Abstract: A method for delivering a prosthetic valve to a native annulus of a heart can include inserting a delivery apparatus into a patient's body, advancing the delivery apparatus to an implantation location within the native annulus, retracting a delivery sheath of the delivery apparatus relative to the prosthetic valve to expose the prosthetic valve from a distal end of the delivery sheath, and after the prosthetic valve is exposed from the delivery sheath, expanding the prosthetic valve from a radially compressed state to a radially expanded state by reducing axial tension on a first end and a second end of the prosthetic valve.

Abstract: A delivery apparatus for a prosthetic implant can include an elongate first shaft, a first suture guide coupled to the first shaft, an elongate second shaft, and a second suture guide coupled to the second shaft. The first shaft can extend coaxially through the second shaft and the second suture guide, the first suture guide can be disposed distal to the second suture guide, and the first suture guide and the second suture guide can be configured to be axially movable relative to each other.

Abstract: A distributed exercise weight system that includes a limb unit with a first segment and a second segment. The limb unit is configured for attachment to a limb. Each of the first segment and the second segment are configured to hold at least one weight in proximity to a corresponding part of a user's limb. The first segment is configured to be disposed closer to a user's body along the limb and the second segment is configured to be disposed farther from a user's body along the limb.

Abstract: According to one embodiment, the memory system includes a nonvolatile memory including a plurality of blocks, and a controller circuit that controls execution of a data writing process and a garbage collection process. Each of the blocks is an unit of erasure. The data writing process includes a process of writing user data into the nonvolatile memory in accordance with a request from an external member. The garbage collection process includes a process of moving valid data in at least a first block into a second block among the blocks and invalidating the valid data in the first block to be erasable. Upon receiving a data write request from the external member, the controller circuit controls a length of a waiting time to be provided before or after the data writing process within a period from receiving the write request to returning a response to the external member.

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: A delivery apparatus for a prosthetic implant can include an elongate first shaft, a first suture guide coupled to the first shaft, an elongate second shaft, and a second suture guide coupled to the second shaft. The first shaft can extend coaxially through the second shaft and the second suture guide, the first suture guide can be disposed distal to the second suture guide, and the first suture guide and the second suture guide can be configured to be axially movable relative to each other.

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula II as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: According to one embodiment, a memory system includes non-volatile memory, a block management table that stores whether data in the non-volatile memory is valid or invalid in a unit of cluster, and a controller configured to execute compaction. In the block management table, first information related to likelihood that valid data within the block is invalidated is registered for each of the blocks. The controller is configured to select a block to be a target of the compaction based on the first information and use the selected block to execute the compaction.

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined herein. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: According to one embodiment, a memory system includes non-volatile memory, a block management table that stores whether data in the non-volatile memory is valid or invalid in a unit of cluster, and a controller configured to execute compaction. In the block management table, first information related to likelihood that valid data within the block is invalidated is registered for each of the blocks. The controller is configured to select a block to be a target of the compaction based on the first information and use the selected block to execute the compaction.

Abstract: A management information generating method wherein logical and physical block addresses (BAs) of continuous addresses are associated with each other in the BA translation table. When a logical block is constructed, a value is set for a maximum number of allowable defective physical blocks. A logical block having fewer defects than the set number is set usable, and a logical block having more defects than the set number is set unusable. System logical block construction is performed to preferentially select physical blocks from a plane list including a large number of usable blocks to equalize the number of usable blocks in each plane list. It is determined whether the number of free blocks is insufficient on the basis of a first management unit and whether the storage area for the indicated capacity can be reserved on the basis of the management unit different from the first unit.

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: An adjustable resistance joint brace with a pair of pivotally interconnected semi-flexible struts compressing a rubber disc washer to impart resistance during knee, elbow, ankle and hip flexion and extension. A manually adjustable knob controls the amount of resistance by squeezing together the upper strut, a rubber disc washer in between, and the lower strut. The brace includes a sleeve for housing the struts and the brace opposes movements when the struts articulate about a transverse axis corresponding to the anatomical pivot axis of the body joint of the knee, elbow, ankle, and hip. At the pivot axis, a turn of the knob clockwise tightens the brace and a counterclockwise turn of the knob would lessen the resistance. The brace has application for dynamic sports movements, daily routine movements, rehabilitation and weightlessness strength training.

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined herein. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I as defined herein. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

Abstract: A management information generating method wherein logical and physical block addresses (BAs) of continuous addresses are associated with each other in the BA translation table. When a logical block is constructed, an allowable value is set for the number of defective physical blocks. A logical block having fewer defects than the set number is set usable, and a logical block having more defects than the set number is set unusable. System logical block construction is performed to preferentially select physical blocks from a plane list including a large number of usable blocks to equalize the number of usable blocks in each plane list. It is determined whether the number of free blocks is insufficient on the basis of a first management unit and whether the storage area for the indicated capacity can be reserved on the basis of the management unit different from the first unit.