Patents by Inventor Phillip L. Lowrey

Phillip L. Lowrey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Clock gene and methods of use thereof
    Patent number: 6476188
    Abstract: The present invention discloses the identity of the first enzyme that has been demonstrated to be involved in maintaining circadian rhythms. This enzyme, the Drosophila DOUBLETIME protein is also shown to be an ortholog of human casein kinase-1&egr;. In addition, a variant of this enzyme is shown to be cause of the hamster tau mutant phenotype. Thus the present invention also relates to variants of DOUBLETIME, and their nucleic acid and amino acid sequences. The present invention further provides methods of using these variants in drug assays and diagnostics.
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: November 5, 2002
    Assignees: The Rockefeller University, Northwestern University
    Inventors: Michael W. Young, Brian Kloss, Justin Blau, Jeffrey Price, Joseph S. Takahashi, Phillip L. Lowrey