Patents by Inventor Philippe Lebrun

Philippe Lebrun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8069679
    Abstract: The invention concerns an installation for cryogenic cooling comprising: a main reservoir (1) for a two-phase cryogenic fluid wherein is immersed a superconductor device (4) to be cooled; an auxiliary reservoir (9); and a hydrostatic duct between the bases of the main and auxiliary reservoirs; the auxiliary reservoir being arranged relative to the main reservoir and being dimensioned so as to be able to receive at least a large part of the cryogenic fluid present in liquid form (2) in the main reservoir; restricting means (11) being incorporated in an output manifold (7a) connected to the main reservoir; thus, when the superconductor gets rapidly heated, cryogenic liquid from the main reservoir is delivered, by the vaporized cryogenic fluid pressure, into the auxiliary reservoir wherefrom it flows again by gravity towards the main reservoir when the pressure of the vaporized fluid decreases.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: December 6, 2011
    Assignee: Organisation Europeenne pour la Recherche Nucleaire
    Inventors: Philippe Lebrun, Bruno Vullierme
  • Patent number: 7507761
    Abstract: The invention relates to novel benzopyran derivatives of formula I, to their method of production, to composition comprising the derivatives and use thereof.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: March 24, 2009
    Assignees: Universite de Liege, Universite Libre de Bruxelles
    Inventors: Sophie Sebille, Bernard Pirotte, Stéphane Boverie, Pascal De Tullio, Philippe Lebrun, Marie-Hélène Antoine
  • Publication number: 20080134691
    Abstract: The invention concerns an installation for cryogenic cooling comprising: a main reservoir (1) for a two-phase cryogenic fluid wherein is immersed a superconductor device (4) to be cooled; an auxiliary reservoir (9); and a hydrostatic duct between the bases of the main and auxiliary reservoirs; the auxiliary reservoir being arranged relative to the main reservoir and being dimensioned so as to be able to receive at least a large part of the cryogenic fluid present in liquid form (2) in the main reservoir; restricting means (11) being incorporated in an output manifold (7a) connected to the main reservoir; thus, when the superconductor gets rapidly heated, cryogenic liquid from the main reservoir is delivered, by the vaporized cryogenic fluid pressure, into the auxiliary reservoir wherefrom it flows again by gravity towards the main reservoir when the pressure of the vaporized fluid decreases.
    Type: Application
    Filed: January 24, 2006
    Publication date: June 12, 2008
    Inventors: Philippe Lebrun, Bruno Vullierme
  • Publication number: 20070112063
    Abstract: The invention relates to novel benzopyran derivatives of formula I, to their method of production, to composition comprising the derivatives and use thereof.
    Type: Application
    Filed: January 21, 2005
    Publication date: May 17, 2007
    Inventors: Sophie Sebille, Bernard Piroite, Stephane Boverie, Pascal De Tullio, Philippe Lebrun, Marie-Helene Antoine
  • Patent number: 7122380
    Abstract: A pharmaceutical composition suitable for administration to human beings in the prevention or treatment of immunologic disorders includes: an immune complex of an antigen and a purified antibody specific thereto, the antigen being selected from a group consisting of antigens that cause pathogenic immunologic reactions in autoimmune disease and graft rejections, and the antigen and antibody being present in a ratio whereby the antibody blocks essentially all binding sites of the antigen; and a pharmacologically acceptable carrier or diluent. The invention also provides a method of administering the composition for treatment of autoimmune disease and treatment or prevention of graft rejections.
    Type: Grant
    Filed: May 13, 1994
    Date of Patent: October 17, 2006
    Assignee: International Institute of Cellular and Molecular Pathology
    Inventors: Marc Jacquemin, Jean-Marie St. Remy, Philippe Lebrun, Serge Lebecque, Piere Masson
  • Patent number: 6242443
    Abstract: 1,2,4-Benzothiadiazine derivatives represented by formula wherein D, R1, R2, R3, R4, R5, R12, R13, R14, R15 are defined in the description, composition thereof and methods for preparing the compounds are described. The compounds are useful in the treatment of diseases of the central nervous system, the cardiovascular system, the pulmonary system, the gastrointestinal system and the endocrinological system.
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: June 5, 2001
    Assignee: Novo Nordisk AIS
    Inventors: Bernard Pirotte, Philippe Lebrun, Pascal De Tullio, Fabian Somers, Jacques Delarge, John Bondo Hansen, Flemming Elmelund Nielsen, Holger Claus Hansen, John Patrick Mogensen, Tina Møller-Tagmose
  • Patent number: 5792764
    Abstract: Pyrido-1,2,4-thiadiazine and pyrido-1,4-thiazine derivatives represented by the formula ##STR1## wherein A, B, D, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are defined in the description, compositions thereof and methods for preparing the compounds are described. The compounds are useful in the treatment of diseases of the central nervous system, the cardiovascular system, pulmonary system, the gastrointestinal system and the endocrinologic system.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: August 11, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Bernard Pirotte, Philippe Lebrun, Pascal De Tullio, Fabian Somers, Jacques Delarge, Holger Claus Hansen, Flemming Elmelund Nielsen, John Bondo Hansen
  • Patent number: 5543145
    Abstract: A pharmaceutical composition suitable for administration to human beings for suppressing the production of factor VIII inhibitor includes:an immune complex of factor VIII antigen component and factor VIII inhibitor component, the components being present in a ratio such that the inhibitor blocks essentially all relevant binding sites of the antigen; anda pharmacologically acceptable carrier or diluent. The invention also provides a method of administering the compositions to suppress the production of inhibitor to factor VIII.
    Type: Grant
    Filed: July 21, 1994
    Date of Patent: August 6, 1996
    Assignees: Baxter International, Inc., International Institute of Cellular and Molecular Pathology
    Inventors: Jean-Marie Saint-Remy, Philippe Lebrun, Serge Lebeque, Pierre L. Masson, Henry S. Kingdon
  • Patent number: 5026545
    Abstract: A pharmaceutical composition comprises an immune complex of an allergen and a purified antibody specific thereto, the allergen being selected from a specific subclass of antigen which causes immediate hypersensitivity that is mediated by IgE antibody, and a pharmacologically acceptable carrier or diluent. The method of using the compositions in the treatment of immediate hypersensitivity to the allergen is also described.
    Type: Grant
    Filed: September 20, 1989
    Date of Patent: June 25, 1991
    Assignees: Baxter International, Inc., International Institute of Cellular and Molecular Pathology
    Inventors: Jean-Marie Saint-Remy, Philippe Lebrun, Serge Lebeque, Pierre L. Masson
  • Patent number: 4740371
    Abstract: In the treatment of allergy, desensitization is effected by administering the allergen in admixture with an antibody thereto, the antibody being present in a molar excess. The antibody is preferably one raised in the patient.
    Type: Grant
    Filed: September 17, 1984
    Date of Patent: April 26, 1988
    Assignee: International Institute of Cellular and Molecular Pathology
    Inventors: Jean-Marie St. Remy, Philippe Lebrun, Serge Lebecque, Pierre Masson
  • Patent number: 4442091
    Abstract: The invention provides a method for combatting and/or preventing allergic diseases which are caused by house-dust mites by treating said mites or places or areas which are afflicted or may be afflicted by said mites with an effective amount of natamycin.
    Type: Grant
    Filed: April 29, 1982
    Date of Patent: April 10, 1984
    Assignee: Gist-Brocades N.V.
    Inventors: Philippe Lebrun, Daniele de Saint Georges-Gridelet