Abstract: The invention relates to a method for manufacturing a liquid acid concentrate for hemodialysis machines, with the following steps. In a preliminary step a water source (120), an acid source (130), an electrolyte tank (140) containing a mixture of electrolytes in exactly the quantity needed for the manufacture of the liquid acid concentrate, and a sodium chloride source (150) are connected to a mixing tank (110). During Step a), the quantity of water needed for the manufacture of the batch of liquid acid concentrate is introduced into the mixing tank (110). At Step b), the quantity of acid needed for manufacture the liquid acid concentrate is introduced into the mixing tank (110), the solution is stirred until a homogeneous solution is obtained. Step c) is to repeat Sub-steps c1) and c2) until the electrolyte mixture contained in the electrolyte tank is completely dissolved.

Abstract: The present invention refers to a container comprising a connection portion allowing for an easy, efficient and more hygienic connection of the container to a fluid dosing unit of a blood treatment device. According to the present invention the fluid dosing unit comprises a valve that fluidically closes the fluid dosing unit if no container is connected to the fluid dosing unit and that opens the fluid dosing unit upon connection of a container to the fluid dosing unit. Thus, undesired spillages potentially arising upon disconnection of the container from the fluid dosing unit can be avoided.

Abstract: The invention relates to a method for manufacturing a liquid acid concentrate for hemodialysis machines, with the following steps. In a preliminary step a water source (120), an acid source (130), an electrolyte tank (140) containing a mixture of electrolytes in exactly the quantity needed for the manufacture of the liquid acid concentrate, and a sodium chloride source (150) are connected to a mixing tank (110). During Step a), the quantity of water needed for the manufacture of the batch of liquid acid concentrate is introduced into the mixing tank (110). At Step b), the quantity of acid needed for manufacture the liquid acid concentrate is introduced into the mixing tank (110), the solution is stirred until a homogeneous solution is obtained. Step c) is to repeat Sub-steps c1) and c2) until the electrolyte mixture contained in the electrolyte tank is completely dissolved.

Abstract: The present invention relates to a closing element for a fluid line, preferably a fluid line of a concentrate container, comprising a closing portion configured to be arranged on an end portion of the fluid line to fluidically close the fluid line, wherein the closing portion comprises an intended breaking point, and a pressure receiving portion configured to receive pressure applied by a connector element to be fluidically connected to the fluid line by breaking the intended breaking point, wherein the pressure receiving portion comprises at least one protrusion projecting outwards from at least a part of the closing element that is configured to come into contact with the connector element.

Abstract: A water source, an acid source, an electrolyte tank containing a mixture of electrolytes in exactly the quantity needed for the manufacture of the liquid acid concentrate, and a sodium chloride source are connected to a mixing tank. A quantity of water needed for the manufacture of the batch of liquid acid concentrate is introduced into the mixing tank. A quantity of acid needed for manufacture of the liquid acid concentrate is introduced into the mixing tank, the solution is stirred until a homogeneous solution is obtained. Part of the solution contained in the mixing tank is transferred into the electrolyte tank, then the solution contained in the electrolyte tank is transferred into the mixing tank. A quantity of sodium chloride needed to manufacture the liquid acid concentrate is introduced into the mixing tank. The solution is stirred and recirculated until a homogeneous liquid acid concentrate is obtained.

Abstract: The invention relates to a connector (1) constituted by: base provided with a tubular wall (13) closed by a bottom wall (11) provided with at least one through-opening (111); a membrane provided with a flexible wall (23) having a central opening, a tubing (22) placed in the opening of the flexible wall; sealing means for preventing a liquid from leaving the connector through the tubing. The base and the membrane are fixed to each other in a liquid-tight manner. The flexible wall allows axial displacement of the tubing so that it can be moved between a closed position, in which a liquid cannot leave the connector through the conduit of the tubing, and an open position, in which a liquid from can leave the connector through the tubing. Retaining means (121, 222a) maintain the tubing (22) closed with a force that can be overcome manually to open it.

Abstract: The present invention refers to a system and method for opening a concentrate container without the need for a human to directly handle the concentrate container and connecting the concentrate container to a blood treatment device. Aspects of the invention are directed to a container for concentrate and a blood treatment device.

Abstract: The present invention refers to a system and method for connecting a concentrate container with a blood treatment device with improved hygiene. Furthermore, the invention refers to a container and blood treatment device to be used in a method according to the present invention.

Abstract: The present invention refers to a system and method for opening a concentrate container without the need for a human to directly handle the concentrate container and connecting the concentrate container to a blood treatment device. Aspects of the invention are directed to a container for concentrate and a blood treatment device.

