Abstract: The present invention relates to a method of treatment of a mucopolysaccharidosis with 4-methyl-2-oxo-2H-1-benzopyran-7-yl-5-thio-?-D-xylopyranoside.

Abstract: The method of controlling a polyphase rotating electric machine, the machine operating as a generator and being linked to an electrical network (1), is of the type of those consisting in short-circuiting at least one phase winding in the event of load shedding. A short-circuit command (SAND) is generated for the phase winding when a first measurement voltage V of a voltage B+ of the network exceeds a first predetermined threshold value V1 and when a phase current (I?) in the phase winding vanishes and changes direction. The first measurement voltage V may be obtained by filtering the voltage B+ of the network with a predetermined time constant TF.

Abstract: A method of controlling a supercapacitor energy storage unit (12), included in a motor vehicle micro-hybrid system, is disclosed. The storage unit is suitable for performing the functions of an alternator, starter and automatic stop-restart of the vehicle heat engine, regenerative braking and torque assistance. The energy storage unit (12) is a plurality of supercapacitor elementary cells connected in series (C1 to C10) and capable of delivering information (Vmax, Temp and DeltaV) on its internal status. The method includes various stages of: comparing a maximum elementary voltage (Vmax) with a first voltage threshold (Vmax1); comparing a temperature (Temp) with at least one temperature threshold (ST1=55° C., ST2=65° C. and ST3=70° C.); and, deciding on limitations of the availability of functions of the unit when the (Vmax) information reaches threshold (Vmax1) for a predetermined duration (T) and/or when the (Temp) information reaches the temperature threshold (ST1=55° C., ST2=65° C. and ST3=70° C.).

Abstract: A method of controlling a supercapacitor energy storage unit (12), included in a motor vehicle micro-hybrid system, is disclosed. The storage unit is suitable for performing the functions of an alternator, starter and automatic stop-restart of the vehicle heat engine, regenerative braking and torque assistance. The energy storage unit (12) is a plurality of supercapacitor elementary cells connected in series (C1 to C10) and capable of delivering information (Vmax, Temp and DeltaV) on its internal status. The method includes various stages of: comparing a temperature (Temp) with at least one temperature threshold (ST1=55° C., ST2=65° C. and ST3=70° C.); and, deciding on limitations of the availability of functions of the unit when the (Temp) information reaches the temperature threshold (ST1=55° C., ST2=65° C. and ST3=70° C.).

Abstract: The method of detecting the failure of the excitation circuit of a polyphase alternator controlled by a regulator comprises the following steps: a) electrical information (Iexc) is continuously taken from the excitation circuit (1); b) the electrical information taken in step a) is continuously compared with a predetermined threshold value (Iref); c) a logic state (LT) is continuously determined according to the result of the comparison made in step b); and d) if the logic state (LT) determined in step c) persists for a time at least equal to a predetermined delay time (6), an electrical continuity fault of said excitation circuit is signalled. This method is particularly suitable for machines having a rotor equipped with permanent magnets or having a high remanence of the magnetic circuit of the rotor.

Abstract: The member for a synchronous rectifier bridge (14) typically includes at least first and second connection terminals (B+, P), at least one field-effect transistor (15) having source and drain electrodes (16, 17) respectively connected to the first and second terminals (B+, P), and at least one comparator for comparing at least a first voltage source having a predetermined reference voltage and at least a first voltage difference between the voltages applied to the first and second terminals (B+, P) and having an output connected to a gate electrode (21) of the transistor (15). The member (14) further includes at least one load pump (25) providing, from the applied voltages, at least one supply voltage (VH, VL), of an amplifier from said applied voltages.

