Patents by Inventor Philippe Patrick MONNIER

Philippe Patrick MONNIER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods, compounds and compositions for modulating blood brain barrier integrity and re-myelination
    Patent number: 10874712
    Abstract: Disclosed herein are methods and compositions for increasing and decreasing the permeability of the blood brain barrier for the treatment of diseases and conditions and to facilitate the delivery of agents to the brain, as well as methods and compositions for promoting re-myelination and preventing de-myelination. Compositions include RGMa, soluble RGMa, and functional fragments and variants thereof, RGMc, soluble RGMc, and functional fragments and variants thereof, and Neogenin peptides including 4Ig.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: December 29, 2020
    Assignee: UNIVERSITY HEALTH NETWORK
    Inventors: Philippe Patrick Monnier, Nardos G. Tassew, Yuriy Baglaenko
  • Methods, Compounds and Compositions for Modulating Blood Brain Barrier Integrity and Re-myelination
    Publication number: 20200016237
    Abstract: Disclosed herein are methods and compositions for increasing and decreasing the permeability of the blood brain barrier for the treatment of diseases and conditions and to facilitate the delivery of agents to the brain, as well as methods and compositions for promoting re-myelination and preventing de-myelination. Compositions include RGMa, soluble RGMa, and functional fragments and variants thereof, RGMc, soluble RGMc, and functional fragments and variants thereof, and Neogenin peptides including 4Ig.
    Type: Application
    Filed: July 31, 2019
    Publication date: January 16, 2020
    Inventors: Philippe Patrick MONNIER, Nardos G. TASSEW, Yuriy BAGLAENKO
  • Methods, compounds and compositions for modulating blood brain barrier integrity and re-myelination
    Patent number: 10398753
    Abstract: Disclosed herein are methods and compositions for increasing and decreasing the permeability of the blood brain barrier for the treatment of diseases and conditions and to facilitate the delivery of agents to the brain, as well as methods and compositions for promoting re-myelination and preventing de-myelination. Compositions include RGMa, soluble RGMa, and functional fragments and variants thereof, RGMc, soluble RGMc, and functional fragments and variants thereof, and Neogenin peptides including 4Ig.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: September 3, 2019
    Inventors: Philippe Patrick Monnier, Nardos G. Tassew, Yuriy Baglaenko
  • Methods, Compounds and Compositions for Modulating Blood Brain Barrier Integrity and Re-myelination
    Publication number: 20180250361
    Abstract: Disclosed herein are methods and compositions for increasing and decreasing the permeability of the blood brain barrier for the treatment of diseases and conditions and to facilitate the delivery of agents to the brain, as well as methods and compositions for promoting re-myelination and preventing de-myelination. Compositions include RGMa, soluble RGMa, and functional fragments and variants thereof, RGMc, soluble RGMc, and functional fragments and variants thereof, and Neogenin peptides including 4Ig.
    Type: Application
    Filed: September 23, 2016
    Publication date: September 6, 2018
    Inventors: Philippe Patrick MONNIER, Nardos G. TASSEW, Yuriy BAGLAENKO