Patents by Inventor Philippe Msika

Philippe Msika has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7589121
    Abstract: The invention relates to the use of one or several synthetic or natural furan alkyls for preparing a drug preventing and/or treating obesity or overweight. The use of one or several synthetic or natural furan alkyls for cosmetically treating local excessive weight is also disclosed. Said furan alkyls preferably correspond to formula (I), wherein identical or different R1, R2, R3et R4 are independently of each other a hydrogen atom, a C1-C35alkyl radical, C1-C35 alcenyl radical or a C1-C35 alcynyl radical, preferably C10-C22, wherein said alkyl, alcenyl and alcynyl radicals are substitutable and R1, R2, R3 are preferably a hydrogen atom.
    Type: Grant
    Filed: May 27, 2005
    Date of Patent: September 15, 2009
    Assignee: Laboratoires Expanscience
    Inventors: Antoine Piccirilli, Philippe Msika, Nathalie Piccardi
  • Publication number: 20090196837
    Abstract: The present invention concerns the use of a rice protein hydrolysate in order to pigment the skin and skin appendages. Thus, it is possible to intensify the normal pigmentation of the skin without sunlight. Preferred areas of applications are repigmentation of white patches of the skin, repigmentation of white patches of the skin as a consequence of pityriasis or due to the use of dermocorticoids; acceleration and intensification of the tanning process, stimulation of the constitutive photoprotection and improvement of the phototype, prevention of skin photocarcinogenesis. Advantageously, the rice protein hydrolysate comprises peptides of which at least 50% have a molecular mass in the range of between 300 and 3,500 Da.
    Type: Application
    Filed: July 18, 2007
    Publication date: August 6, 2009
    Inventors: Philippe Msika, Dalale Naaïmi
  • Publication number: 20090175965
    Abstract: The invention relates to the use of at least one unsaponifiable component of vegetable oil, in particular of avocado, soya bean and/or lupin oils, for the preparation of a medicament intended to stimulate the expression of TGF-? or the expression of the plasminogen activator inhibitor PAI-1. The invention also relates to a method of cosmetic treatment comprising the application of at least one unsaponifiable component of vegetable oil as well as the use of the latter as additive in a food for human beings and/or for animals.
    Type: Application
    Filed: October 2, 2008
    Publication date: July 9, 2009
    Inventors: Karim Boumediene, Jean-Pierre Pujol, Georges Bernard Guillou, Philippe Msika, Chafik Ghayor
  • Publication number: 20090163590
    Abstract: The present invention concerns a process for producing refined avocado oil rich in triglycerides. The invention also pertains to refined avocado oil rich in triglycerides obtainable by said process. Advantageously, the refined avocado oil of the invention contains a sterols-enriched unsaponifiable fraction. Advantageously, the refined avocado oil of the invention is substantially free of acetogenins and furanic lipids. The invention also concerns compositions containing said oil. The invention also pertains to such compositions for use as a medication, as a dermatological agent, as a cosmetic agent, or as a nutriceutical, for human or animal use.
    Type: Application
    Filed: February 27, 2009
    Publication date: June 25, 2009
    Inventors: Philippe MSIKA, Jacques Legrand
  • Publication number: 20090137453
    Abstract: The invention concerns a composition containing at least an oxazolin, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an alkanolamide, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such composition on the skin and/or mucosa.
    Type: Application
    Filed: January 13, 2009
    Publication date: May 28, 2009
    Inventors: Philippe MSIKA, Nathalie PICCARDI, Antoine PICCIRILLI
  • Patent number: 7511010
    Abstract: The invention concerns a pharmaceutical or cosmetic composition, characterised in that it comprises at least a compound for inhibiting Langerhans' cell migration, said active compound being selected in the group consisting of protein kinase C (PKC) inhibiting compounds, matrix metalloprotease (MMP) inhibiting compounds, and combinations thereof, and at least a pharmaceutically or cosmetically acceptable carrier. Said composition enables to inhibit considerably Langerhans' cell migration induced by the presence or an allergenic agent.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: March 31, 2009
    Assignee: Laboratoires Expanscience
    Inventors: Philippe Msika, Nathalie Piccardi, Antoine Piccirilli
  • Patent number: 7473434
    Abstract: The invention relates to a method for extracting substances from maca, to the obtained extract, to a cosmetic and pharmaceutical composition containing said extract, and to the use thereof as an anti-aging cosmetic agent. The method is characterized by a step involving the use of an enzymatic hydrolysis of proteins.
