Patents by Inventor Philippe Samama

Philippe Samama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Site-specific bioconjugates of chemokines and their use in assays
    Patent number: 6156520
    Abstract: The present invention encompasses polypeptides that comprise a chemokine receptor binding sequence and are useful in determining the affinity of a compound for a chemokine receptor. Substitution of one of the amino acids of the C-terminal region of the polypeptide with a cysteine enables the polypeptide to be detectably labelled without loss of receptor binding activity and without the problems inherent in radioiodine labelling. Methods for use of the polypeptides in competitive binding assays are also disclosed.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: December 5, 2000
    Assignee: Pharmacopeia, Inc.
    Inventors: James Inglese, Kenneth C. Appell, Philippe Samama, Ilana L. Stroke, Jonathan J. Burbaum