Patents by Inventor Phillip A. Beachy

Phillip A. Beachy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF FK506 FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION
    Publication number: 20190091208
    Abstract: A method for reducing pulmonary hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering FK506 to a mammal having pulmonary arterial hypertension associated with defective MBPR2 signaling at a dosage sufficient to reduce blood pressure in the pulmonary artery of the mammal.
    Type: Application
    Filed: November 21, 2018
    Publication date: March 28, 2019
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Edda SPIEKERKOETTER, Marlene Rabinovitch, Phillip A. Beachy, David Solow-Cordero
  • Method for identifying a hedgehog-mediated phosphorylation state dependent transcription factor
    Patent number: 6277566
    Abstract: The present invention provides transcription factors associated with the hedgehog signaling pathway that are regulated by dephosphorylation by phosphatases. Hedgehog response elements (HRE) that interact with the dephosphorylated transcription factors are also provided as well as methods for identifying compounds that are phosphatase inhibitors. Methods of treating tumors in a subject by modulating the phosphorylation of the transcription factor are also included.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: August 21, 2001
    Inventors: Phillip A. Beachy, Ming-Jer Tsai, Sophia Y. Tsai, Venkatesh Krishnan, Chen-Huan Chen