Patents by Inventor Phyllis Arthasary

Phyllis Arthasary has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chromene-containing compounds with anti-tubulin and vascular targeting activity
    Patent number: 7456214
    Abstract: Chrome compounds have been discovered which demonstrate impressive cytotoxicity as well as a remarkable ability to inhibit tubulin polymerization. Such compounds as well as related derivatives are excellent clinical candidates for the treatment of cancer in humans. In addition, certain of these ligands, as pro-drugs, may well prove to be tumor selective vascular targeting chemotherapeutic agents or to have vascular targeting activity resulting in the selective prevention and/or destruction of nonmalignant proliferating vasculature.
    Type: Grant
    Filed: May 21, 2004
    Date of Patent: November 25, 2008
    Assignees: Baylor University, OXiGENE, Inc.
    Inventors: Kevin G. Pinney, Phyllis Arthasary, Anupama Shirali, Klaus Edvardsen, David J. Chaplin
  • Chromene-containing compounds with anti-tubulin and vascular targeting activity
    Publication number: 20050245489
    Abstract: Trimethoxyphenyl substituted indole ligands have been discovered which demonstrate impressive cytotoxicity as well as a remarkable ability to inhibit tubulin polymerization. Such compounds as well as related derivatives are excellent clinical candidates for the treatment of cancer in humans. In addition, certain of these ligands, as pro-drugs, may well prove to be tumor selective vascular targeting chemotherapeutic agents or to have vascular targeting activity resulting in the selective prevention and/or destruction of nonmalignant proliferating vasculature.
    Type: Application
    Filed: May 3, 2004
    Publication date: November 3, 2005
    Inventors: Kevin Pinney, Phyllis Arthasary, Anupama Shirali, Klaus Edvardsen, David Chaplin
  • Chromene-containing compounds with anti-tubulin and vascular targeting activity
    Publication number: 20050245490
    Abstract: Trimethoxyphenyl substituted indole ligands have been discovered which demonstrate impressive cytotoxicity as well as a remarkable ability to inhibit tubulin polymerization. Such compounds as well as related derivatives are excellent clinical candidates for the treatment of cancer in humans. In addition, certain of these ligands, as pro-drugs, may well prove to be tumor selective vascular targeting chemotherapeutic agents or to have vascular targeting activity resulting in the selective prevention and/or destruction of nonmalignant proliferating vasculature.
    Type: Application
    Filed: May 21, 2004
    Publication date: November 3, 2005
    Inventors: Kevin Pinney, Phyllis Arthasary, Anupama Shirali, Klaus Edvardsen, David Chaplin