Patents by Inventor Phillip Lowe
Phillip Lowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220193672Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.Type: ApplicationFiled: February 10, 2022Publication date: June 23, 2022Inventors: Phillip Lowe, Steven Alexander Keatch, Brian McGuigan
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Patent number: 11278886Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.Type: GrantFiled: May 20, 2019Date of Patent: March 22, 2022Assignee: LumiraDx UK Ltd.Inventors: Phillip Lowe, Steven Alexander Keatch, Brian McGuigan
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Patent number: 10509032Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to trans-port an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.Type: GrantFiled: February 27, 2017Date of Patent: December 17, 2019Assignee: ALERE SWITZERLAND GMBHInventors: Phillip Lowe, Steven Alexander Keatch, Steven Howell, Claus Marquordt, Ruth Polwart, Alan Kenneth Thomson
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Patent number: 10376881Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.Type: GrantFiled: September 7, 2011Date of Patent: August 13, 2019Assignee: LumiraDx UK Ltd.Inventors: Phillip Lowe, Steven Alexander Keatch, Brian McGuigan
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Patent number: 10261077Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.Type: GrantFiled: May 16, 2016Date of Patent: April 16, 2019Assignee: LUMIRADX UK LTDInventors: Phillip Lowe, Steven Alexander Keatch, Brian McGuigan
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Patent number: 9919313Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.Type: GrantFiled: December 1, 2016Date of Patent: March 20, 2018Assignee: LumiraDx UK Ltd.Inventors: Phillip Lowe, Steven A. Keatch, Brian McGuigan
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Publication number: 20180059105Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to trans-port an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.Type: ApplicationFiled: February 27, 2017Publication date: March 1, 2018Applicant: INVERNESS MEDICAL SWITZERLAND GMBHInventors: Phillip Lowe, Steven Alexander Keatch, Steven Howell, Claus Marquordt, Ruth Polwart, Alan Kenneth Thomson
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Patent number: 9618506Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.Type: GrantFiled: March 29, 2007Date of Patent: April 11, 2017Assignee: INVERNESS MEDICAL SWITZERLAND GMBHInventors: Phillip Lowe, Steven Alexander Keatch, Steven Howell, Claus Marquordt, Ruth Polwart, Alan Kenneth Thomson
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Publication number: 20170080420Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.Type: ApplicationFiled: December 1, 2016Publication date: March 23, 2017Inventors: Phillip Lowe, Steven A. Keatch, Brian McGuigan
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Publication number: 20160320374Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.Type: ApplicationFiled: May 16, 2016Publication date: November 3, 2016Inventors: Phillip LOWE, Steven Alexander KEATCH, Brian McGUIGAN
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Patent number: 9341620Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.Type: GrantFiled: February 7, 2012Date of Patent: May 17, 2016Assignee: Multi-Sense Technologies LimitedInventors: Phillip Lowe, Steven Alexander Keatch, Brian McGuigan
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Patent number: 9063132Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid:liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.Type: GrantFiled: April 2, 2010Date of Patent: June 23, 2015Assignee: INVERNESS MEDICAL SWITZERLAND GMBHInventors: John William Dilleen, Phillip Lowe, Ruth Polwart, Jennifer Hay, Claus Marquordt, Steven Alexander Keatch, Steven Howell, Alan Thomson
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Publication number: 20140017709Abstract: A subtractive corrective assay device and methodology, whereby ail required binding and label detection reagents are initially located within the detection zone. Application of a magnetic field is used to selectively remove bound label from the detection zone by means of paramagnetic particles. The relationship between measured label concentration before and after the application of a magnetic field within the detection zone is used to accurately measure analyte concentration within the sample.Type: ApplicationFiled: February 7, 2012Publication date: January 16, 2014Applicant: MULTI-SENSE TECHNOLOGIES LIMITEDInventors: Phillip Lowe, Steven Alexander Keatch, Brian Mcguigan
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Publication number: 20130309778Abstract: The present invention relates to a microfluidic based assay system, comprising a disposable assay cartridge and associated reading device, as well as the individual components themselves. The present invention also relates to methods of conducting assays, using the cartridge and device of the invention, as well as kits for conducting assays.Type: ApplicationFiled: September 7, 2011Publication date: November 21, 2013Applicant: MULTI-SENSE TECHNOLOGIES LIMITEDInventors: Phillip Lowe, Steven Alexander Keatch, Brian McGuigan
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Publication number: 20110053289Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to trans-port an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.Type: ApplicationFiled: March 29, 2007Publication date: March 3, 2011Applicant: INVERNESS MEDICAL SWITZERLAND GMBHInventors: Phillip Lowe, Steven Alexander Keatch, Steven Howell, Claus Marquordt, Ruth Polwart, Alan Kenneth Thomson
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Publication number: 20110008813Abstract: An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid:liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.Type: ApplicationFiled: April 2, 2010Publication date: January 13, 2011Applicant: Inverness Medical Switzerland GMBHInventors: John William Dilleen, Phillip Lowe, Ruth Polwart, Jennifer Hay, Claus Marquordt, Steven Alexander Keatch, Steven Howell, Alan Thompson
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Publication number: 20100015728Abstract: A method for detecting an analyte can include binding an analyte with a first reagent which is associated with a magnetic particle, allowing analyte to interact with an excess amount of a second reagent capable of interacting with the analyte, and magnetically separating a portion of analyte-bound second reagent from excess second reagent. After the magnetic separation, the interaction of the analyte and the second reagent can be disrupted to produce a detectable form of the second reagent, which can be detected. A device and system suited to performing the method are also described.Type: ApplicationFiled: December 19, 2007Publication date: January 21, 2010Applicant: IVERNESS MEDICAL SWITZERLAND GMBHInventors: John William Dilleen, Phillip Lowe, Andrew Gill
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Publication number: 20090130771Abstract: An assay device includes a first reagent including a magnetic particle and a second reagent including detectable component. The first and second reagent can each independently bind to an analyte in a sample. Applying a magnetic field can selectively concentrate the detectable component in a detection zone, where a detectable change ca be measured and related to the amount of analyte in the sample.Type: ApplicationFiled: July 19, 2006Publication date: May 21, 2009Applicant: Inverness Medical Switzerland GMBHInventors: Oliver William Hardwicke Davies, David Kinniburgh Lang, John William Dilleen, Phillip Lowe, Steven Howell, Christopher John Slevin
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Patent number: D912843Type: GrantFiled: May 6, 2019Date of Patent: March 9, 2021Assignee: LumiraDx UK LtdInventors: David Lang, Michael Flett, Alex Driver, Benjamin Cox, Iain Deane, Phillip Lowe, Steven Keatch, Brian McGuigan, Alexander Reid
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Patent number: D968642Type: GrantFiled: February 4, 2021Date of Patent: November 1, 2022Assignee: LumiraDx UK LtdInventors: David Lang, Michael Flett, Alex Driver, Benjamin Cox, Iain Deane, Phillip Lowe, Steven Keatch, Brian McGuigan, Alexander Reid