Patents by Inventor Philippe Rott

Philippe Rott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Albicidin derivatives, their use and synthesis
    Patent number: 10308595
    Abstract: Antibiotically active compounds characterized by general formula (I), wherein X1, BB, BC, BD, BE and X2 are building blocks with D1, D2, D3, D4 or D5 being linkers which include carbon, sulphur, nitrogen, phosphor and/or oxygen atoms and which are covalently connecting the moities BA and BB, BB and BC, BC and BD, BD and BE and BE and BF, respectively, and wherein in particular the building block BC comprises an amino acid derivative. The compounds for use in a method of treatment of diseases, in particular for use in a method of treatment of bacterial infections are also disclosed.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: June 4, 2019
    Assignee: TECHNISCHE UNIVERSITÄT BERLIN
    Inventors: Roderich Suessmuth, Julian Kretz, Vivien Schubert, Alexander Pesic, Manuela Huegelland, Monique Royer, Stephane Cociancich, Philippe Rott, Dennis Kerwat, Stefan Graetz
  • ALBICIDIN DERIVATIVES, THEIR USE AND SYNTHESIS
    Publication number: 20150376120
    Abstract: Antibiotically active compounds characterized by general formula (I), wherein X1, BB, BC, BD, BE and X2 are building blocks with D1, D2, D3, D4 or D5 being linkers which include carbon, sulphur, nitrogen, phosphor and/or oxygen atoms and which are covalently connecting the moities BA and BB, BB and BC, BC and BD, BD and BE and BE and BF, respectively, and wherein in particular the building block BC comprises an amino acid derivative. The compounds for use in a method of treatment of diseases, in particular for use in a method of treatment of bacterial infections are also disclosed.
    Type: Application
    Filed: February 14, 2014
    Publication date: December 31, 2015
    Inventors: Roderich SÜSSMUTH, Julian KRETZ, Vivien SCHUBERT, Alexander PESIC, Manuela HÜGELLAND, Monique ROYER, Stéphane COCIANCICH, Philippe ROTT, Dennis KERWAT, Stefan GRÄTZ
  • Biosynthetic genes and host cells for the synthesis of polyketide antibiotics and method of use
    Patent number: 7510852
    Abstract: Three gene clusters that together encode albicidin biosynthesis, the complete gene DNA sequences, and the deduced protein sequences for the enzymes and methods for using the DNA sequences are disclosed and discussed as well as methods for plant protection and creating new antibiotics. The novel Albicidin family of antibiotics is disclosed and their structure deduced.
    Type: Grant
    Filed: October 17, 2003
    Date of Patent: March 31, 2009
    Assignees: Centre de Cooperation Internationale en Recherche Agronomique pour le Developpement (CIRAD), University of Florida Research Foundation, Inc.
    Inventors: Monique Royer, Dean W. Gabriel, Roger Frutos, Philippe Rott
  • Complete biosynthetic gene set for synthesis of polyketide antibiotics, including the albicidin family, resistance genes, and uses thereof
    Publication number: 20060269988
    Abstract: Three gene clusters that together encode albicidin biosynthesis, the complete gene DNA sequences, and the deduced protein sequences for the enzymes and methods for using the DNA sequences are disclosed and discussed as well as methods for plant protection and creating new antibiotics. The novel Albicidin family of antibiotics is disclosed and their structure deduced.
    Type: Application
    Filed: October 17, 2003
    Publication date: November 30, 2006
    Applicants: University of Florida Research Foundation, Inc., Centre de Cooperation Internationale en Recherche
    Inventors: Monique Royer, Dean Gabriel, Roger Frutos, Philippe Rott