    Type: Grant
    Filed: June 17, 2004
    Date of Patent: January 6, 2009
    Assignee: Laboratoires Expanscience
    Inventors: Nathalie Piccardi, Antoine Piccirilli, Philippe Msika, François Paul
  • Publication number: 20080292613
    Abstract: The present invention relates to the use of a combination of group B vitamins, trace element(s), at least one oil comprising essential ?-3 and/or ?-6 fatty acids and an excipient suitable for oral administration, for use in the simultaneous treatment of excess weight and slackening of the skin localized in the same area. The invention also relates to a corresponding food supplement.
    Type: Application
    Filed: December 15, 2006
    Publication date: November 27, 2008
    Inventors: Philippe Msika, Nathalie Piccardi, Pascale Cochet, Michel Moreau
  • Patent number: 7449487
    Abstract: The invention relates to the use of at least one unsaponifiable component of vegetable oil, in particular of avocado, soya bean and/or lupin oils, for the preparation of a medicament intended to stimulate the expression of TGF-? or the expression of the plasminogen activator inhibitor PAI-1. The invention also relates to a method of cosmetic treatment comprising the application of at least one unsaponifiable component of vegetable oil as well as the use of the latter as additive in a food for human beings and/or for animals.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: November 11, 2008
    Assignee: Laboratoires Expanscience
    Inventors: Karim Boumediene, Jean-Pierre Pujol, Georges Bernard Guillou, Philippe Msika, Chafik Ghayor
  • Publication number: 20080219937
    Abstract: The invention concerns the cosmetic use of at least one 2-alkyl furan, as depigmenting active principle, in a depigmenting composition, as well as the associated cosmetic treatment method. The invention also concerns the use of at least one 2-alkyl furan for preparing an active drug as depigmenting agent. The invention further concerns a depigmenting cosmetic composition comprising as depigmenting active principle at least one 2-alkyl furan.
    Type: Application
    Filed: August 30, 2006
    Publication date: September 11, 2008
    Applicant: LABORATOIRES EXPANSCIENCE
    Inventors: Philippe Msika, Nathalie Piccardi
  • Publication number: 20080221017
    Abstract: The invention concerns a pharmaceutical or cosmetic composition, characterized in that it comprises at least a compound for inhibiting Langerhans' cell migration, said active compound being selected in the group consisting of protein kinase C (PKC) inhibiting compounds, matrix metalloprotease (MMP) inhibiting compounds, and combinations thereof, and at least a pharmaceutically or cosmetically acceptable carrier. Said composition enables to inhibit considerably Langerhans' cell migration induced by the presence of an allergenic agent.
    Type: Application
    Filed: March 3, 2008
    Publication date: September 11, 2008
    Inventors: Philippe Msika, Nathalie Piccardi, Antoine Piccirilli
  • Publication number: 20080194476
    Abstract: The invention relates to a medicament which comprises a peptide extract of avocado and which can also comprise a composition containing D-mannoheptulose and/or perseitol, such as a water-soluble extract of avocado sugars, and/or a peptide extract of lupine. The inventive medicament is intended for the treatment and/or prevention of illnesses that are linked to an alteration in innate and/or acquired immunity, through an increase in the production of anti-microbial peptides, preferably hBD-2, without inducing inflammatory reactions, irritations or intolerances.
    Type: Application
    Filed: April 29, 2005
    Publication date: August 14, 2008
    Applicant: LABORATOIRES EXPANSCIENCE
    Inventors: Antoine Piccirilli, Nathalie Piccardi, Philippe Msika, Francois Paul, Stephanie Bredif
  • Publication number: 20080113921
    Abstract: The invention relates to the use of a compound comprising D-mannoheptulose and/or perseitol for producing a drug for treating and/or preventing diseases related to the modification of an innate and/or acquired immunity by increasing the production of antimicrobial peptides, preferably hBD-2 without inducing inflammatory reactions, irritation or intolerance. Said compound can also comprise a peptidic avocado extract and/or a peptidic lupin extract.
    Type: Application
    Filed: April 29, 2005
    Publication date: May 15, 2008
    Applicant: LABORATOIRES EXPANSCIENCE
    Inventors: Antoine Piccirilli, Nathalie Piccardi, Philippe Msika, Francois Paul, Stéphanie Bredif
  • Publication number: 20080081837
    Abstract: The invention relates to using one or several synthetic or natural furan alkyls for preparing a drug for preventing and/or treating diabetes and insulin resistance, thereby preventing the risks of cardiovascular, nervous, cutaneous, renal, ocular and infectious diseases. The use of one or several synthetic or natural furan alkyls for cosmetically treating diabetes related skin disorders is also disclosed.
