Abstract: Apparatuses, systems, and methods are disclosed to produce HHO gas in a pressure-resistant container for use in an internal combustion engine to increase fuel efficiency and/or reduce emissions, for example by introducing the HHO gas to one or more air intake ports of the engine.

Abstract: A detection apparatus and method arranged to detect defects within a flexible pipe at least partially surrounded by seawater. The detection apparatus comprises a seawater electrode, an impedance monitor and a processor. The seawater electrode is arranged to be in contact with seawater surrounding at least part of a flexible pipe. The impedance monitor is arranged to measure the impedance between a metallic structural component of the flexible pipe extending at least partially along the length of the flexible pipe and the seawater electrode in response to an electrical test signal applied to the seawater electrode. The processor is arranged to determine the distance from the seawater electrode to a pipe defect electrically connecting the metallic structural component to seawater using the measured impedance.

Abstract: An embodiment of an active dosimeter system for detecting and communicating a radiation dose in real time is described that comprises a peripheral detector configured to be worn on an extremity or a head region of a user that includes a radiation sensor to detect ionizing radiation; a processor to determine a level of the ionizing radiation; and a wireless device to send a transmission comprising the detected level of the ionizing radiation; where the determination of the level of ionizing radiation and the transmission occur in real-time; and a receiver located in close proximity to the user that receives the transmission, and comprises an interface that informs the user of the detected level of the ionizing radiation.

Abstract: A detection apparatus and method arranged to detect defects within a flexible pipe at least partially surrounded by seawater. The detection apparatus comprises a seawater electrode, an impedance monitor and a processor. The seawater electrode is arranged to be in contact with seawater surrounding at least part of a flexible pipe. The impedance monitor is arranged to measure the impedance between a metallic structural component of the flexible pipe extending at least partially along the length of the flexible pipe and the seawater electrode in response to an electrical test signal applied to the seawater electrode. The processor is arranged to determine the distance from the seawater electrode to a pipe defect electrically connecting the metallic structural component to seawater using the measured impedance.

Abstract: A passive non-linear earplug can include: a tapered body having a channel extending from a wider distal end to a narrower proximal end, the tapered body having shape memory and size adapted for being received into an ear canal of a human subject; and a disk attached to the wider distal end of the tapered body, the disk having one or more holes aligned with the channel. A structural tube can be located in the channel. A handle can be attached to the tapered body and/or disk. An annular member can be coupled to the disk opposite of the tapered body, the annular member having an aperture that at least partially aligns with the channel. A tube member can be coupled to the disk opposite of the tapered body. The earplug can attenuate loud sounds while allowing normal sounds to be heard, which provides for the non-linearity.

Abstract: A first embodiment of a detection apparatus arranged to detect defects within a flexible pipe body comprises a signal generator, a receiver, a correlator and a processor. A second embodiment of a detection apparatus arranged to detect defects within a flexible pipe at least partially surrounded by seawater comprises an impedance monitor and a processor. Methods of detecting defects within a flexible pipe body, a pipeline apparatus and methods of forming pipeline apparatuses are also disclosed.

Abstract: A system includes a pulse counter having a selectable pulse counter read-out rate, a pulse counter read-out (PCRO) storage register that stores a PCRO count, and a pulse-burst counter that has a pulse-burst counter read-out rate that is faster than all but the fastest selectable pulse counter read-out rate, a subtractor module in electronic communication with the pulse counter and the PCRO that subtracts the PCRO count from the pulse counter read-out count to output an uncorrected pulse count, a selection module in electronic communication with the pulse-burst counter that selects the pulse counter read-out rate in response to input from the pulse-burst counter, a multiplexer in electronic communication with the subtractor module and the selection module, the multiplexer selecting from among at least two dead-time correction transforms, the transform corresponding to the selected pulse counter read-out rate, and a control-and-readout module that outputs a dead-time corrected pulse rate.

Abstract: A first embodiment of a detection apparatus arranged to detect defects within a flexible pipe body comprises a signal generator, a receiver, a correlator and a processor. A second embodiment of a detection apparatus arranged to detect defects within a flexible pipe at least partially surrounded by seawater comprises an impedance monitor and a processor. Methods of detecting defects within a flexible pipe body, a pipeline apparatus and methods of forming pipeline apparatuses are also disclosed.

Abstract: HHO gas is produced and stored for use by an internal combustion engine in a pressure-resistant electrolysis cell containing graphene electrodes.

Abstract: HHO gas is produced and stored in a pressure-resistant electrolysis cell having an electrolysis zone and a gas storage zone.

Abstract: An HHO gas second fuel is produced in a pressure-resistant container and distributed at a low volumetric rate at multiple locations about the internal combustion engine.

