Patents by Inventor Philippe Touraine

Philippe Touraine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONSTITUTIVELY ACTIVE PROLACTIN RECEPTOR VARIANTS AS PROGNOSTIC MARKERS AND THERAPEUTIC TARGETS TO PREVENT PROGRESSION OF HORMONE-DEPENDENT CANCERS TOWARDS HORMONE-INDEPENDENCE
    Publication number: 20130244936
    Abstract: The present invention relates to an in vitro method of prognosing outcome of hormone-dependent cancer in a subject comprising detecting a constitutively activating mutation in the prolactin receptor (PRLR) gene in a nucleic acid sample previously obtained from said subject, said constitutively activating mutation being preferably a mutation resulting in the expression of a mutant prolactin receptor wherein the isoleucine residue at position 146 is substituted with leucine or a mutation resulting in the expression of a mutant prolactin receptor wherein the isoleucine residue at position 76 is substituted with valine.
    Type: Application
    Filed: June 1, 2011
    Publication date: September 19, 2013
    Inventors: Vincent Goffin, Sophie Bernichtein, Isabelle Fernandez, Philippe Touraine
  • Constitutively active mutants of the prolactin receptor
    Patent number: 8263340
    Abstract: The invention relates to constitutively active mutants of the prolactin receptor (PRLR), wherein an Ile residue at position 76 or at position 146 of the mature form of said receptor has been substituted by another amino acid residue. The invention also provides methods useful for the diagnosis, prognosis, or treatment of diseases involving the PRLR.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: September 11, 2012
    Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Vincent Goffin, Philippe Touraine
  • CONSTITUTIVELY ACTIVE MUTANTS OF THE PROLACTIN RECEPTOR
    Publication number: 20100240033
    Abstract: The invention relates to constitutively active mutants of the prolactin receptor (PRLR), wherein an Ile residue at position 76 or at position 146 of the mature form of said receptor has been substituted by another amino acid residue. The invention also provides methods useful for the diagnosis, prognosis, or treatment of diseases involving the PRLR.
    Type: Application
    Filed: March 20, 2007
    Publication date: September 23, 2010
    Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (INSERM)
    Inventors: Vincent Goffin, Philippe Touraine