Patents by Inventor Philippe Le Goff

Philippe Le Goff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the synthesis of substituted carbodiimides
    Patent number: 5648537
    Abstract: The invention relates to a new process for the synthesis of a disubstituted carbodiimide, including a first stage of phosgenation of an N,N'-disubstituted urea in an organic solvent medium.After this first stage ammonia is added to the reaction mixture without preliminary isolation of any intermediate compound.The process is simple, relatively inexpensive and the yield is high.Disubstituted carbodiimides are organic synthesis intermediates used especially in pharmaceutical chemistry as coupling agents in peptide synthesis.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: July 15, 1997
    Assignee: Societe Nationale des Poudres et Explosifs
    Inventors: Patricia Hussenet, Philippe Le Goff, Gerard Sennyey
  • Process for the preparation of acyl isocyanates
    Patent number: 5386057
    Abstract: The invention concerns a process for the preparation of acyl isocyanates which consists of reacting oxalyl chloride with a salt selected from the group consisting of hydrohalides and sulphates of carboxamides and/or carbamates, unsubstituted on nitrogen, then heating the reaction mixture at a temperature between 30.degree. and 150.degree. C. The process is suitable for preparation of acyl isocyanates with excellent yields in easy to control operational conditions.
    Type: Grant
    Filed: August 2, 1993
    Date of Patent: January 31, 1995
    Assignees: Societe Nationale des Poudres et Explosifs, Nippon Paint Co. Ltd.
    Inventors: Philippe Le Goff, Daniele Dewilde, Noriyuki Tsuboniwa, Satoshi Urano