Patents by Inventor Phillip Low

Phillip Low has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250017976
    Abstract: This document provides methods and materials for treating multiple system atrophy. For example, methods and materials for using autologous mesenchymal stem cells (e.g., adipose derived mesenchymal stem cells) to treat multiple system atrophy are provided.
    Type: Application
    Filed: September 27, 2024
    Publication date: January 16, 2025
    Inventors: Wolfgang Singer, Phillip Low
  • Patent number: 12133869
    Abstract: This document provides methods and materials for treating multiple system atrophy. For example, methods and materials for using autologous mesenchymal stem cells (e.g., adipose derived mesenchymal stem cells) to treat multiple system atrophy are provided.
    Type: Grant
    Filed: June 23, 2023
    Date of Patent: November 5, 2024
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Wolfgang Singer, Phillip Low
  • Publication number: 20240100097
    Abstract: This document provides methods and materials for treating multiple system atrophy. For example, methods and materials for using autologous mesenchymal stem cells (e.g., adipose derived mesenchymal stem cells) to treat multiple system atrophy are provided.
    Type: Application
    Filed: June 23, 2023
    Publication date: March 28, 2024
    Inventors: Wolfgang Singer, Phillip Low
  • Patent number: 11723928
    Abstract: This document provides methods and materials for treating multiple system atrophy. For example, methods and materials for using autologous mesenchymal stem cells (e.g., adipose derived mesenchymal stem cells) to treat multiple system atrophy are provided.
    Type: Grant
    Filed: August 12, 2022
    Date of Patent: August 15, 2023
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Wolfgang Singer, Phillip Low
  • Publication number: 20230075604
    Abstract: This document provides methods and materials for treating multiple system atrophy. For example, methods and materials for using autologous mesenchymal stem cells (e.g., adipose derived mesenchymal stem cells) to treat multiple system atrophy are provided.
    Type: Application
    Filed: August 12, 2022
    Publication date: March 9, 2023
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Wolfgang Singer, Phillip Low
  • Patent number: 11426431
    Abstract: This document provides methods and materials for treating multiple system atrophy in a mammal. Specifically, the methods comprises intrathecally administering to the mammal a composition comprising autologous mesenchymal stem cells (e.g. adipose deprived mesenchymal stem cells) to treat multiple system atrophy. Further disclosed is the composition comprising from about 5×10(6) to about 5×10(8) autologous mesenchymal stem cells.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: August 30, 2022
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Wolfgang Singer, Phillip Low
  • Publication number: 20220193672
    Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.
    Type: Application
    Filed: February 10, 2022
    Publication date: June 23, 2022
    Inventors: Phillip Lowe, Steven Alexander Keatch, Brian McGuigan
  • Patent number: 11278886
    Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: March 22, 2022
    Assignee: LumiraDx UK Ltd.
    Inventors: Phillip Lowe, Steven Alexander Keatch, Brian McGuigan
  • Patent number: 10509032
    Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to trans-port an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: December 17, 2019
    Assignee: ALERE SWITZERLAND GMBH
    Inventors: Phillip Lowe, Steven Alexander Keatch, Steven Howell, Claus Marquordt, Ruth Polwart, Alan Kenneth Thomson
  • Patent number: 10376881
    Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.
    Type: Grant
    Filed: September 7, 2011
    Date of Patent: August 13, 2019
    Assignee: LumiraDx UK Ltd.
    Inventors: Phillip Lowe, Steven Alexander Keatch, Brian McGuigan
  • Patent number: 10261077
    Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: April 16, 2019
    Assignee: LUMIRADX UK LTD
    Inventors: Phillip Lowe, Steven Alexander Keatch, Brian McGuigan
  • Publication number: 20180161374
    Abstract: This document provides methods and materials for treating multiple system atrophy in a mammal. Specifically, the methods comprises intrathecally administering to the mammal a composition comprising autologous mesenchymal stem cells (e.g. adipose deprived mesenchymal stem cells) to treat multiple system atrophy. Further disclosed is the composition comprising from about 5×10(6) to about 5×10(8) autologous mesenchymal stem cells.
    Type: Application
    Filed: June 15, 2016
    Publication date: June 14, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Wolfgang Singer, Phillip Low
  • Patent number: 9919313
    Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: March 20, 2018
    Assignee: LumiraDx UK Ltd.
    Inventors: Phillip Lowe, Steven A. Keatch, Brian McGuigan
  • Publication number: 20180059105
    Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to trans-port an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.
    Type: Application
    Filed: February 27, 2017
    Publication date: March 1, 2018
    Applicant: INVERNESS MEDICAL SWITZERLAND GMBH
    Inventors: Phillip Lowe, Steven Alexander Keatch, Steven Howell, Claus Marquordt, Ruth Polwart, Alan Kenneth Thomson
  • Patent number: 9618506
    Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: April 11, 2017
    Assignee: INVERNESS MEDICAL SWITZERLAND GMBH
    Inventors: Phillip Lowe, Steven Alexander Keatch, Steven Howell, Claus Marquordt, Ruth Polwart, Alan Kenneth Thomson
  • Publication number: 20170080420
    Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.
    Type: Application
    Filed: December 1, 2016
    Publication date: March 23, 2017
    Inventors: Phillip Lowe, Steven A. Keatch, Brian McGuigan
  • Patent number: 9341620
    Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.
    Type: Grant
    Filed: February 7, 2012
    Date of Patent: May 17, 2016
    Assignee: Multi-Sense Technologies Limited
    Inventors: Phillip Lowe, Steven Alexander Keatch, Brian McGuigan
  • Patent number: 9063132
    Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid:liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.
    Type: Grant
    Filed: April 2, 2010
    Date of Patent: June 23, 2015
    Assignee: INVERNESS MEDICAL SWITZERLAND GMBH
    Inventors: John William Dilleen, Phillip Lowe, Ruth Polwart, Jennifer Hay, Claus Marquordt, Steven Alexander Keatch, Steven Howell, Alan Thomson
  • Patent number: D912843
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: March 9, 2021
    Assignee: LumiraDx UK Ltd
    Inventors: David Lang, Michael Flett, Alex Driver, Benjamin Cox, Iain Deane, Phillip Lowe, Steven Keatch, Brian McGuigan, Alexander Reid
  • Patent number: D968642
    Type: Grant
    Filed: February 4, 2021
    Date of Patent: November 1, 2022
    Assignee: LumiraDx UK Ltd
    Inventors: David Lang, Michael Flett, Alex Driver, Benjamin Cox, Iain Deane, Phillip Lowe, Steven Keatch, Brian McGuigan, Alexander Reid