Patents by Inventor Phillip A. Patten
Phillip A. Patten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250031680Abstract: Systems and methods for sorting and imaging insects, including egg and larval life stages, useful for automated high throughput bioassays.Type: ApplicationFiled: October 14, 2024Publication date: January 30, 2025Inventors: Michael Freeman, Kathleen Marie Harding, Jingtong Hou, Bumshick Robert Pak, Phillip A. Patten, Lindsey Della Wiemer, Takashi Yamamoto
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Publication number: 20240400555Abstract: A method of modulating c-MYC activity is disclosed.Type: ApplicationFiled: April 26, 2024Publication date: December 5, 2024Applicant: Initial Therapeutics, Inc.Inventors: Phillip A. Patten, Jim Li, Brooke Olson Blair, Pingyu Ding, Yi Chiao Fan, Margot Paulick, Martin Linsell
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Patent number: 12144327Abstract: Systems and methods for sorting and imaging insects, including egg and larval life stages, useful for automated high throughput bioassays.Type: GrantFiled: July 10, 2023Date of Patent: November 19, 2024Assignee: Pioneer Hi-Bred International, Inc.Inventors: Michael Freeman, Kathleen Marie Harding, Jingtong Hou, Bumshik Robert Pak, Phillip A. Patten, Lindsey Della Wiemer, Takashi Yamamoto
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Publication number: 20230345921Abstract: Systems and methods for sorting and imaging insects, including egg and larval life stages, useful for automated high throughput bioassays.Type: ApplicationFiled: July 10, 2023Publication date: November 2, 2023Inventors: Michael Freeman, Kathleen Marie Harding, Jingtong Hou, Bumshik Robert Pak, Phillip A. Patten, Lindsey Della Wiemer, Takashi Yamamoto
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Patent number: 11730152Abstract: The present embodiments of the invention generally relate to methods for sorting and imaging insects, including egg and larval life stages, useful for automated high throughput bioassays.Type: GrantFiled: November 3, 2020Date of Patent: August 22, 2023Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Michael Freeman, Kathleen Marie Harding, Jingtong Hou, Bumshik Robert Pak, Phillip A Patten, Lindsey Della Wiemer, Takashi Yamamoto
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Patent number: 11697821Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: October 15, 2021Date of Patent: July 11, 2023Inventors: Ruth Cong, Jingtong Hou, Zhenglin Hou, Phillip A Patten, Takashi Yamamoto
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Publication number: 20230125600Abstract: Compositions and methods comprising polynucleotides and polypeptides having EPSP (5-enolpyruvylshikimate-3-phosphate) synthase (EPSPS) activity are provided. In specific embodiments, the sequence has an improved property, such as, but not limited to, improved catalytic capacity in the presence of the inhibitor, glyphosate. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the EPSPS sequences. Various methods of employing the EPSPS sequences are provided. Such methods include methods for producing a glyphosate tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein.Type: ApplicationFiled: December 9, 2022Publication date: April 27, 2023Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: YUXIA DONG, MICHAEL LASSNER, JIAN LU, EMILY NG, PHILLIP A PATTEN, DANIEL SIEHL
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Patent number: 11549123Abstract: Compositions and methods comprising polynucleotides and polypeptides having EPSP (5-enolpyruvylshikimate-3-phosphate) synthase (EPSPS) activity are provided. In specific embodiments, the sequence has an improved property, such as, but not limited to, improved catalytic capacity in the presence of the inhibitor, glyphosate. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the EPSPS sequences. Various methods of employing the EPSPS sequences are provided. Such methods include methods for producing a glyphosate tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein.Type: GrantFiled: March 12, 2020Date of Patent: January 10, 2023Inventors: Yuxia Dong, Michael Lassner, Jian Lu, Emily Ng, Phillip A Patten, Daniel Siehl
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Publication number: 20220389445Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: June 7, 2022Publication date: December 8, 2022Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: DAVID CHARLES CERF, JAMES J ENGLISH, CAROL A HENDRICK, LU LIU, JARRED KENNETH ORAL, PHILLIP A PATTEN, BARBARA ROSEN, UTE SCHELLENBERGER, INGRID UDRANSZKY, JUN-ZHI WEI, GENHAI ZHU
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Publication number: 20220177900Abstract: Compositions and methods are provided for genome modification of a target sequence in the genome of a cell. The methods and compositions employ a guide polynucleotide/Cas endonuclease system to provide an effective system for modifying or altering target sites within the genome of a cell or organism. Once a genomic target site is identified, a variety of methods can be employed to further modify the target sites such that they contain a variety of polynucleotides of interest. Compositions and methods are also provided for editing a nucleotide sequence in the genome of a cell. Breeding methods and methods for selecting plants utilizing a two component RNA polynucleotide and Cas endonuclease system are also disclosed.Type: ApplicationFiled: February 22, 2022Publication date: June 9, 2022Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: ANDREW MARK CIGAN, PHILLIP A PATTEN, JOSHUA K YOUNG
