Abstract: Pharmacologically valuable esters of isobutyric acid have the general formula ##STR1## in which R is biphenylyl, norbornyl or para-cyclohexylphenyl and R.sup.1 and R.sup.2 are each lower alkyl groups or R.sup.1 and R.sup.2 together with the nitrogen atom to which they are linked is a saturated heterocyclic group which may contain an additional hetero atom. The esters may be used in the form of their salts with pharmaceutically acceptable acids.The esters and their salts possess spasmolytic and vasodilatory activity and are useful in the treatment of arterial disorders.

Abstract: Hydrosoluble salts of paracetamol with an amine, in particular with a piperazine represented by the formula:- ##SPC1##(in which R.sub.1 and R.sub.2, which may be the same or different, are each a hydrogen atom or a lower alkyl group), and pharmaceutical compositions containing at least one of these salts as active ingredient in association with a physiologically acceptable aqueous medium, for example in orally administrable forms, such as effervescent compounds, soluble powders, syrups, or in parenterally administrable forms, such as injectable solutions, making it possible to administer high doses of paracetamol in aqueous solution.