Patents by Inventor Phillip Patten

Phillip Patten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070048775
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Application
    Filed: August 17, 2006
    Publication date: March 1, 2007
    Inventors: Stephen Cardayre, Matthew Tobin, Willem Stemmer, Jon Ness, Jeremy Minshull, Phillip Patten, Venkiteswaran Subramanian, Linda Castle, Claus Krebber, Steven Bass, Ying-Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph Affholter
  • Publication number: 20070033061
    Abstract: Business methods for the commercialization of antimicrobial and cytotoxic compounds, including antibiotics and chemotherapeutic agents, are disclosed. According to one embodiment of the invention, drugs that are found to be effective but unsafe at therapeutic dosages are rescued by way of the use of an inhibitor of DNA repair, recombination, or replication, which sensitized microorganisms and cells, thereby permitting their use at a lower and safe dosage. In another embodiment, drugs that are found to be effective but cost prohibitive are rescued by way of the use of an inhibitor of DNA repair, recombination, or replication, thereby permitting their use at lower dosages and costs. A biopharmaceutical company may then, commercialize or charge royalties on such drugs.
    Type: Application
    Filed: April 5, 2006
    Publication date: February 8, 2007
    Applicant: Achaogen, Inc.
    Inventors: Phillip Patten, J. Judice
  • Publication number: 20070031878
    Abstract: Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.
    Type: Application
    Filed: September 6, 2006
    Publication date: February 8, 2007
    Inventors: Phillip Patten, Willem Stemmer
  • Publication number: 20070026446
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Application
    Filed: August 17, 2006
    Publication date: February 1, 2007
    Inventors: Stephen del Cardayre, Matthew Tobin, Willem Stemmer, Jon Ness, Jeremy Minshull, Phillip Patten, Venkiteswaran Subramanian, Linda Castle, Claus Krebber, Steven Bass, Ying-Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph Affholter
  • Publication number: 20070025966
    Abstract: The present invention provides interferon-alpha polypeptides and conjugates, and nucleic acids encoding the polypeptides. The invention also includes compositions comprising these polypeptides, conjugates, and nucleic acids; cells containing or expressing the polypeptides, conjugates, and nucleic acids; methods of making the polypeptides, conjugates, and nucleic acids; and methods of using the polypeptides, conjugates, and nucleic acids.
    Type: Application
    Filed: September 13, 2006
    Publication date: February 1, 2007
    Applicants: MAXYGEN, INC., ROCHE PALO ALTO LLC
    Inventors: Phillip Patten, Sridhar Viswanathan, Torben Nissen, Anne Vogt, Harald Kropshofer, Ralf Schumacher, Stephan Fischer, Stefan Seeber, Adelbert Grossmann, Friederike Hesse, Andreas Schaubmar, Roberto Falkenstein, Hans Koll, Markus Dembowski
  • Publication number: 20070020235
    Abstract: The present invention provides interferon-alpha polypeptides and conjugates, and nucleic acids encoding the polypeptides. The invention also includes compositions comprising these polypeptides, conjugates, and nucleic acids; cells containing or expressing the polypeptides, conjugates, and nucleic acids; methods of making the polypeptides, conjugates, and nucleic acids; and methods of using the polypeptides, conjugates, and nucleic acids.
    Type: Application
    Filed: September 13, 2006
    Publication date: January 25, 2007
    Applicants: MAXYGEN, INC., ROCHE PALO ALTO LLC
    Inventors: Phillip Patten, Sridhar Viswanathan, Torben Nissen, Anne Vogt, Harald Kropshofer, Ralf Schumacher, Stephan Fischer, Stefan Seeber, Adelbert Grossmann, Friederike Hesse, Andreas Schaubmar, Roberto Falkenstein, Hans Koll, Markus Dembowski
  • Publication number: 20070020734
    Abstract: The present invention provides interferon-alpha polypeptides and conjugates, and nucleic acids encoding the polypeptides. The invention also includes compositions comprising these polypeptides, conjugates, and nucleic acids; cells containing or expressing the polypeptides, conjugates, and nucleic acids; methods of making the polypeptides, conjugates, and nucleic acids; and methods of using the polypeptides, conjugates, and nucleic acids.
    Type: Application
    Filed: September 13, 2006
    Publication date: January 25, 2007
    Applicants: MAXYGEN, INC., ROCHE PALO ALTO LLC
    Inventors: Phillip Patten, Sridhar Viswanathan, Torben Nissen, Anne Vogt, Harald Kropshofer, Ralf Schumacher, Stephan Fischer, Stefan Seeber, Adelbert Grossmann, Friederike Hesse, Andreas Schaubmar, Roberto Falkenstein, Hans Koll, Markus Dembowski
  • Publication number: 20070009930
    Abstract: Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.
    Type: Application
    Filed: April 14, 2006
    Publication date: January 11, 2007
    Applicant: Maxygen, Inc.