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Publication number: 20220025393Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: October 15, 2021Publication date: January 27, 2022Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: RUTH CONG, JINGTONG HOU, ZHENGLIN HOU, PHILLIP A. PATTEN, TAKASHI YAMAMOTO
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Publication number: 20210388377Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: June 18, 2021Publication date: December 16, 2021Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: RUTH CONG, JINGTONG HOU, ZHENGLIN HOU, PHILLIP A PATTEN, TAKASHI YAMAMOTO
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Patent number: 11180775Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: January 13, 2020Date of Patent: November 23, 2021Inventors: Ruth Cong, Jingtong Hou, Zhenglin Hou, Phillip A Patten, Takashi Yamamoto
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Patent number: 11091771Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: May 8, 2019Date of Patent: August 17, 2021Inventors: Ruth Cong, Jingtong Hou, Zhenglin Hou, Phillip A. Patten, Takashi Yamamoto
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Patent number: 11015206Abstract: Compositions and methods comprising polynucleotides and polypeptides having 4-hydroxyphenylpyruvate dioxygenase (HPPD) activity and having insensitivity to an HPPD inhibitor are provided. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the HPPD sequences. Various methods of employing the HPPD sequences are provided. Such methods include, for example, methods for producing an HPPD inhibitor tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional HPPD variants. Further provided are various methods and compositions that allow the various HPPD polypeptides and variant and fragments thereof to be expressed in a chloroplast or transported to a chloroplast.Type: GrantFiled: May 7, 2019Date of Patent: May 25, 2021Inventors: Phillip A Patten, Daniel Siehl, Yumin Tao, Henrik Albert, Ericka Bermudez, Linda A Castle, Yuxia Dong, Andrew Duncan Satterfield
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Publication number: 20200270630Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: March 9, 2020Publication date: August 27, 2020Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: DAVID CHARLES CERF, JAMES J ENGLISH, CAROL A HENDRICK, LU LIU, JARRED KENNETH ORAL, PHILLIP A PATTEN, BARBARA ROSEN, UTE SCHELLENBERGER, INGRID UDRANSZKY, JUN-ZHI WEI, GENHAI ZHU
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Publication number: 20200263193Abstract: Compositions and methods comprising polynucleotides and polypeptides having EPSP (5-enolpyruvylshikimate-3-phosphate) synthase (EPSPS) activity are provided. In specific embodiments, the sequence has an improved property, such as, but not limited to, improved catalytic capacity in the presence of the inhibitor, glyphosate. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the EPSPS sequences. Various methods of employing the EPSPS sequences are provided. Such methods include methods for producing a glyphosate tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein.Type: ApplicationFiled: March 12, 2020Publication date: August 20, 2020Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: YUXIA DONG, MICHAEL LASSNER, JIAN LU, EMILY NG, PHILLIP A PATTEN, DANIEL SIEHL
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Patent number: 10655143Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: May 23, 2017Date of Patent: May 19, 2020Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: David C. Cerf, James J. English, Carol A. Hendrick, Lu Liu, Jarred K. Oral, Phillip A. Patten, Barbara A. Rosen, Ute Schellenberger, Ingrid Udranszky, Jun-Zhi Wei, Genhai Zhu
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Patent number: 10655141Abstract: Compositions and methods comprising polynucleotides and polypeptides having EPSP (5-enolpyruvylshikimate-3-phosphate) synthase (EPSPS) activity are provided. In specific embodiments, the sequence has an improved property, such as, but not limited to, improved catalytic capacity in the presence of the inhibitor, glyphosate. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the EPSPS sequences. Various methods of employing the EPSPS sequences are provided. Such methods include methods for producing a glyphosate tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein.Type: GrantFiled: September 29, 2016Date of Patent: May 19, 2020Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Yuxia Dong, Michael Lassner, Jian Lu, Emily Ng, Phillip A. Patten, Daniel Siehl
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Publication number: 20200131529Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: January 13, 2020Publication date: April 30, 2020Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: RUTH CONG, JINGTONG HOU, ZHENGLIN HOU, PHILLIP A PATTEN, TAKASHI YAMAMOTO