Abstract: The present invention relates to a polysaccharide complex comprising at least one polysaccharide (P1) and ii) a heterologous lipid carrier wherein the heterologous lipid carrier comprises a) a lipid portion comprising at least one ceramide-like glycolipid moiety and/or a fatty acid moiety and b) at least one non-lipid moiety, preferably said non-lipid portion comprises at least one carbohydrate moiety, at least one lipopeptide moiety, at least one linker, at least one chemical compound, and/or at least one peptide moiety, wherein i) and ii) are associated. Further, the invention is directed to a method to prepare said polysaccharide complex.

Abstract: The present invention relates to modified non-pathogenic microorganisms (e g bacteria, yeasts or fungi) comprising a cell and a heterologous lipid carrier, wherein said lipid carrier comprises a) a lipid portion, wherein said lipid portion is at least partially associated with an exterior surface of said cell of said modified microorganism and wherein said lipid portion comprises a ceramide-like glycolipid moiety and/or a fatty acid moiety, and wherein said lipid carrier further comprises b) a non-lipid portion, wherein said microorganism is capable of locating and/or displaying said non-lipid portion or fragment thereof onto the exterior surface of said cell, wherein said cell of said modified microorganism does not comprise a mycomembrane and wherein said heterologous lipid carrier is not alpha-galactosylceramide.

Abstract: The present invention relates to means and method for isolating naturally-occurring microorganisms (non-pathogenic bacteria, yeasts or fungi) capable of binding toxins from microorganisms such as bacteria, viruses, fungi, yeasts, or protozoans and/or receptors for these toxins on the surface of mammalian cells, thereby making these receptors inaccessible for said toxins. The naturally-occurring microorganisms that are obtainable by the means and methods of the present invention can be used for adsorbing toxins from pathogenic microorganisms and/or blocking receptors for such toxins on the surface of mammalian cells. These toxin-receptor interactions are known to be critical for disease pathogenesis, making both the toxins and receptors a target for the naturally-occurring microorganisms of the present invention.

Abstract: The present invention pertains to microorganisms of the species Bacteroides xylanisolvens expressing a core-1 antigen on their surface. These microorganisms are in particular useful for the prophylaxis and treatment of core-1 positive diseases and are particularly characterized by a stable, homogenous high core-1 expression. Also provided are pharmaceutical compositions which comprise respective core-1 positive microorganisms or fractions thereof.

Abstract: The present invention pertains to food products comprising microorganisms of the species Bacteroides xylanisolvens, in particular fermented food and probiotic food. These microorganisms are particularly characterized as having a very low pathogenicity and a high safety for human consumption. Furthermore, methods for producing said food products, in particular by fermentation, as well as suitable bacterial strains Bacteroides xylanisolvens of are provided.

Abstract: The present invention pertains to microorganisms of the species Bacteroides xylanisolvens expressing a core-1 antigen on their surface. These microorganisms are in particular useful for the prophylaxis and treatment of core-1 positive diseases and are particularly characterized by a stable, homogenous high core-1 expression. Also provided are pharmaceutical compositions which comprise respective core-1 positive microorganisms or fractions thereof.

Abstract: The present disclosure relates in one embodiment to a method of producing a fermented food, wherein a raw food material is combined with a starter culture for fermentation, wherein at least one microorganism of the genus Bacteroides and/or at least one microorganism having at least a cell surface structure which corresponds to a human carbohydrate structure is added. Further disclosed are processing aids and fermented foods containing respective microorganisms.

Abstract: The present invention relates to the field of prevention and treatment of disorders associated with the occurrence of certain carbohydrate epitopes. The present invention relates to the prevention and treatment of carbohydrate epitope positive tumors. The invention relates to formulations and methods for the induction of an effective carbohydrate specific cellular immune response.

Abstract: The present invention relates to the field of prevention and treatment of disorders associated with the occurrence of certain carbohydrate epitopes. The present invention relates to the prevention and treatment of carbohydrate epitope positive tumors. The invention relates to formulations and methods for the induction of an effective carbohydrate specific cellular immune response.