Patents by Inventor Philippe Pflieger

Philippe Pflieger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anthranilamide and 2-amino-heteroarene-carboxamide compounds
    Patent number: 7678818
    Abstract: Compounds of formula I processes for their preparation, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: January 19, 2007
    Date of Patent: March 16, 2010
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Aurelia Conte, Holger Kuehne, Thomas Luebbers, Patrizio Mattei, Cyrille Maugeais, Werner Mueller, Philippe Pflieger
  • Heteroaryl and benzyl amide compounds
    Patent number: 7674815
    Abstract: Compounds of formula I processes for their preparation, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: January 29, 2007
    Date of Patent: March 9, 2010
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Christoph Faeh, Holger Kuehne, Thomas Luebbers, Patrizio Mattei, Cyrille Maugeais, Philippe Pflieger
  • CB 1 receptor inverse agonists
    Patent number: 7579369
    Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, m and X are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: August 25, 2009
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander Mayweg, Hans Peter Marty, Werner Mueller, Robert Narquizian, Werner Neidhart, Philippe Pflieger, Stephan Roever
  • Heteroaryl carboxamide compounds
    Patent number: 7572823
    Abstract: Compounds of formula I their manufacture, pharmaceutical compositions containing them and their use as medicaments.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: August 11, 2009
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Aurelia Conte, Holger Kuehne, Thomas Luebbers, Patrizio Mattei, Cyrille Maugeais, Werner Mueller, Philippe Pflieger
  • Heterocyclic cannabinoid receptor antagonists
    Patent number: 7563910
    Abstract: The present invention relates to compounds of formula I and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors.
    Type: Grant
    Filed: May 9, 2005
    Date of Patent: July 21, 2009
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander Mayweg, Robert Narquizian, Philippe Pflieger, Stephan Roever
  • GLUCOCORTICOID RECEPTOR ANTAGONISTS
    Publication number: 20090088425
    Abstract: The present invention relates to compounds of formula I wherein A, n, R1a to R1e and R2 to R5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression.
    Type: Application
    Filed: September 15, 2008
    Publication date: April 2, 2009
    Inventors: Jacques Bailly, Cornelia Hertel, Daniel Hunziker, Christian Lerner, Ulrike Obst Sander, Jens-Uwe Peters, Philippe Pflieger, Tanja Schulz-Gasch
  • PROCESS FOR THE PREPARATION OF INDOLE DERIVATIVES
    Publication number: 20090012311
    Abstract: A process for the preparation of indole derivatives of formula (I): which are useful as intermediates in the preparation of pharmaceutically active compounds.
    Type: Application
    Filed: June 25, 2008
    Publication date: January 8, 2009
    Inventors: Stephan Bachmann, Philippe Pflieger, Goesta Rimmler, Michelangelo Scalone
  • NEW INDOLE OR BENZIMIDAZOLE DERIVATIVES AS CB1 INVERSE AGONISTS
    Publication number: 20080234290
    Abstract: Provided are compounds of the formula I: and pharmaceutically acceptable salts thereof, processes for making said compounds and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising said compound and pharmaceutically acceptable salts thereof, and methods of using said compounds. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors.
    Type: Application
    Filed: May 2, 2008
    Publication date: September 25, 2008
    Inventors: Konrad Bleicher, Matthias Heinrich Nettekoven, Philippe Pflieger, Stephan Roever
  • Indole or benzimidazole derivatives as CB1 inverse agonists
    Patent number: 7384945
    Abstract: Provided are compounds of the formula I: and pharmaceutically acceptable salts thereof, processes for making said compounds and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising said compound and pharmaceutically acceptable salts thereof, and methods of using said compounds. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors.
    Type: Grant
    Filed: October 25, 2005
    Date of Patent: June 10, 2008
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Konrad Bleicher, Matthias Heinrich Nettekoven, Philippe Pflieger, Stephan Roever
  • CB 1 receptor inverse agonists
    Patent number: 7294644
    Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, m and X are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors.
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: November 13, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander Mayweg, Hans Peter Marty, Werner Mueller, Robert Narquizian, Werner Neidhart, Philippe Pflieger, Stephan Roever
  • Novel CB 1 receptor inverse agonists
    Publication number: 20070238754
    Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, m and X are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with the modulation of CB1 receptors.
