Patents by Inventor Pia SCHU

Pia SCHU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210382044
    Abstract: A method for measuring the presence of calprotectin (S100A8/A) heterodimer in a biological sample using a particle-enhanced turbidimetric immunoassay (PETIA) based on monoclonal antibodies. The method can be adapted on automated standard analyzers and provides a reliable clinical measurement of calprotectin in faecal samples and extracts. The method is comparable to commerical two-site sandwich ELISA. The disclosed method counters spontaneous agglutination caused by calcium ions and low-molecular weight calcium-binding S100 proteins as observed with conventional PETIAs. The method can be used for measuring the presence of human calprotectin in stool, urine, serum, plasma, synovial liquid and other body liquids. Metrological traceability and high commutability with conventional immunoassays (ELISA) has been shown despite of different measurement principles used.
    Type: Application
    Filed: May 9, 2018
    Publication date: December 9, 2021
    Applicants: Immundiagnostik AG, Diasys Diagnostic Systems GmbH
    Inventors: Franz-Paul Armbruster, Matthias Grimmler, Pia Schu, Tobias Becker, Felix Walzer
  • Publication number: 20200362386
    Abstract: A method for quantitatively determining the amount of acetaminophen in a sample with greater precision, greater sensitivity and fewer interactions and fewer spectral and chemical interferences with other compounds contained in the sample. The method includes acetaminophen being hydrolyzed and the resulting p-minophenol being reacted with a compound of general formula (III) in the presence of an oxidant, wherein R1 and R2, independently of one another, are selected from H, —CH3, and —OCH3, R3 is —C2H5 and R4 is a C1-4 alkyl moiety with a terminal sulfonate group, with the proviso that at least one of R1 and R2 is —OCH3 and/or R4 additionally has at least one OH substituent, and then the amount of the compound of general formula (IV) in the reaction mixture being photometrically determined.
    Type: Application
    Filed: January 8, 2019
    Publication date: November 19, 2020
    Applicant: DiaSys Diagnostic Systems GmbH
    Inventors: Matthias GRIMMLER, Detlef THÖNGES, Pia SCHU, Carolin MENZENBACH, Laura KRECKEL