Patents by Inventor Phillip Holliger

Phillip Holliger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8435775
    Abstract: The present invention relates to an engineered polymerase with an expanded substrate range characterized in that the polymerase is capable of incorporating an enhanced occurrence of detection agent-labeled nucleotide analogue into nucleic acid synthesized by that engineered polymerase as compared with the wild type polymerase from which it is derived.
    Type: Grant
    Filed: August 24, 2007
    Date of Patent: May 7, 2013
    Assignee: Medical Research Council
    Inventors: Phillip Holliger, Nicola Ramsay, Ann-Sofie Jemth
  • Publication number: 20120184011
    Abstract: An emulsion is useful in allowing a wide variety of gene products to be expressed via eukaryotic in vitro expression. The emulsion comprises a silicone based surfactant, a hydrophobic phase and a hydrophilic phase; wherein the hydrophilic phase comprises a plurality of compartments containing a functional in vitro eukaryotic expression system.
    Type: Application
    Filed: February 29, 2012
    Publication date: July 19, 2012
    Inventors: Phillip Holliger, Farid Ghadessy
  • Patent number: 8153402
    Abstract: An emulsion is useful in allowing a wide variety of gene products to be expressed via eukaryotic in vitro expression. The emulsion comprises a silicone based surfactant, a hydrophobic phase and a hydrophilic phase; wherein the hydrophilic phase comprises a plurality of compartments containing a functional in vitro eukaryotic expression system.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: April 10, 2012
    Assignee: Medical Research Council
    Inventors: Phillip Holliger, Farid Ghadessy
  • Publication number: 20100159592
    Abstract: An emulsion is useful in allowing a wide variety of gene products to be expressed via eukaryotic in vitro expression. The emulsion comprises a silicone based surfactant, a hydrophobic phase and a hydrophilic phase; wherein the hydrophilic phase comprises a plurality of compartments containing a functional in vitro eukaryotic expression system.
    Type: Application
    Filed: October 6, 2009
    Publication date: June 24, 2010
    Inventors: Phillip Holliger, Farid Ghadessy
  • Publication number: 20100035767
    Abstract: The present invention relates to an engineered polymerase with an expanded substrate range characterized in that the polymerase is capable of incorporating an enhanced occurrence of detection agent-labeled nucleotide analogue into nucleic acid synthesized by that engineered polymerase as compared with the wild type polymerase from which it is derived.
    Type: Application
    Filed: August 24, 2007
    Publication date: February 11, 2010
    Applicant: Medical Research Council
    Inventors: Phillip Holliger, Nicola Ramsay, Ann-Sofie Jemth
  • Patent number: 7622280
    Abstract: An emulsion is useful in allowing a wide variety of gene products to be expressed via eukaryotic in vitro expression. The emulsion comprises a silicone based surfactant, a hydrophobic phase and a hydrophilic phase; wherein the hydrophilic phase comprises a plurality of compartments containing a functional in vitro eukaryotic expression system.
    Type: Grant
    Filed: June 11, 2004
    Date of Patent: November 24, 2009
    Assignee: 454 Life Sciences Corporation
    Inventors: Phillip Holliger, Farid Ghadessy
  • Patent number: 7429467
    Abstract: An emulsion is useful in allowing a wide variety of gene products to be expressed via eukaryotic in vitro expression. The emulsion comprises a silicone based surfactant, a hydrophobic phase and a hydrophilic phase; wherein the hydrophilic phase comprises a plurality of compartments containing a functional in vitro eukaryotic expression system.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: September 30, 2008
    Assignee: Medical Research Council
    Inventors: Phillip Holliger, Farid Ghadessy
  • Publication number: 20080187968
    Abstract: An emulsion is useful in allowing a wide variety of gene products to be expressed via eukaryotic in vitro expression. The emulsion comprises a silicone based surfactant, a hydrophobic phase and a hydrophilic phase; wherein the hydrophilic phase comprises a plurality of compartments containing a functional in vitro eukaryotic expression system.
    Type: Application
    Filed: March 28, 2008
    Publication date: August 7, 2008
    Inventors: Phillip Holliger, Farid Ghadessy
  • Publication number: 20050064460
    Abstract: An emulsion is useful in allowing a wide variety of gene products to be expressed via eukaryotic in vitro expression. The emulsion comprises a silicone based surfactant, a hydrophobic phase and a hydrophilic phase; wherein the hydrophilic phase comprises a plurality of compartments containing a functional in vitro eukaryotic expression system.
    Type: Application
    Filed: June 11, 2004
    Publication date: March 24, 2005
    Inventors: Phillip Holliger, Farid Ghadessy
  • Publication number: 20040253731
    Abstract: An emulsion is useful in allowing a wide variety of gene products to be expressed via eukaryotic in vitro expression. The emulsion comprises a silicone based surfactant, a hydrophobic phase and a hydrophilic phase; wherein the hydrophilic phase comprises a plurality of compartments containing a functional in vitro eukaryotic expression system.
    Type: Application
    Filed: May 13, 2004
    Publication date: December 16, 2004
    Applicant: Medical Research Council
    Inventors: Phillip Holliger, Farid Ghadessy