    Type: Application
    Filed: May 10, 2007
    Publication date: October 11, 2007
    Inventors: Alexander Mayweg, Hans Marty, Werner Mueller, Robert Narquizian, Werner Neidhart, Philippe Pflieger, Stephan Roever
  • Anthranilamide and 2-amino-heteroarene-carboxamide compounds
    Publication number: 20070219261
    Abstract: Compounds of formula I processes for their preparation, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: January 19, 2007
    Publication date: September 20, 2007
    Inventors: Aurelia Conte, Holger Kuehne, Thomas Luebbers, Patrizio Mattei, Cyrille Maugeais, Werner Mueller, Philippe Pflieger
  • Thiazole derivatives
    Patent number: 7265109
    Abstract: Compounds of formula I as well as pharmaceutically acceptable salts and esters thereof, wherein the substituents have the significance given in the specification, and the compounds are neuropeptide Y(NPY) antagonists which are useful in the treatment of obesity.
    Type: Grant
    Filed: August 10, 2004
    Date of Patent: September 4, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger, Sven Taylor
  • Neuropeptide Y antagonists
    Patent number: 7265125
    Abstract: Quinoline and quinazoline derivatives can be used in the form of pharmaceutical preparations as Neuropeptide Y antagonists for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.
    Type: Grant
    Filed: April 7, 2005
    Date of Patent: September 4, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Volker Breu, Frank Dautzenberg, Philippe Guerry, Matthias Heinrich Nettekoven, Philippe Pflieger
  • Indole, indazole and indoline derivatives as CETP inhibitors
    Patent number: 7259183
    Abstract: The present invention relates to compounds of formula (I): wherein —X—Y—, R1 to R11 and n are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prevention of diseases which are mediated by CETP inhibitors.
    Type: Grant
    Filed: August 4, 2005
    Date of Patent: August 21, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Aurelia Conte-Mayweg, Holger Kuehne, Thomas Luebbers, Cyrille Maugeais, Werner Mueller, Philippe Pflieger
  • Heteroaryl and benzyl amide compounds
    Publication number: 20070185058
    Abstract: Compounds of formula I wherein R1, R2, R4, R5, A, B, D and n are as defined, and pharmaceutically acceptable salts thereof, processes for their preparation, their use as pharmaceuticals and pharmaceutical compositions comprising them.
    Type: Application
    Filed: January 25, 2007
    Publication date: August 9, 2007
    Inventors: Aurelia Conte, Holger Kuehne, Thomas Luebbers, Patrizio Mattei, Cyrille Maugeais, Werner Mueller, Philippe Pflieger
  • Heteroaryl carboxamide compounds
    Publication number: 20070185182
    Abstract: Compounds of formula I their manufacture, pharmaceutical compositions containing them and their use as medicaments.
    Type: Application
    Filed: January 26, 2007
    Publication date: August 9, 2007
    Inventors: Aurelia Conte, Holger Kuehne, Thomas Luebbers, Patrizio Mattei, Cyrille Maugeais, Werner Mueller, Philippe Pflieger
  • Heteroaryl and benzyl amide compounds
    Publication number: 20070185113
    Abstract: Compounds of formula I processes for their preparation, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: January 29, 2007
    Publication date: August 9, 2007
    Inventors: Christoph Faeh, Holger Kuehne, Thomas Luebbers, Patrizio Mattei, Cyrille Maugeais, Philippe Pflieger
  • Heterobicyclic amide compounds
    Publication number: 20070185154
    Abstract: Compounds of formula I processes for their preparation and pharmaceutical compositions comprising them.
    Type: Application
    Filed: January 19, 2007
    Publication date: August 9, 2007
    Inventors: Holger Kuehne, Thomas Luebbers, Patrizio Mattei, Cyrille Maugeais, Philippe Pflieger, Michelangelo Scalone
  • Aminothiazole derivatives
    Patent number: 7253197
    Abstract: Compounds of formula I as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R4 have the significance given in the specification, and the compounds, salts and esters can be used for the treatment of obesity.
    Type: Grant
    Filed: August 5, 2003
    Date of Patent: August 7, 2007
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Wolfgang Guba, Patrizio Mattei, Werner Neidhart, Matthias Heinrich Nettekoven, Philippe Pflieger