Abstract: A filtration assembly operable in connection with a crystal form screening workstation that provides for automated crystal form screening is disclosed. The assembly includes first and second valves, with each valve having an internal passage and first, second and third ports. A filter line is interposed between the first and second valves in fluid communication with the second port of the first valve and the second port of the second valve. A filter medium is in disposed in or at the end of the filter line and adapted to filter a drug-containing suspension flowing through the filter line. The filter medium is operable to filter fluids under both positive and negative pressure conditions.

Abstract: An automated sealing assembly for use in an automated sample collection workstation includes a lower clamping plate, an upper clamping plate movable with respect to the lower clamping plate and adapted for sealable engagement with the lower clamping plate, and a clamping drive assembly including a track plate having a track, an axle support, an axle supported by the axle support, a bracket connected to the upper clamping plate and to the axle, the bracket movably and rotatably supported in the track and pivotable about the axle, a motor, and a drive member powered by the motor and adapted to move the bracket along the track.

Abstract: An automated sample collection workstation comprises a motor actuated sealing assembly having upper (23) and lower (25) clamping plates and fixtures to which particle-containing components of a particle testing unit such as an inertial impactor are mounted. The workstation also includes a sampling module (SM) including a plurality of sampling needles (SN) movable along two axes, and a solvent flow-through system. The solvent flow-through system includes a pump and multi-position valve arrangement communicating with the sealing assembly and the sampling module. The workstation can also include a pump calibration system communicating with the solvent flow-through system.