Patents by Inventor Philippe Panchaud
Philippe Panchaud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190315731Abstract: The invention relates to antibacterial compounds of formula I wherein the group M and R1 are as defined in the claims, and salts thereof.Type: ApplicationFiled: May 16, 2017Publication date: October 17, 2019Inventors: Stefan DIETHELM, Azely MIRRE, Philippe PANCHAUD, Christine SCHMITT, Jean-Luc SPECKLIN, Jean-Philippe SURIVET
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Patent number: 10441576Abstract: The invention relates to antibacterial compounds of formula I wherein M is one of the groups MA, MB and MC represented below and either R1 represents H and R2 represents a cleavable group as defined in the claims or R2 represents H and R1 represents a cleavable group as defined in the claims; and salts thereof.Type: GrantFiled: August 10, 2016Date of Patent: October 15, 2019Assignee: IDORSIA PHARMACEUTICALS LTD.Inventors: Stefan Diethelm, Philippe Panchaud, Georg Rueedi, Jean-Luc Specklin, Jean-Philippe Surivet
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Patent number: 10314823Abstract: The invention relates to antibacterial compounds of formula I wherein M is one of the groups MA, MB and MC represented below wherein R1, MA, MB and MC are as defined in the specification; and to salts thereof.Type: GrantFiled: September 2, 2016Date of Patent: June 11, 2019Assignee: IDORSIA PHARMACEUTICALS LTDInventors: Anne-Catherine Blumstein, Gaelle Mathieu, Loïc Jacob, Florence Masse, Azely Mirre, Philippe Panchaud, Christine Schmitt, Jean-Luc Specklin, Jean-Philippe Surivet
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Publication number: 20190031676Abstract: The invention relates to antibacterial compounds of formula I wherein X represents sulphur or CH?CH; R1 represents H, PO3H2, SO3H, phosphonooxymethyl or the group —CO—R2 wherein R2 is as defined in the claims M is one of the groups MA and MB represented below wherein A represents a bond or C?C and R1A, R2A, R3A and R1B are as defined in the claims; and to salts thereof.Type: ApplicationFiled: August 26, 2016Publication date: January 31, 2019Applicant: IDORSIA PHARMACEUTICALS LTDInventors: Philippe PANCHAUD, Christine SCHMITT, Jean-Philippe SURIVET
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Patent number: 10106544Abstract: The invention relates to antibacterial compounds of formula I wherein R1 is one of the groups represented below wherein A is a bond, CH?CH or C?C; U is N or CH; V is N or CH; W represents N or CH; and R1A, R2A, R3A, R1B and R1C are as defined in the claims; and salts thereof.Type: GrantFiled: March 3, 2015Date of Patent: October 23, 2018Assignee: IDORSIA PHARMACEUTICALS LTDInventors: Gaelle Chapoux, Jean-Christophe Gauvin, Azely Mirre, Philippe Panchaud, Christine Schmitt, Jean-Luc Specklin, Jean-Philippe Surivet
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Patent number: 10087171Abstract: The present invention relates to crystalline forms of cadazolid.Type: GrantFiled: December 18, 2017Date of Patent: October 2, 2018Inventors: Christian Hubschwerlen, Philippe Panchaud, Timo Rager, Jean-Luc Specklin
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Publication number: 20180250273Abstract: The invention relates to antibacterial compounds of formula I wherein M is one of the groups MA, MB and MC represented below wherein R1, MA, MB and MC are as defined in the specification; and to salts thereof.Type: ApplicationFiled: September 2, 2016Publication date: September 6, 2018Applicant: IDORSIA PHARMACEUTICALS LTD.Inventors: Anne-Catherine BLUMSTEIN, Gaelle MATHIEU, Loïc JACOB, Florence MASSE, Azely MIRRE, Philippe PANCHAUD, Christine SCHMITT, Jean-Luc SPECKLIN, Jean-Philippe SURIVET
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Publication number: 20180251434Abstract: The invention relates to antibacterial compounds of formula I wherein R1, M, R2, R3, and V are as described in the description, to their preparation, to salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula I, and especially to their use as antibacterial agents.Type: ApplicationFiled: August 30, 2016Publication date: September 6, 2018Inventors: Stefan DIETHELM, Jean-Christophe GAUVIN, Gaelle MATHIEU, Philippe PANCHAUD, Jean-Philippe SURIVET
