Patents by Inventor Phillip Markham

Phillip Markham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Temperature sensitive vaccine strain of and uses thereof
    Patent number: 8524252
    Abstract: The present invention relates to a Mycoplasma hyopneumoniae vaccine strain comprising a mutation in at least one of the genes listed or as deposited with the National Measurements Institute (Australia) under accession number NM04/41259, which strain is temperature sensitive and attenuated, a vaccine comprising such strains and methods and uses thereof.
    Type: Grant
    Filed: May 19, 2010
    Date of Patent: September 3, 2013
    Assignees: Bioproperties Pty Ltd., The University of Melbourne
    Inventors: Rima Youil, Youssef Abs El-Osta, Glenn Browning, Phillip Markham
  • TEMPERATURE SENSITIVE VACCINE STRAIN OF MYCOPLASMA HYOPNEUMONIAE AND USES THEREOF
    Publication number: 20120135040
    Abstract: The present invention relates to a Mycoplasma hyopneumoniae vaccine strain comprising a mutation in at least one of the genes listed or as deposited with the National Measurements Institute (Australia) under accession number NM04/41259, which strain is temperature sensitive and attenuated, a vaccine comprising such strains and methods and uses thereof.
    Type: Application
    Filed: May 19, 2010
    Publication date: May 31, 2012
    Inventors: Rima Youil, Youssef Abs El-Osta, Glenn Browning, Phillip Markham
  • POLYVALENT, PRIMARY HIV-1 GLYCOPROTEIN DNA VACCINES AND VACCINATION METHODS
    Publication number: 20110171258
    Abstract: Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV is disclosed. The compositions and methods described herein are for the use of a DNA composition that encodes one or more different HIV envelope glycoproteins. The DNA composition can encode an HIV Gag protein. The DNAs encoding one or more HIV proteins are a combination of different nucleic acids, such as DNA plasmids, generated from primary isolate DNA of different HIV major group genetic clades and/or different proteins. HIV protein compositions for inducing an immune response against HIV are disclosed. Methods for using the protein compositions as boosts following administration of the DNA compositions are provided.
    Type: Application
    Filed: February 3, 2011
    Publication date: July 14, 2011
    Applicants: UNIVERSITY OF MASSACHUSETTS, ADVANCED BIOSCIENCE LABORATORIES, INC.
    Inventors: Shan Lu, Shixia Wang, Ranajit Pal, Vaniambadi Kalyanaraman, Stephen Charles Whitney, Tim Keen, Balachandran Nair, Phillip Markham
  • Polyvalent, primary HIV-1 glycoprotein DNA vaccines and vaccination methods
    Patent number: 7901690
    Abstract: Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV is disclosed. The composition and methods described herein are for the use of a DNA composition that encodes one or more different HIV envelope glycoproteins. The DNA composition can encode an HIV Gag protein. The DNAs encoding one or more HIV proteins are a combination of different nucleic acids, such as DNA plasmids, generated from primary isolate DNA of different HIV major group genetic clades and/or different proteins. HIV protein compositions for inducing an immune response against HIV are disclosed. Methods fro using the protein compositions as boosts following administration of the DNA compositions are provided.
    Type: Grant
    Filed: December 3, 2003
    Date of Patent: March 8, 2011
    Assignees: University of Massachusetts, Advanced Bioscience Laboratories
    Inventors: Shan Lu, Shixia Wang, Ranajit Pal, Vaniambadi Kalyanaraman, Stephen Charles Whitney, Tim Keen, Balachandran Nair, Phillip Markham
  • Polyvalent, primary HIV-1 glycoprotein DNA vaccines and vaccination methods
    Publication number: 20040191269
    Abstract: Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV is disclosed. The compositions and methods described herein are for the use of a DNA composition that encodes one or more different HIV envelope glycoproteins. The DNA composition can encode an HIV Gag protein. The DNAs encoding one or more HIV proteins are a combination of different nucleic acids, such as DNA plasmids, generated from primary isolate DNA of different HIV major group genetic clades and/or different proteins. HIV protein compositions for inducing an immune response against HIV are disclosed. Methods for using the protein compositions as boosts following administration of the DNA compositions are provided.
    Type: Application
    Filed: December 3, 2003
    Publication date: September 30, 2004
    Inventors: Shan Lu, Shixia Wang, Ranajit Pal, Vaniambadi Kalyanaraman, Stephen Charles Whitney, Tim Keen, Balachandran Nair, Phillip Markham
  • HIV immunogenic complexes
    Publication number: 20040076636
    Abstract: The present invention is directed to a vaccine and method of neutralizing antibodies against HIV infection. The vaccine comprises a complex of gp120 covalently bonded to a fragment of CD4 or a CD4 equivalent molecule.
    Type: Application
    Filed: July 2, 2003
    Publication date: April 22, 2004
    Inventors: Ranajit Pal, Phillip Markham, Timothy Keen, Stephen Whitney, V.S. Kalyanaraman