Patents by Inventor Pia Herrmann

Pia Herrmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR PROGNOSING AND TREATING COLORECTAL CANCER
    Publication number: 20190269716
    Abstract: A combination of mismatch repair (MMR) and Metastasis Associated in Colon Cancer 1 (MACC1) gene expression status of the patient serve as a basis for risk stratification of early stage colon cancer patients. Patients with defective MMR (dMMR) status have improved survival and do not benefit from 5-fluorouracil (5-FU) therapies. In contrast, patients with a proficient MMR (pMMR) status have a higher risk of recurrence and worse survival. The pMMR patients are then further stratified on the basis of MACC1 gene expression. Patients with a pMMR status and a low MACC1 expression have a favorable prognosis similar to patients having a dMMR status, whereas patients having a pMMR status and high MACC1 expression have a less favorable prognosis.
    Type: Application
    Filed: May 14, 2019
    Publication date: September 5, 2019
    Inventors: Pia Herrmann, Katharina Ilm, Katherine F. Leith, Andrea Muranyi, Ulrich-Peter Rohr, Kandavel Shanmugam, Shalini Singh, Ulrike Stein
  • USE OF METASTASIS PROGRESSOR S100A4 TRANSCRIPTS IN BODY FLUIDS OF COLORECTAL AND GASTRIC CANCER PATIENTS
    Publication number: 20120276539
    Abstract: Transcript quantification of the metastasis progressor S100A4 is performed in body fluids. Methods, assays and kits relying on this quantification are disclosed that have diagnostic and/or prognostic applications in colorectal and gastric cancer patients.
    Type: Application
    Filed: March 19, 2010
    Publication date: November 1, 2012
    Applicant: MAX-DELBRUECK-CENTRUM FÜR MOLEKULARE MEDIZIN
    Inventors: Ulrike Stein, Pia Herrmann, Susen Burock, Peter Michael Schlag