Patents by Inventor Phillip A. Haywood

Phillip A. Haywood has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITIONS COMPRISING RPL554 IN HFA-134A FOR ADMINISTRATION BY INHALATION
    Publication number: 20210379053
    Abstract: The present invention relates to a liquid pharmaceutical composition suitable for administration by inhalation comprising: (i) a suspension of particles comprising 9,10-dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one (RPL554); and (ii) a diluent which is 1,1,1,2-tetrafluoroethane (HFA-134a), wherein the liquid pharmaceutical composition is substantially free of surfactant. The invention also relates to a pressurised metered dose inhaler comprising the liquid pharmaceutical composition.
    Type: Application
    Filed: October 9, 2019
    Publication date: December 9, 2021
    Inventors: Peter Lionel SPARGO, Phillip A. HAYWOOD
  • Liquid inhalation formulation comprising RPL554
    Patent number: 10945950
    Abstract: The present invention relates to a liquid pharmaceutical composition suitable for administration by inhalation which comprises a diluent and a suspension of particles of 9,10-dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one (RPL554) or a pharmaceutically acceptable salt thereof. Also described is a liquid pharmaceutical composition according to the invention for use in the treatment of the human or animal body.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: March 16, 2021
    Assignee: VERONA PHARMA PLC
    Inventors: Peter Lionel Spargo, Edward James French, Phillip A. Haywood
  • Dry powder inhaler compositions of 7-azoniabicyclo[2.2.1]heptane derivatives
    Patent number: 10835514
    Abstract: Pharmaceutical compositions of muscarinic acetylcholine receptor antagonists suitable for administration via a dry powdered inhaler and methods of using the compositions for treating respiratory disease are provided.
    Type: Grant
    Filed: January 7, 2017
    Date of Patent: November 17, 2020
    Assignee: THERON PHARMACEUTICALS, INC.
    Inventors: Meenakshi S. Venkatraman, Xiaoming Zhang, Phillip Haywood
  • DRY POWDER INHALER COMPOSITIONS OF 7-AZONIABICYCLO[2.2.1]HEPTANE DERIVATIVES
    Publication number: 20190298690
    Abstract: Pharmaceutical compositions of muscarinic acetylcholine receptor antagonists suitable for administration via a dry powdered inhaler and methods of using the compositions for treating respiratory disease are provided.
    Type: Application
    Filed: January 7, 2017
    Publication date: October 3, 2019
    Inventors: Meenakshi S. VENKATRAMAN, Xiaoming ZHANG, Phillip HAYWOOD
  • LIQUID INHALATION FORMULATION COMPRISING RPL554
    Publication number: 20180369139
    Abstract: The present invention relates to a liquid pharmaceutical composition suitable for administration by inhalation which comprises a diluent and a suspension of particles of 9,10-dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one (RPL554) or a pharmaceutically acceptable salt thereof. Also described is a liquid pharmaceutical composition according to the invention for use in the treatment of the human or animal body.
    Type: Application
    Filed: March 21, 2018
    Publication date: December 27, 2018
    Inventors: Peter Lionel Spargo, Edward James French, Phillip A. Haywood
  • Liquid inhalation formulation comprising RPL554
    Patent number: 9956171
    Abstract: The present invention relates to a liquid pharmaceutical composition suitable for administration by inhalation which comprises a diluent and a suspension of particles of 9,10-dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one (RPL554) or a pharmaceutically acceptable salt thereof. Also described is a liquid pharmaceutical composition according to the invention for use in the treatment of the human or animal body.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: May 1, 2018
    Assignee: VERONA PHARMA PLC
    Inventors: Peter Lionel Spargo, Edward James French, Phillip A. Haywood
  • LIQUID INHALATION FORMULATION COMPRISING RPL554
    Publication number: 20170239178
    Abstract: The present invention relates to a liquid pharmaceutical composition suitable for administration by inhalation which comprises a diluent and a suspension of particles of 9,10-dimethoxy-2-(2,4,6-trimethylphenylimino)-3-(N-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one (RPL554) or a pharmaceutically acceptable salt thereof. Also described is a liquid pharmaceutical composition according to the invention for use in the treatment of the human or animal body.
    Type: Application
    Filed: September 15, 2015
    Publication date: August 24, 2017
    Inventors: Peter Lionel Spargo, Edward James French, Phillip A. Haywood