blood treatment device. Aspects of the invention are directed to a container for concentrate and a blood treatment device.

Abstract: The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.

Abstract: The present invention refers to a system and method for opening a concentrate container without the need for a human to directly handle the concentrate container and connecting the concentrate container to a blood treatment device. Aspects of the invention are directed to a container for concentrate and a blood treatment device.

Abstract: The present invention refers to a container comprising a connection portion allowing for an easy, efficient and more hygienic connection of the container to a fluid dosing unit of a blood treatment device. According to the present invention the fluid dosing unit comprises a valve that fluidically closes the fluid dosing unit if no container is connected to the fluid dosing unit and that opens the fluid dosing unit upon connection of a container to the fluid dosing unit. Thus, undesired spillages potentially arising upon disconnection of the container from the fluid dosing unit can be avoided.

Abstract: The invention relates to a bag (1) made of a flexible wall, which bag is fitted with an inlet fluid line for introducing dissolution water, and with an outlet fluid line (121, 122) for extracting a solution obtained. According to the invention, the inside of the bag has a lower edge (13) in the overall shape of a V, the point of the V being further away from the centre of the bag than the arms of the V, the outlet fluid line opening into the bag as close as possible to the point of the V.

Abstract: The invention relates to a connector (1) constituted by: base provided with a tubular wall (13) closed by a bottom wall (11) provided with at least one through-opening (111); a membrane provided with a flexible wall (23) having a central opening, a tubing (22) placed in the opening of the flexible wall; sealing means for preventing a liquid from leaving the connector through the tubing. The base and the membrane are fixed to each other in a liquid-tight manner. The flexible wall allows axial displacement of the tubing so that it can be moved between a closed position, in which a liquid cannot leave the connector through the conduit of the tubing, and an open position, in which a liquid from can leave the connector through the tubing. Retaining means (121, 222a) maintain the tubing (22) closed with a force that can be overcome manually to open it.

Abstract: A precursor composition for the preparation of a dialysis fluid, the precursor composition comprising at least a glucose component, an acid component, and an amino acid component, wherein the amino acid component comprises Valine, Isoleucine and Leucine.