Abstract: The method of detecting the failure of the excitation circuit of a polyphase alternator controlled by a regulator comprises the following steps: a) electrical information (Iexc) is continuously taken from the excitation circuit (1); b) the electrical information taken in step a) is continuously compared with a predetermined threshold value (Iref); c) a logic state (LT) is continuously determined according to the result of the comparison made in step b); and d) if the logic state (LT) determined in step c) persists for a time at least equal to a predetermined delay time (6), an electrical continuity fault of said excitation circuit is signalled. This method is particularly suitable for machines having a rotor equipped with permanent magnets or having a high remanence of the magnetic circuit of the rotor.

Abstract: A method of controlling a supercapacitor energy storage unit (12), included in a motor vehicle micro-hybrid system, is disclosed. The storage unit is suitable for performing the functions of an alternator, starter and automatic stop-restart of the vehicle heat engine, regenerative braking and torque assistance. The energy storage unit (12) is a plurality of supercapacitor elementary cells connected in series (C1 to C10) and capable of delivering information (Vmax, Temp and DeltaV) on its internal status. The method includes various stages of: comparing a temperature (Temp) with at least one temperature threshold (ST1=55° C., ST2=65° C. and ST3=70° C.); and, deciding on limitations of the availability of functions of the unit when the (Temp) information reaches the temperature threshold (ST1=55° C., ST2=65° C. and ST3=70° C.).

Abstract: A method of controlling a supercapacitor energy storage unit (12), included in a motor vehicle micro-hybrid system, is disclosed. The storage unit is suitable for performing the functions of an alternator, starter and automatic stop-restart of the vehicle heat engine, regenerative braking and torque assistance. The energy storage unit (12) is a plurality of supercapacitor elementary cells connected in series (C1 to C10) and capable of delivering information (Vmax, Temp and DeltaV) on its internal status. The method includes various stages of: comparing a maximum elementary voltage (Vmax) with a first voltage threshold (Vmax1); comparing a temperature (Temp) with at least one temperature threshold (ST1=55° C., ST2=65° C. and ST3=70° C.); and, deciding on limitations of the availability of functions of the unit when the (Vmax) information reaches threshold (Vmax1) for a predetermined duration (T) and/or when the (Temp) information reaches the temperature threshold (ST1=55° C., ST2=65° C. and ST3=70° C.).

Abstract: A system and method for generating a magnetic field in a rotating machine. In one embodiment, a primary winding assembly is configured to generate a rotatable magnetic field. The assembly is connected to receive multiple signals of different phases to effect field rotation. A set of secondary windings is positioned for generation of current based on magnetic coupling during the field rotation. The secondary windings include conductor capable of supporting superconducting current flow. A rotatable machine includes a stator and a rotor winding coupled for rotation with respect to the stator. The secondary windings are formed in a circuit for providing superconducting current through the rotor winding.

Abstract: An alternating current machine which generates a magnetic field or induces a voltage. In one embodiment the machine includes a stator and a rotor positioned about an axis. The stator includes three sets of coils, each set including at least a first pair of coil rows wired in series, with first and second members of the first pair configured to generate axial fields in opposite directions. Coil rows in the first pair of each set of coils are each arranged a different distance from the axis. A first member of the pair of the second set of coil rows is positioned between the first and second members of the pair of the first set of coil rows. The distance between the axis and the first member of the second pair of coil rows is intermediate the distances between the members of the first pair of coil rows and the axis.

Abstract: A micro-hybrid method and device for a motor vehicle. The device comprises, in an electrical cascade connection, a rotary electric machine, an AC-to-DC converter and a DC electrical supply bus, the DC electrical supply bus being connected to the AC-to-DC converter and being suitable for being connected to the terminals of an energy storage battery supplying an electrical distribution network of the vehicle. The device also comprises large capacity energy storage means which are mounted in parallel in relation to the cascade connection.

