Patents by Inventor Phillip Gottlieb

Phillip Gottlieb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mechanically activated channel blocker
    Patent number: 7259145
    Abstract: The present invention discloses a peptide of SEQ ID NO:1 and its variants that blocks stretch-activated ion channels. All amino acids in this peptide are D-amino acids. The peptide, designated as D-GsMTx4, is an enantiomer of a peptide GsMTX-4 present in the venom of the spider Grammostola spatulata. The present invention also discloses a method for inhibition of stretch activated ion channels in a cell. This peptide can be used for the treatment of cardiac arrhythmias and other pathologies that involve alterations in mechanical stress.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: August 21, 2007
    Assignee: The Research Foundation of State University of New York
    Inventors: Frederick Sachs, Thomas Suchyna, Phillip Gottlieb
  • Mechanically activated channel blocker
    Publication number: 20060014691
    Abstract: The present invention discloses a peptide of SEQ ID NO:1 and its variants that blocks stretch-activated ion channels. All amino acids in this peptide are D-amino acids. The peptide, designated as D-GsMTx4, is an enantiomer of a peptide GsMTX-4 present in the venom of the spider Grammostola spatulata. The present invention also discloses a method for inhibition of stretch activated ion channels in a cell. This peptide can be used for the treatment of cardiac arrhythmias and other pathologies that involve alteartions in mechanical stress.
    Type: Application
    Filed: July 7, 2005
    Publication date: January 19, 2006
    Inventors: Frederick Sachs, Thomas Suchyna, Phillip Gottlieb