Abstract: The present invention refers to a container comprising a connection portion allowing for an easy, efficient and more hygienic connection of the container to a fluid dosing unit of a blood treatment device. According to the present invention the fluid dosing unit comprises a valve that fluidically closes the fluid dosing unit if no container is connected to the fluid dosing unit and that opens the fluid dosing unit upon connection of a container to the fluid dosing unit. Thus, undesired spillages potentially arising upon disconnection of the container from the fluid dosing unit can be avoided.

Abstract: The invention relates to a bag (1) made of a flexible wall, which bag is fitted with an inlet fluid line for introducing dissolution water, and with an outlet fluid line (121, 122) for extracting a solution obtained. According to the invention, the inside of the bag has a lower edge (13) in the overall shape of a V, the point of the V being further away from the centre of the bag than the arms of the V, the outlet fluid line opening into the bag as close as possible to the point of the V.

Abstract: The invention relates to a connector (1) constituted by: base provided with a tubular wall (13) closed by a bottom wall (11) provided with at least one through-opening (111); a membrane provided with a flexible wall (23) having a central opening, a tubing (22) placed in the opening of the flexible wall; sealing means for preventing a liquid from leaving the connector through the tubing. The base and the membrane are fixed to each other in a liquid-tight manner. The flexible wall allows axial displacement of the tubing so that it can be moved between a closed position, in which a liquid cannot leave the connector through the conduit of the tubing, and an open position, in which a liquid from can leave the connector through the tubing. Retaining means (121, 222a) maintain the tubing (22) closed with a force that can be overcome manually to open it.

Abstract: A precursor composition for the preparation of a dialysis fluid, the precursor composition comprising at least a glucose component, an acid component, and an amino acid component, wherein the amino acid component comprises Valine, Isoleucine and Leucine.

Abstract: The present invention relates to a novel dry acid concentrate (DAC) for a dialysis liquid and to a dialysis liquid, which is made from said concentrate, and which may be used for purifying blood. The invention further relates to a method of making the dry acid concentrate as well as the dialysis liquid. It also relates to a container (10) comprising said acid concentrate, and which is—in certain embodiments—specially adapted to a dialysis unit.

Abstract: A precursor composition for the preparation of a dialysis fluid, the precursor composition comprising at least a glucose component, an acid component, and an amino acid component, wherein the amino acid component comprises Valine, Isoleucine and Leucine.

Abstract: The invention relates to a haemostatic bracelet (1) comprising: —a clamp comprising two branches (11, 12) and a first strut (13), each branch (11, 12) being connected by one of its ends to the other branch by means of the first strut (13), —a compression element (24) placed, when the bracelet is ready for use, inside the space defined by the branches (11, 12) and the first strut (13) of the clamp or inside a projection of this space, the compression element (24) protruding in the direction of the opening between the ends of the branches (11, 12) of the clamp opposite to the first strut (13), —actuation elements (30, 40) fixed to the branches (11, 12) of the clamp so that the ends of the branches (11, 12) of the clamp opposite to the first strut (13) can be spread by moving the ends of the actuation elements towards each other.

Abstract: The invention relates to a method for manufacturing a liquid acid concentrate for hemodialysis machines, with the following steps. In a preliminary step a water source (120), an acid source (130), an electrolyte tank (140) containing a mixture of electrolytes in exactly the quantity needed for the manufacture of the liquid acid concentrate, and a sodium chloride source (150) are connected to a mixing tank (110). During Step a), the quantity of water needed for the manufacture of the batch of liquid acid concentrate is introduced into the mixing tank (110). At Step b), the quantity of acid needed for manufacture the liquid acid concentrate is introduced into the mixing tank (110), the solution is stirred until a homogeneous solution is obtained. Step c) is to repeat Sub-steps c1) and c2) until the electrolyte mixture contained in the electrolyte tank is completely dissolved.

Abstract: A combination includes a container having a connecting portion, and a fluid preparation device, in particular a dialysis machine. The fluid preparation device is configured for mounting and connecting the connecting portion of the container. The fluid preparation device includes at least one line in fluid communication with an interior of the container in the connected position of the container. The container is filled with a first medium, and includes a reservoir containing a second medium. The fluid preparation device includes a rod-shaped element for opening the reservoir so that the first medium and the second medium are mixed with each other.

Abstract: The present invention relates to a novel dry acid concentrate (DAC) for a dialysis liquid and to a dialysis liquid, which is made from said concentrate, and which may be used for purifying blood. The invention further relates to a method of making the dry acid concentrate as well as the dialysis liquid. It also relates to a container (10) comprising said acid concentrate, and which is—in certain embodiments—specially adapted to a dialysis unit.

Abstract: The present invention relates to a novel dry acid concentrate (DAC) for a dialysis liquid and to a dialysis liquid, which is made from said concentrate, and which may be used for purifying blood. The invention further relates to a method of making the dry acid concentrate as well as the dialysis liquid. It also relates to a container (10) comprising said acid concentrate, and which is—in certain embodiments—specially adapted to a dialysis unit.