Abstract: Methods and devices use one or more of pressure, pressure drop, increased temperature, rate of temperature increase, and inert gas to kill microbes. Utilizing a method or device, liquid is subjected to a pressure drop and heated either during and/or after the pressure drop. The liquid may be heated while in droplet phase, in a liquid volume, or both. Inert gas may be dissolved into the liquid at a pressure greater than 1 Bar. The pressure is later reduced, which causes inert gas to be released from the liquid. Other method steps and processes are also disclosed.

Abstract: A method and device are described that reduce the amount of pathogens in a liquid and/or to mitigate the growth of pathogens. Utilizing the method or device, liquid product is subjected to an 8 Bar or greater pressure drop. The liquid product is then heated to increase its temperature by at least 10° C. while it is in the droplet phase and/or after being collected into a liquid volume.

Abstract: A method and device are described that reduce the amount of pathogens in a liquid and/or to mitigate the growth of pathogens. Utilizing the method or device, liquid product is subjected to an 8 Bar or greater pressure drop. The liquid product is then heated to increase its temperature by at least 10° C. while it is in the droplet phase and/or after being collected into a liquid volume.