Abstract: A cell-based biosensor array includes a base plate having a plurality of substantially transparent areas. The cell-based biosensor array also includes a flexible substrate coupled to the base plate and having disposed thereon a plurality of electrode sets, a plurality of terminal contacts, and a plurality of conductive traces. Each electrode set is disposed proximate a respective one of the substantially transparent areas, and each electrode set includes at least one electrode configured to detect an electric signal. Each terminal contact is associated with a respective one of the at least one electrode and disposed proximate a perimeter of the flexible substrate. Each conductive trace is electrically coupling a respective at least one electrode to the corresponding terminal contact. A first portion of flexible substrate including the electrode sets is disposed on a first surface of the base plate.

Abstract: An energy storage pack includes a coolant inlet manifold, a coolant outlet manifold, and a plurality of thermal-exchange tubes extending between the coolant inlet manifold and the coolant outlet manifold to exchange heat between coolant passing through the plurality of thermal-exchange tubes and a plurality of battery cells mounted adjacent to and among the plurality of thermal-exchange tubes within the energy storage pack. In one embodiment, at least one of coolant inlet manifold and the coolant outlet manifold includes a plurality of thermal-exchange tube terminating structures and a plurality of hose segments intercoupling the plurality of thermal-exchange tube terminating structures. The energy storage pack may further include a coolant inlet opening located on the coolant inlet manifold and a coolant outlet opening located on the coolant outlet manifold.

Abstract: A device, method, and system are provided for monitoring the delivery of fluids through a drip chamber. The device includes an electromagnetic radiation (EMR) source and an EMR detector. A device body is employed to position the source and detector about the drip chamber so that the source and detector define an optical path across the drip chamber. A processor device is employed to detect fluid drops from differences between detector signal values separated by a lag time. The flow rate is determined from a drip factor and the detection of multiple drops. In the context of delivering intravenous (IV) fluids, a battery powered handheld monitoring device that includes the source, detector, device body, and processor device may be affixed to a drip chamber included in an infusion set. The device includes a user interface, including buttons, a display, and an audio speaker, for the input and output of information.

Abstract: The present invention is directed to an implantable drug depot useful for reducing, preventing or treating post-operative pain in a patient in need of such treatment, the implantable drug depot comprising a therapeutically effective amount of clonidine or pharmaceutically acceptable salt thereof and a polymer; wherein the depot is implantable at a site beneath the skin to reduce, prevent or treat post-operative pain, and the depot is capable of releasing (i) about 5% to about 45% of the clonidine or pharmaceutically acceptable salt thereof relative to a total amount of the clonidine or pharmaceutically acceptable salt thereof loaded in the drug depot over a first period of up to 48 hours and (ii) about 55% to about 95% of the clonidine or pharmaceutically acceptable salt thereof relative to a total amount of the clonidine or pharmaceutically acceptable salt thereof loaded in the drug depot over a subsequent period of at least 3 days.

Abstract: Medical devices and methods including polymers having biologically active agents therein are disclosed. The medical devices can be useful as implantable devices such as orthopedic implants.

Abstract: Effective treatments of pain for extended periods of time are provided. Through the administration of an effective amount of clonidine at or near a target site, one can relieve pain caused by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discogenic back pain and joint pain, as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least three days. In some embodiments, the relief can be for at least twenty-five days, at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.

Abstract: Apparatuses, systems, and methods are disclosed to produce HHO gas in a pressure-resistant container for use in an internal combustion engine to increase fuel efficiency and/or reduce emissions, for example by introducing the HHO gas to one or more air intake ports of the engine.

Abstract: An embodiment of an active dosimeter system for detecting and communicating a radiation dose in real time is described that comprises a peripheral detector configured to be worn on an extremity or a head region of a user that includes a radiation sensor to detect ionizing radiation; a processor to determine a level of the ionizing radiation; and a wireless device to send a transmission comprising the detected level of the ionizing radiation; where the determination of the level of ionizing radiation and the transmission occur in real-time; and a receiver located in close proximity to the user that receives the transmission, and comprises an interface that informs the user of the detected level of the ionizing radiation.

Abstract: A system includes a pulse counter having a selectable pulse counter read-out rate, a pulse counter read-out (PCRO) storage register that stores a PCRO count, and a pulse-burst counter that has a pulse-burst counter read-out rate that is faster than all but the fastest selectable pulse counter read-out rate, a subtractor module in electronic communication with the pulse counter and the PCRO that subtracts the PCRO count from the pulse counter read-out count to output an uncorrected pulse count, a selection module in electronic communication with the pulse-burst counter that selects the pulse counter read-out rate in response to input from the pulse-burst counter, a multiplexer in electronic communication with the subtractor module and the selection module, the multiplexer selecting from among at least two dead-time correction transforms, the transform corresponding to the selected pulse counter read-out rate, and a control-and-readout module that outputs a dead-time corrected pulse rate.