Abstract: A method for determining the biological age or pace of aging of an adult dog, said method comprising determining the levels of one or more biomarkers selected from the group consisting of (1) blood globulin levels, (2) blood total protein, (3) blood alkaline phosphatase, (4) blood platelet count, (5) blood mean corpuscular volume or (6) urine specific gravity, comparing the results with values obtained from healthy dogs of a known age and of a similar category (toy, small, medium, large or giant). Kits, systems and/or computer media for carrying out the method form further aspects of the invention.

Abstract: A method for determining the biological age or pace of aging of an adult dog, said method comprising determining the levels of one or more biomarkers selected from the group consisting of (1) blood globulin levels, (2) blood total protein, (3) blood alkaline phosphatase, (4) blood platelet count, (5) blood mean corpuscular volume or (6) urine specific gravity, comparing the results with values obtained from healthy dogs of a known age and of a similar category (toy, small, medium, large or giant). Kits, systems and/or computer media for carrying out the method form further aspects of the invention.

Abstract: A method for determining the biological age or pace of aging of an adult dog, said method comprising determining the levels of one or more biomarkers selected from the group consisting of (1) blood globulin levels, (2) blood total protein, (3) blood alkaline phosphatase, (4) blood platelet count, (5) blood mean corpuscular volume or (6) urine specific gravity, comparing the results with values obtained from healthy dogs of a known age and of a similar category (toy, small, medium, large or giant). Kits, systems and/or computer media for carrying out the method form further aspects of the invention.

Abstract: The present disclosure relates to compositions comprising a range of ingredients suitable for use in adjusting and/or treating a companion animal such as a canid (e.g. a dog) or a feline (e.g. a cat) and their microbiomes, monitoring tools, and diagnostic methods for determining the health of a companion animal and their microbiome.

Abstract: A method for determining the biological age or pace of aging of an adult dog, said method comprising determining the levels of one or more biomarkers selected from the group consisting of (1) blood globulin levels, (2) blood total protein, (3) blood alkaline phosphatase, (4) blood platelet count, (5) blood mean corpuscular volume or (6) urine specific gravity, comparing the results with values obtained from healthy dogs of a known age and of a similar category (toy, small, medium, large or giant). Kits, systems and/or computer media for carrying out the method form further aspects of the invention.

Abstract: A method for determining the biological age or pace of aging of an adult dog, said method comprising determining the levels of one or more biomarkers selected from the group consisting of (1) blood globulin levels, (2) blood total protein, (3) blood alkaline phosphatase, (4) blood platelet count, (5) blood mean corpuscular volume or (6) urine specific gravity, comparing the results with values obtained from healthy dogs of a known age and of a similar category (toy, small, medium, large or giant). Kits, systems and/or computer media for carrying out the method form further aspects of the invention.

Abstract: Methods for assessing the health of the microbiome and compositions and food products for improving intestinal health, treating intestinal dysbiosis, and/or treating an intestinal disorder in a companion animal, e.g., a dog are provided.

Abstract: Methods for assessing a canid's microbiome health are provided. The methods include, inter alia, detecting at least four bacterial taxa in a sample obtained from the canid.

Abstract: Methods for assessing a feline's microbiome health are provided. The methods include, inter alia, determining the health of a feline's microbiome comprising quantitation four or more bacterial species and determining the relative abundance of the four or more bacterial species by comparing the abundance with a control data set, wherein an increase or decrease in the abundance can be indicative of an unhealthy microbiome.

Abstract: Methods for assessing the microbiome of a feline are provided. The methods include, inter alia, detecting one or more bacterial species in a sample obtained from the feline, comparing the one or more bacterial species to a control data set, and determining the microbiome age.

Abstract: Methods for assessing the microbiome of a canid are provided. The methods include, inter alia, detecting one or more bacterial taxa in a sample obtained from the canid, correlating the one or more bacterial taxa to a control data set, and determining the microbiome biological age.

