Patents by Inventor Phung Le Ngo

Phung Le Ngo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100261741
    Abstract: The present invention is directed to quinazolinone compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.
    Type: Application
    Filed: June 28, 2010
    Publication date: October 14, 2010
    Applicant: Merck
    Inventors: James C. Barrow, Rowena V. Cube, Phung Le Ngo, Kenneth E. Rittle, Zhiqiang Yang, Steven D. Young
  • Patent number: 7745452
    Abstract: The present invention is directed to quinazolinone compounds of the formula I: wherein R1, R2, R3, X1, X2 X3 are defined herein. These compounds are antagonists of T-type calcium channels, and are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.
    Type: Grant
    Filed: March 8, 2006
    Date of Patent: June 29, 2010
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: James C. Barrow, Rowena V. Cube, Phung Le Ngo, Kenneth E. Rittle, Zhiqiang Yang, Steven D. Young
  • Publication number: 20080167329
    Abstract: The present invention is directed to quinazolinone compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.
    Type: Application
    Filed: March 8, 2006
    Publication date: July 10, 2008
    Inventors: James C. Barrow, Rowena V. Cube, Phung Le Ngo, Kenneth E. Rittle, Zhiqiang Yang, Steven D. Young