Abstract: The Invention relates to a method for preparing a combretastatin (A): formula (I) in the form of a base or of an addition salt with an acid, which comprises coupling, in the presence of a base and of T3P, the salt of the (Z)-amino compound of formula (II) with a doubly protected L-serine derivative of formula (III) in which PG denotes a group protecting the amine function, so as to obtain the compound of formula (Z)-(Ib): formula (IV), then deprotecting and opening the ring of (Z)-(Ib) in the presence of an acid, so as to obtain the combretastatin (A) in the form of a salt; and, optionally, adding a base, so as to obtain the combretastatin (A) in the form of a base, the salt of the (Z)-amino compound having been obtained by enrichment of the salt of the amino compound of formula (V) in (Z) isomer.

Abstract: Benzenesulfonamide derivative compounds corresponding to the general formula (I): and their pharmaceutically acceptable addition salts; a process for preparation of such compounds; pharmaceutical compositions containing such compounds, and the use of such compounds as a pharmacologically active substance, in particular in the treatment of neurodegenerative diseases, cardiovascular diseases, inflammatory diseases; hypercholesterolemia, and diabetes.

Abstract: A high temperature superconducting synchronous motor having an inductor topology that increases the air gap flux density in direct relation to motor power density by trapping flux and concentrating it in the air gap to obtain more power in the same volume or smaller volume for the same power, and whose geometry enables the induction motor to be lighter than superconducting motors without the inductor topology, the motor being positioned in a housing, and the motor comprising: a) stator means having an armature winding to provide a stator field; c) rotor means positioned within the stator field and on which is disposed at least two polygon shaped ring or coil means along the same axis to provide separated and spaced apart relationship field solenoids; c) at least four high temperature superconducting plate means disposed in alternating relationship between the ring or coil means to hold the ring or coil means together to trap magnetic field and shape flux lines; and d) cooling means to cool the superconduct

Abstract: The member for a synchronous rectifier bridge (14) typically includes at least first and second connection terminals (B+, P), at least one field-effect transistor (15) having source and drain electrodes (16, 17) respectively connected to the first and second terminals (B+, P), and at least one comparator for comparing at least a first voltage source having a predetermined reference voltage and at least a first voltage difference between the voltages applied to the first and second terminals (B+, P) and having an output connected to a gate electrode (21) of the transistor (15). The member (14) further includes at least one load pump (25) providing, from the applied voltages, at least one supply voltage (VH, VL), of an amplifier from said applied voltages.

Abstract: An alternating current machine which generates a magnetic field or induces a voltage. In one the machine includes a stator and a rotor positioned about an axis. The stator includes three sets of coils, each set including at least a first pair of coil rows wired in series, with first and second members of the first pair configured to generate axial fields in opposite directions. Coil rows in the first pair of each set of coils are each arranged a different distance from the axis. A first member of the pair of the second set of coil rows is positioned between the first and second members of the pair of the first set of coil rows. The distance between the axis and the first member of the second pair of coil rows is intermediate the distances between the members of the first pair of coil rows and the axis.

Abstract: A micro-hybrid method and device for a motor vehicle. The device comprises, in an electrical cascade connection, a rotary electric machine, an AC-to-DC converter and a DC electrical supply bus, the DC electrical supply bus being connected to the AC-to-DC converter and being suitable for being connected to the terminals of an energy storage battery supplying an electrical distribution network of the vehicle. The device also comprises large capacity energy storage means which are mounted in parallel in relation to the cascade connection.

Abstract: A system and method for generating a magnetic field in a rotating machine. In one embodiment, a primary winding assembly is configured to generate a rotatable magnetic field. The assembly is connected to receive multiple signals of different phases to effect field rotation. A set of secondary windings is positioned for generation of current based on magnetic coupling during the field rotation. The secondary windings include conductor capable of supporting superconducting current flow. A rotatable machine includes a stator and a rotor winding coupled for rotation with respect to the stator. The secondary windings are formed in a circuit for providing superconducting current through the rotor winding.

Abstract: The alternator comprises a wound rotor and a stator with a number of phases connected to a rectifier bridge equipped with switches (7) in the form of MOS type transistors, such as MOSFET type transistors, characterised in that the transistors (7) are voltage-rated to work by avalanche effect or linearly in the case of a load dump.