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Publication number: 20180235938Abstract: The invention relates to antibacterial compounds of formula I wherein M is one of the groups MA, MB and MC represented below and either R1 represents H and R2 represents a cleavable group as defined in the claims or R2 represents H and R1 represents a cleavable group as defined in the claims; and salts thereof.Type: ApplicationFiled: August 10, 2016Publication date: August 23, 2018Inventors: Stefan DIETHELM, Philippe PANCHAUD, Georg RUEEDI, Jean-Luc SPECKLIN, Jean-Philippe SURIVET
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Publication number: 20180179196Abstract: The present invention relates to crystalline forms of cadazolid.Type: ApplicationFiled: December 18, 2017Publication date: June 28, 2018Inventors: Christian HUBSCHWERLEN, Philippe PANCHAUD, Timo RAGER, Jean-Luc SPECKLIN
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Publication number: 20170107223Abstract: The invention relates to antibacterial compounds of formula I wherein R1 is one of the groups represented below wherein A is a bond, CH?CH or C?C; U is N or CH; V is N or CH; W represents N or CH; and R1A, R2A, R3A, R1B and R1C are as defined in the claims; and salts thereof.Type: ApplicationFiled: March 3, 2015Publication date: April 20, 2017Inventors: Gaelle CHAPOUX, Jean-Christophe GAUVIN, Azely MIRRE, Philippe PANCHAUD, Christine SCHMITT, Jean-Luc SPECKLIN, Jean-Philippe SURIVET
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Patent number: 8889676Abstract: The invention relates to 3-ureidoisoquinolin-8-yl derivatives of formula I wherein R1 is alkyl, haloalkyl or cyclopropyl; R2 is H, halogen, pyridazin-4-yl, pyrimidin-5-yl or an optionally substituted pyridin-3-yl, pyridin-4-yl or phenyl group; R3 is alkyl, alkynyl, aminoalkyl, carbamoylalkyl, methylcarbamoylalkyl, alkoxy, haloalkoxy, alkynyloxy, (4-hydroxybut-2-yn-1-yl)oxy, (4-aminobut-2-yn-1-yl)oxy, dimethylaminoalkoxy, carbamoylalkoxy, alkylamino, cycloalkyl, cycloalkylalkyl, cycloalkylalkoxy, hydroxyalkyl, hydroxyalkoxy, alkoxyalkyl, alkoxyalkoxy, carboxyalkyl, carboxyalkoxy, alkoxycarbonylalkoxy, aryl, heteroaryl, benzyl, benzyloxy, 2-cyanoethoxy, 2,3-dihydroxypropoxy, 3,4-dihydroxybutoxy, —CH2Ra, —CH2CH2Rb, —(CH2)n—C(O)O—Rd, —(CH2)n—N(Rc)C(O)O—Rd, —O—(CH2)n—N(Rc)C(O)O—Rd, —(CH2)n—Re or —O—(CH2)n—Re; Ra is cyano, acetylamino or N,N-dimethylamino; Rb is cyano or carbamoyl; Rc is H or methyl; Rd is alkyl; Re is pyrrolidin-1-yl, piperidin-1-yl, piperidin-3-yl, morpholin-1-yl, 2-oxopyrrolidin-1-yl, 5-oxType: GrantFiled: March 28, 2012Date of Patent: November 18, 2014Assignee: Actelion Pharmaceuticals Ltd.Inventors: Markus Gude, Christian Hubschwerlen, Philippe Panchaud
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Publication number: 20140038961Abstract: The invention relates to 3-ureidoisoquinolin-8-yl derivatives of formula I wherein R1 is alkyl, haloalkyl or cyclopropyl; R2 is H, halogen, pyridazin-4-yl, pyrimidin-5-yl or an optionally substituted pyridin-3-yl, pyridin-4-yl or phenyl group; R3 is alkyl, alkynyl, aminoalkyl, carbamoylalkyl, methylcarbamoylalkyl, alkoxy, haloalkoxy, alkynyloxy, (4-hydroxybut-2-yn-1-yl)oxy, (4-aminobut-2-yn-1-yl)oxy, dimethylaminoalkoxy, carbamoylalkoxy, alkylamino, cycloalkyl, cycloalkylalkyl, cycloalkylalkoxy, hydroxyalkyl, hydroxyalkoxy, alkoxyalkyl, alkoxyalkoxy, carboxyalkyl, carboxyalkoxy, alkoxycarbonylalkoxy, aryl, heteroaryl, benzyl, benzyloxy, 2-cyanoethoxy, 2,3-dihydroxypropoxy, 3,4-dihydroxybutoxy, —CH2Ra, —CH2CH2Rb, —(CH2)n—C(O)O—Rd, —(CH2)n—N(Rc)C(O)O—Rd, —O—(CH2)n—N(Rc)C(O)O—Rd, —(CH2)n—Re or —O—(CH2)n—Re; Ra is cyano, acetylamino or N,N-dimethylamino; Rb is cyano or carbamoyl; Rc is H or methyl; Rd is alkyl; Re is pyrrolidin-1-yl, piperidin-1-yl, piperidin-3-yl, morpholin-1-yl, 2-oxopyrrolidin-1-yl, 5-oxType: ApplicationFiled: March 28, 2012Publication date: February 6, 2014Applicant: Actelion Pharmaceuticals Ltd.Inventors: Markus Gude, Christian Hubschwerlen, Philippe Panchaud
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Publication number: 20130096119Abstract: The invention relates to isoquinolin-3-ylurea derivatives of formula (I) wherein R1 represents (C1-C3)alkyl, (C1-C3)haloalkyl or cyclopropyl, R4 represents H and the substituents R2 and R3 and R5 have the meanings disclosed in the specification; and to the salts of such compounds. These compounds are useful for the prevention or the treatment of bacterial infections.Type: ApplicationFiled: March 30, 2011Publication date: April 18, 2013Inventors: Daniel Bur, Markus Gude, Christian Hubschwerlen, Philippe Panchaud