Abstract: The presently disclosed subject matter relates to methods of determining a feline's susceptibility to developing chronic kidney disease (CKD) and to methods of preventing and/or reducing a risk of developing CKD for a feline. In certain embodiments, the biomarkers comprise creatinine, urine specific gravity or urea.

Abstract: A method for treatment of prostate cancer or benign prostate hyperplasia by combination therapy comprising administering to a patient an androgen-deprivation therapy agent and a bacteriochlorophyll derivative followed by photodynamic therapy (PDT) or vascular-targeted photodynamic therapy (VTP).

Abstract: A method for determining the biological age or pace of aging of an adult dog, said method comprising determining the levels of one or more biomarkers selected from the group consisting of (1) blood globulin levels, (2) blood total protein, (3) blood alkaline phosphatase, (4) blood platelet count, (5) blood mean corpuscular volume or (6) urine specific gravity, comparing the results with values obtained from healthy dogs of a known age and of a similar category (toy, small, medium, large or giant). Kits, systems and/or computer media for carrying out the method form further aspects of the invention.

Abstract: Methods and systems for a transportation vehicle are provided. As an example, one method includes monitoring a first set of networked devices located at a transportation vehicle and a second set of user devices that are controlled by users of the transportation vehicle; detecting a first parameter indicating a suspicious behavior by a user device; obtaining at least a second parameter associated with the user device; and correlating the first parameter and the second parameter to declare a security related event.

Abstract: Methods and systems for a transportation vehicle are provided. As an example, one method includes monitoring a first set of networked devices located at a transportation vehicle and a second set of user devices that are controlled by users of the transportation vehicle; detecting a first parameter indicating a suspicious behavior by a user device; obtaining at least a second parameter associated with the user device; and correlating the first parameter and the second parameter to declare a security related event.

Abstract: The invention concerns trading tokens, such as but not limited to, the trading of virtual trading cards. The invention also concerns a computer system (104) to facilitate the trading of tokens, a set of messages exchanged in order to trade tokens, a method of trading tokens by a token owner, and a software application to be used by the token owner to trade a token. Information relating to tokens owned by the first and second user is stored in a datastore. Using their mobile device (100), a first user (102) offers to trade a first token, and this offer is stored in the datastore (104). The server (104) then sends to the mobile communication device (112) of a second user (110) details of the offer. The second user (110) can reply by offering a second token in exchange for the first token, and this offer is also stored in the datastore and communicated to the first user (102).

Abstract: The subject invention relates to automotive head lamp assemblies with a low beam unit and a high beam unit. In an exemplary embodiment, the low beam unit and high beam unit is connected to one another by an adjuster bracket. The adjuster bracket allows for two ball studs to interact with the adjuster bracket. The first ball stud interacts with the adjuster bracket and high beam reflector so that the high beam reflector's vertical axis can be adjusted to make it parallel to the vertical axis of the low beam reflector. The second ball stud interacts with the adjuster bracket and low beam reflector so that both the low beam reflector and high beam reflector are adjusted vertically at the same time and in the same direction.

Abstract: Tissue infiltrating primer formulations and methods of using such formulations, e.g., in the dental or medical fields, are described. The formulations of the invention include an effective amount of a tissue infiltrating agent and a primer. The tissue infiltrating primer formulations provide enhanced penetration of a biomaterial into a target substrate, e.g. hard tissues, when compared to their non-tissue infiltrating primer formulation counterparts.

Abstract: There is disclosed an implant for anchoring in bone and/or fibrous connective tissue and to which a prosthesis such as a dental bridge may be connected through connecting components. The implant is of tapered design defining a wide top portion for connection to the connecting components and a tapered body comprising upper and lower regions. The lower bone-engaging region of the implant is provided with a porous surface into which bone may grow thereby anchoring the implant. The upper region of the implant has a surface suitable for bone attachment which is different from the surface of the lower region. In one embodiment, the upper portion has a larger taper angle than the rest of the implant for increased stability and stress transfer to the surrounding bone. In another embodiment, the surface of the upper region is coated with a bioreactive coating to allow direct bonding of bone and/or soft connective tissue (gingival tissue) thereby inhibiting epithelial migration apically.