    Inventors: Phillip Patten, Willem Stemmer
  • Publication number: 20070004912
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Application
    Filed: August 16, 2006
    Publication date: January 4, 2007
    Inventors: Linda Castle, Dan Siehl, Lorraine Giver, Jeremy Minshull, Cristina Ivy, Yong Chen, Phillip Patten, Nicholas Duck
  • Patent number: 7148054
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: December 12, 2006
    Assignee: Maxygen, Inc.
    Inventors: Stephen delCardayre, Matthew Tobin, Willem P. C. Stemmer, Jon E. Ness, Jeremy Minshull, Phillip Patten, Venkiteswatan Subramanian, Linda A. Castle, Claus M. Krebber, Steve Bass, Ying-Xin Zhang, Tony Cox, Gjalt Huisman, Ling Yuan, Joseph A. Affholter
  • Publication number: 20060223143
    Abstract: Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.
    Type: Application
    Filed: November 23, 2005
    Publication date: October 5, 2006
    Applicant: Maxygen, Inc.
    Inventors: Phillip Patten, Willem Stemmer
  • Publication number: 20060218663
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Application
    Filed: May 12, 2006
    Publication date: September 28, 2006
    Applicants: Verdia, Inc., Pioneer Hi-Bred International, Inc.
    Inventors: Linda Castle, Dan Siehl, Lorraine Giver, Jeremy Minshull, Cristina Ivy, Yong Chen, Phillip Patten, Rebecca Gorton, Nicholas Duck
  • Publication number: 20060205003
    Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.
    Type: Application
    Filed: May 5, 2006
    Publication date: September 14, 2006
    Inventors: Claes Gustafsson, Sridhar Govindarajan, Robin Emig, Richard Fox, Ajoy Roy, Jeremy Minshull, S. Davis, Anthony Cox, Phillip Patten, Linda Castle, Daniel Siehl, Rebecca Gorton, Teddy Chen
  • Publication number: 20060200874
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Application
    Filed: May 12, 2006
    Publication date: September 7, 2006
    Applicants: Verdia, Inc., Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours
    Inventors: Linda Castle, Dan Siehl, Lorraine Giver, Jeremy Minshull, Christina Ivy, Yong Hong Chen, Phillip Patten, Rebecca Gorton, Nicholas Duck, Billy Fred McCutchen, Roger Kemble
  • Publication number: 20060191033
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Application
    Filed: April 17, 2006
    Publication date: August 24, 2006
    Applicants: Verdia, Inc., Pioneer Hi-Bred International, Inc.
    Inventors: Linda Castle, Dan Siehl, Lorraine Giver, Jeremy Minshull, Cristina Ivy, Yong Chen, Nicholas Duck, Phillip Patten
  • Publication number: 20060166225
    Abstract: Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.
    Type: Application
    Filed: May 24, 2005
    Publication date: July 27, 2006
    Inventors: Phillip Patten, Willem Stemmer
  • Publication number: 20060142950
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Application
    Filed: January 24, 2006
    Publication date: June 29, 2006
    Applicant: Maxygen, Inc
    Inventors: Sergey Selifonov, Willem Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip Patten, Jeremy Minshull, Lorraine Giver
  • Publication number: 20060084091
    Abstract: Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.
    Type: Application
    Filed: August 5, 2005
    Publication date: April 20, 2006
    Inventors: Phillip Patten, Willem Stemmer
  • Publication number: 20060051795
    Abstract: Methods of recombining nucleic acids, including homologous nucleic acids, are provided. Families of gene shuffling oligonucleotides and their use in recombination procedures, as well as polymerase and ligase mediated recombination methods are also provided.
    Type: Application
    Filed: August 15, 2005
    Publication date: March 9, 2006
    Applicant: Maxygen, Inc.
    Inventors: Andreas Crameri, Willem Stemmer, Jeremy Minshull, Steven Bass, Mark Welch, Jon Ness, Claes Gustafsson, Phillip Patten
  • Publication number: 20050266465
    Abstract: The present invention provides interferon-alpha polypeptides and conjugates, and nucleic acids encoding the polypeptides. The invention also includes compositions comprising these polypeptides, conjugates, and nucleic acids; cells containing or expressing the polypeptides, conjugates, and nucleic acids; methods of making the polypeptides, conjugates, and nucleic acids; and methods of using the polypeptides, conjugates, and nucleic acids.
    Type: Application
    Filed: May 18, 2005
    Publication date: December 1, 2005
    Inventors: Phillip Patten, Sridhar Viswanathan, Torben Nissen, Anne Vogt, Harald Kropshofer, Ralf Schumacher, Stephan Fischer, Stefan Seeber, Adelbert Grossmann, Friederike Hesse, Andreas Schaubmar, Roberto Falkenstein, Hans Koll, Markus Dembowski, Stephens Adam