Patents by Inventor PI-CHUN HUANG

PI-CHUN HUANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240115616
    Abstract: The present disclosure provides a method for treating liver cirrhosis by using a composition including mesenchymal stem cells, extracellular vesicles produced by the mesenchymal stem cells, and growth factors. The composition of the present disclosure achieves the effect of treating liver cirrhosis through various efficacy experiments.
    Type: Application
    Filed: October 4, 2023
    Publication date: April 11, 2024
    Inventors: Po-Cheng Lin, Pi-Chun Huang, Zih-Han Hong, Ming-Hsi Chuang, Yi-Chun Lin, Chia-Hsin Lee, Chun-Hung Chen, Chao-Liang Chang, Kai-Ling Zhang
  • Publication number: 20230233613
    Abstract: The present invention provides a pharmaceutical composition for treating chronic stroke, involving injection via brain into the cranium of a patient having chronic stroke for six months or more; the pharmaceutical composition is a suspension at least comprising TS stem cells, an active synergistic component and a growth factor, wherein the expression level of CD34 and CD45 of the TS stem cells is 10% or less, and the expression level of CD90 and CD105 is 90% or more; the active synergistic component is an extracellular vesicle; the growth factor is at least one selected from the group consisting of HGF, G-CSF, Fractalkine, IP-10, EGF, IL-1?, IL-1?, IL-4, IL-5, IL-13, IFN?, TGF? and sCD40L. The present invention overcomes the limitations of previous cell therapy and provides a cell-based preparation that is clinically safe and therapeutically effective for chronic cerebral stroke.
    Type: Application
    Filed: October 11, 2022
    Publication date: July 27, 2023
    Inventors: Po-Cheng Lin, Pi-Chun Huang, Chia-Hsin Lee, Ming-Hsi Chuang, Chun-Hung Chen, Chao-Liang Chang, Kai-Ling Zhang, Yi-Chun Lin, Yu-Chen Tsai, Peggy Leh Jiunn Wong, Ruei-Yue Liang
  • Publication number: 20170296586
    Abstract: The present invention provides a pharmaceutical composition to treat cerebral atrophy associated disease. Said pharmaceutical composition comprising adipose-derived stem cells, can reverse the function of excitatory synapses in dementia patients and improve the function of memory storage area in brain.
    Type: Application
    Filed: April 4, 2017
    Publication date: October 19, 2017
    Inventors: Sheng-Tzung TSAI, Ming-Hsi CHUANG, Po-Cheng LIN, Pi-Chun HUANG
  • Publication number: 20170087191
    Abstract: The present invention provides a food supplement, which comprises: a placental extract and an oil; which would promote the proliferation of CD34+ stem cells and increase the telomerase activity to achieve rejuvenation and anti-aging.
    Type: Application
    Filed: December 8, 2016
    Publication date: March 30, 2017
    Inventors: HORNG-JYH HARN, SHINN-ZONG LIN, PO-CHENG LIN, HSIN-I WANG, PI-CHUN HUANG
  • Publication number: 20130309317
    Abstract: The present invention provides a food supplement, which comprises: a placental extract and an oil; which would promote the proliferation of CD34+ stem cells and increase the telomerase activity to achieve rejuvenation and anti-aging.
    Type: Application
    Filed: September 4, 2012
    Publication date: November 21, 2013
    Applicant: GWO XI STEM CELL APPLIED TECHNOLOGY CO. LTD.
    Inventors: HORNG-JYH HARN, SHINN-ZONG LIN, PO-CHENG LIN, HSIN-I WANG, PI-CHUN HUANG