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Patent number: 8124623Abstract: The invention relates to novel chimeric antibiotics of formula I wherein R1 represents OH, OPO3H2 or OCOR5; R2 represents H, OH or OPO3H2; A represents N or CR6; R3 represents H or fluorine; R4 is H, (C1-C3) alkyl, or cycloalkyl; R5 is the residue of a naturally occurring amino acid, of the enantiomer of a naturally occurring amino acid or of dimethylaminoglycine; R6 represents H, alkoxy or halogen; and n is 0 or 1; and to salts (in particular pharmaceutically acceptable salts) of compounds of formula I. These chimeric compounds are useful in the manufacture of medicaments for the treatment of infections (e.g. bacterial infections).Type: GrantFiled: May 8, 2009Date of Patent: February 28, 2012Assignee: Actelion Pharmaceuticals Ltd.Inventors: Christian Hubschwerlen, Hans Locher, Philippe Panchaud, Jean-Luc Specklin
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Patent number: 8039466Abstract: The invention relates to novel chimeric antibiotics of formula I wherein R1 represents OH, OPO3H2 or OCOR5; R2 represents H, OH or OPO3H2; R3 represents H or halogen; R4 is H, (C1-C3)alkyl, or cycloalkyl; R5 represents piperidin-4-yl or R5 is the residue of a naturally occurring amino acid, of the enantiomer of a naturally occurring amino acid or of dimethylaminoglycine; n is 0 or 1; and to salts (in particular pharmaceutically acceptable salts) of compounds of formula I. These chimeric compounds are useful in the manufacture of medicaments for the treatment of infections (e.g. bacterial infections).Type: GrantFiled: November 23, 2007Date of Patent: October 18, 2011Assignee: Actelion Pharmaceutical Ltd.Inventors: Christian Hubschwerlen, Philippe Panchaud, Jean-Luc Specklin
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Publication number: 20100222302Abstract: The invention relates to novel chimeric antibiotics of formula I wherein R1 is CH2NHCOR5, heteroarylmethyl, heteroaryloxymethyl or heteroarylaminomethyl; R2 is H, OH, OSO3H, OPO3H2, OCH2OPO3H2, OCOCH2CH2COOH, OCOR6; R3 is H or halogen; R4 is (C1-C3)alkyl, (C1-C3)haloalkyl or cycloalkyl; R5 is alkyl or haloalkyl; and R6 is the residue of a naturally occurring amino acid or of dimethylaminoglycine. These chimeric compounds are useful in the manufacture of medicaments for the treatment of infections (e.g. bacterial infections).Type: ApplicationFiled: August 7, 2006Publication date: September 2, 2010Inventors: Christian Hubschwerlen, Philippe Panchaud, Christine Sigwalt, Jean-Luc Specklin
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Publication number: 20100069376Abstract: The invention relates to novel chimeric antibiotics of formula I wherein R1 represents OH, OPO3H2 or OCOR5; R2 represents H, OH or OPO3H2; R3 represents H or halogen; R4 is H, (C1-C3)alkyl, or cycloalkyl; R5 represents piperidin-4-yl or R5 is the residue of a naturally occurring amino acid, of the enantiomer of a naturally occurring amino acid or of dimethylaminoglycine; n is 0 or 1; and to salts (in particular pharmaceutically acceptable salts) of compounds of formula I. These chimeric compounds are useful in the manufacture of medicaments for the treatment of infections (e.g. bacterial infections).Type: ApplicationFiled: November 23, 2007Publication date: March 18, 2010Applicant: Actelion Pharmaceuticals, Ltd.Inventors: Christian Hubschwerlen, Philippe Panchaud, Jean-Luc Specklin
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Publication number: 20090247578Abstract: The invention relates to novel chimeric antibiotics of formula I wherein R1 represents OH, OPO3H2 or OCOR5; R2 represents H, OH or OPO3H2; A represents N or CR6; R3 represents H or fluorine; R4 is H, (C1-C3) alkyl, or cycloalkyl; R5 is the residue of a naturally occurring amino acid, of the enantiomer of a naturally occurring amino acid or of dimethylaminoglycine; R6 represents H, alkoxy or halogen; and n is 0 or 1; and to salts (in particular pharmaceutically acceptable salts) of compounds of formula I. These chimeric compounds are useful in the manufacture of medicaments for the treatment of infections (e.g. bacterial infections).Type: ApplicationFiled: May 8, 2009Publication date: October 1, 2009Applicant: Actelion Pharmaceuticals Ltd.Inventors: Christian HUBSCHWERLEN, Hans Locher, Philippe Panchaud, Jean-Luc Specklin