Patents by Inventor Philippe Stas

Philippe Stas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8571806
    Abstract: The present invention provides methods for generating information related to the molecular structure of a biomolecule.
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: October 29, 2013
    Assignee: Lonza Biologies PLC
    Inventors: Johan Desmet, Ignace Lasters, Dominique Vlieghe, Carlo Boutton, Philippe Stas, Jan Spriet
  • Publication number: 20130013279
    Abstract: The present invention provides methods and apparatus for analyzing a protein structure.
    Type: Application
    Filed: May 15, 2012
    Publication date: January 10, 2013
    Applicant: Lonza Biologics plc
    Inventors: Johan Desmet, Ignace Lasters, Dominique Vlieghe, Carlo Boutton, Philippe Stas
  • Patent number: 8229721
    Abstract: The invention provides methods and apparatus for analyzing a protein structure by A) receiving a reference structure (A) forming a three dimensional representation of a protein; B) substituting into the structure of (A) a pattern with amino-acids different from the one of the protein; C) optimizing the conformation of (A) substituted by pattern of (B); D) assessing the energetic compatibility (EC) of the pattern of (B) within the context of the structure of (A) being structurally optimized in (C) with respect to the pattern, by comparing the global energy of the substituted and optimized protein structure with the global energy of the non-substituted reference structure; and E) storing a value reflecting the EC of the pattern together with information related to the structure of the pattern in the form of an energetic compatibility object (ECO).
    Type: Grant
    Filed: November 3, 2000
    Date of Patent: July 24, 2012
    Assignee: Lonza Biologics plc
    Inventors: Johan Desmet, Ignace Lasters, Dominique Vlieghe, Carlo Boutton, Philippe Stas
  • Publication number: 20110137617
    Abstract: A method for generating information related to the molecular structure of a biomolecule, comprising the steps of: (a) receiving a three-dimensional representation of said molecular structure, comprising a first set of residue portions and a template; and (b) modifying the representation of step (a) by at least one optimization cycle.
    Type: Application
    Filed: December 2, 2010
    Publication date: June 9, 2011
    Inventors: Johan DESMET, Ignace Lasters, Dominique Vlieghe, Carlo Boutton, Philippe Stas, Jan Spriet