Abstract: A non-uniform memory access (NUMA) computer system includes at least two nodes coupled by a node interconnect, where at least one of the nodes includes a processor for servicing interrupts. The nodes are partitioned into external interrupt domains so that an external interrupt is always presented to a processor within the external interrupt domain in which the interrupt occurs. Although each external interrupt domain typically includes only a single node, interrupt channeling or interrupt funneling may be implemented to route external interrupts across node boundaries for presentation to a processor. Once presented to a processor, interrupt handling software may then execute on any processor to service the external interrupt. Servicing external interrupts is expedited by reducing the size of the interrupt handler polling chain as compared to prior art methods.