    Type: Application
    Filed: May 27, 2005
    Publication date: April 3, 2008
    Inventors: Antoine Piccirilli, Philippe Msika, Nathalie Piccardi
  • Publication number: 20070281994
    Abstract: The invention relates to the use of one or several synthetic or natural furan alkyls for cosmetically treating cellulite. Said furan alkyls preferably correspond to formula (I), wherein identical or different R1, R2, R3 et R4 are independently of each other a hydrogen atom, a C1-C35alkyl radical, C1-C35 alcenyl radical or a C1-C35 alcynyl radical, preferably C10-C22, wherein said alkyl, alcenyl and alcynyl radicals are substitutable and R1, R2, R3 are preferably a hydrogen atom.
    Type: Application
    Filed: May 27, 2005
    Publication date: December 6, 2007
    Inventors: Antoine Piccirilli, Philippe Msika, Nathalie Piccardi
  • Publication number: 20070238777
    Abstract: The invention relates to the use of one or several synthetic or natural furan alkyls for preparing a drug preventing and/or treating obesity or overweight. The use of one or several synthetic or natural furan alkyls for cosmetically treating local excessive weight is also disclosed. Said furan alkyls preferably correspond to formula (I), wherein identical or different R1, R2, R3et R4 are independently of each other a hydrogen atom, a C1-C35alkyl radical, C1-C35 alkenyl radical or a C1-C35 alcynyl radical, preferably C10-C22, wherein said alkyl, alkenyl and alcynyl radicals are substitutable and R1, R2, R3 are preferably a hydrogen atom.
    Type: Application
    Filed: May 27, 2005
    Publication date: October 11, 2007
    Inventors: Antoine Piccirilli, Philippe Msika, Nathalie Piccardi
  • Patent number: 7238377
    Abstract: The invention concerns the use of at least an oil derived from the seeds of the gourd family selected from the group consisting of Lagenaria, Luffa and Momordica, for preparing a composition designed to inhibit 5?-reductase activity, and the use of said oil for preparing a composition for treating prostatic hypertrophy, prostatic adenoma, acne, hyperseborrhea, alopecia, and hirsutism. The invention also concerns cosmetic treatment methods, in particular for greasy skin. The invention further concerns the use of at least an oil derived from seeds of the gourd family in a nutritional food composition for humans and/or animals as additive for inhibiting 5? reductase activity.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: July 3, 2007
    Assignee: Laboratoires Expanscience
    Inventors: Antoine Piccirilli, Jacqueline Smadja, Philippe Msika, Isabelle Grondin, Nathalie Piccardi
  • Publication number: 20070116812
    Abstract: The present invention concerns a process for producing refined avocado oil rich in triglycerides. The invention also pertains to refined avocado oil rich in triglycerides obtainable by said process. Advantageously, the refined avocado oil of the invention contains a sterols-enriched unsaponifiable fraction. Advantageously, the refined avocado oil of the invention is substantially free of acetogenins and furanic lipids. The invention also concerns compositions containing said oil. The invention also pertains to such compositions for use as a medication, as a dermatological agent, as a cosmetic agent, or as a nutriceutical, for human or animal use.
    Type: Application
    Filed: November 16, 2006
    Publication date: May 24, 2007
    Applicants: Philippe MSIKA, Jacques LEGRAND
    Inventors: Philippe Msika, Jacques Legrand
  • Publication number: 20070098823
    Abstract: The invention relates to a method for extracting substances from maca, to the obtained extract, to a cosmetic and pharmaceutical composition containing said extract, and to the use thereof as an anti-aging cosmetic agent. The method is characterized by a step involving the use of an enzymatic hydrolysis of proteins.
    Type: Application
    Filed: June 17, 2004
    Publication date: May 3, 2007
    Applicant: LABORATOIRES EXPANSCIENCE
    Inventors: Nathalie Piccardi, Antoine Piccirilli, Philippe Msika, Francois Paul
  • Publication number: 20060216249
    Abstract: The present invention relates to the use of a lupeol-rich extract for the production of a cosmetic or pharmaceutical composition for treating and/or preventing a connective tissue degeneration. Said invention also relates to the use of a lupeol-rich extract for the production of a pharmaceutical composition for preventing and/or treating non-inflammatory articular pathologies, periodontal diseases and stretch marks. The invention also relates to the use of a lupeol-rich extract for the production of a cosmetic composition as a cicatrizing agent, a restructuring agent and an anti-sagging agent for skin and/or mucosae.
    Type: Application
    Filed: July 19, 2004
    Publication date: September 28, 2006
    Inventors: Philippe Msika, Antoine Piccirilli, Nathalie Piccardi