Patents by Inventor Philippe Pradelles

Philippe Pradelles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080248593
    Abstract: The present invention relates to a method for detecting and/or measuring the concentration of fluoride (F?) or hydrogen fluoride (HF) in a sample, comprising the steps consisting of bringing said sample, in aqueous solution, into contact with a silylated organic compound in order to obtain a measurement solution, with said silylated organic compound being desilylated when it is in the presence of hydrofluoric acid or a fluoride, with the silylated organic compound and the desilylated organic compound being able to be detected and/or measured separately from each other; and detecting and/or measuring, in said measurement solution, the appearance of the desilylated against compound or the disappearance of the silylated organic compound, which takes place if fluoride or hydrogen fluoride is present in the sample. The method enables the presence of hydrogen fluoride or of fluorine to be detected very easily and expediently at concentrations of 10?2 l of HF/106 l of air (10 ppb) or else of 0.
    Type: Application
    Filed: June 17, 2008
    Publication date: October 9, 2008
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE
    Inventors: Eric Ezan, Marie-Astrid Sagot, Philippe Pradelles
  • Patent number: 7396691
    Abstract: The present invention relates to a method for detecting and/or measuring the concentration of fluoride (F?) or hydrogen fluoride (HF) in a sample, comprising the steps consisting of bringing said sample, in aqueous solution, into contact with a silylated organic compound in order to obtain a measurement solution, with said silylated organic compound being desilylated when it is in the presence of hydrofluoric acid or a fluoride, with the silylated organic compound and the desilylated organic compound being able to be detected and/or measured separately from each other; and detecting and/or measuring, in said measurement solution, the appearance of the desilylated against compound or the disappearance of the silylated organic compound, which takes place if fluoride or hydrogen fluoride is present in the sample. The method enables the presence of hydrogen fluoride or of fluorine to be detected very easily and expediently at concentrations of 10?2 l of HF/106 l of air (10 ppb) or else of 0.
    Type: Grant
    Filed: May 14, 2004
    Date of Patent: July 8, 2008
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Eric Ezan, Marie-Astrid Sagot, Philippe Pradelles
  • Publication number: 20050227368
    Abstract: The present invention relates to a method for detecting and/or measuring the concentration of fluoride (F?) or hydrogen fluoride (HF) in a sample, comprising the steps consisting of bringing said sample, in aqueous solution, into contact with a silylated organic compound in order to obtain a measurement solution, with said silylated organic compound being desilylated when it is in the presence of hydrofluoric acid or a fluoride, with the silylated organic compound and the desilylated organic compound being able to be detected and/or measured separately from each other; and detecting and/or measuring, in said measurement solution, the appearance of the desilylated against compound or the disappearance of the silylated organic compound, which takes place if fluoride or hydrogen fluoride is present in the sample. The method enables the presence of hydrogen fluoride or of fluorine to be detected very easily and expediently at concentrations of 10?2 l of HF/106 l of air (10 ppb) or else of 0.
    Type: Application
    Filed: May 14, 2004
    Publication date: October 13, 2005
    Inventors: Eric Ezan, Marie-Astrid Sagot, Philippe Pradelles
  • Patent number: 5476770
    Abstract: The invention relates to a process for the immunometric determination of an antigen or hapten.According to this process, contacting takes place (FIG. 1A) between the antigen or hapten (3) to be determined and the antibodies (2) fixed to a solid phase in order to immunologically bond the antigen or hapten with the antibody. This is followed (FIG. 1B) by immobilizing the antigen or hapten (3) by a covalent bond (4) to the solid phase (1) whilst releasing its epitope (FIG. 1C). This is followed by the contacting thereof (FIG. 1D) with labelled antibodies (5) and determination takes place (FIG. 1E) of the quantity of fixed labelled antibodies in order to deduce therefrom the initial hapten or antigen concentration.As a result of this stage of immobilizing and releasing the epitope, a high sensitivity is obtained using a single antibody.
    Type: Grant
    Filed: January 24, 1994
    Date of Patent: December 19, 1995
    Assignee: Commissariat A L'Energie Atomique
    Inventor: Philippe Pradelles
  • Patent number: 5047330
    Abstract: Compound labelled by the acetyl cholinesterase of Electrophorus electricus, its preparation process and its use in enzymoimmunology.This compound is constituted by a molecule chosen from among the antigens, haptens and antibodies, bonded by a covalent bond to an enzyme formed by the acetyl cholinesterase of Electrophorus electricus (electric eel).For example, the molecule is the substance P or a prostaglandin and the compound can be used for the enzymoimmunological determination of these molecules.
    Type: Grant
    Filed: January 6, 1988
    Date of Patent: September 10, 1991
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Jacques Grassi, Philippe Pradelles