Patents by Inventor Phillip J. Sharp

Phillip J. Sharp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PLASMA KALLIKREIN INHIBITORS
    Publication number: 20250099478
    Abstract: The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age-related macular degeneration, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. The compounds are selective inhibitors of plasma kallikrein.
    Type: Application
    Filed: January 23, 2023
    Publication date: March 27, 2025
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Anthony K. Ogawa, Christopher J. Sinz, Alan C. Cheng, Ying-Duo Gao, Song Yang, Jianming Bao, Rohan Rajiv Merchant, Natalija Cernaka, Phillip Patrick Sharp, Jovan Alexander Lopez, Dong Xiao, Haiqun Tang, Maoqun Tian, Mihir B. Mandal, Jiafang He
  • Haemonchus contortus vaccine
    Patent number: 5525508
    Abstract: A substantially purified antigen derived from a first species of parasitic nematodes, which antigen is capable of providing protection to a host from parasitism by a second nematode species, which may be the same as or different from the first nematode species, following vaccination of the host with the antigen, characterized in that the antigen is proteinaceous, has a pI between 3.8 and 4.4, can be bound by lentil lectin and Helix promatia lectin and has a molecular weight of approximately 45 kD as determined by SDS-PAGE.
    Type: Grant
    Filed: October 6, 1992
    Date of Patent: June 11, 1996
    Assignees: Biotech Australia Pty Limited, Commonwealth and Industrial Research Organization
    Inventors: Phillip J. Sharp, Barry M. Wagland, Gary S. Cobon