Patents by Inventor Pier Lucio Anelli

Pier Lucio Anelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the manufacturing of iodinated contrast agents
    Patent number: 5728877
    Abstract: A process for the preparation of compounds of general formula (I) ##STR1## characterized in that the corresponding derivatives of general formula (II) ##STR2## are reacted with the compounds of general formula (III) ##STR3## wherein Z is halogen atom or a reactive residue of a sulfonic acid or a --N.sup.+ (R.sub.9).sub.3 cation wherein R.sub.9 is a (C.sub.1 -C.sub.6) alkyl group andR.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 R.sub.6 R.sub.7 and R.sub.8 are as herein defined.
    Type: Grant
    Filed: July 23, 1996
    Date of Patent: March 17, 1998
    Assignee: Dibra S.p.A.
    Inventors: Pier Lucio Anelli, Marino Brocchetta, Ornella Gazzotti, Fulvio Uggeri
  • Macrocyclic chelants, their chelates and uses thereof in the diagnostic field
    Patent number: 5708166
    Abstract: This invention relates to novel compounds able to chelate paramagnetic bi- or trivalent metal ions, their chelates with said metal ions and their use as contrast agents in magnetic resonance imaging (MRI).
    Type: Grant
    Filed: January 14, 1997
    Date of Patent: January 13, 1998
    Assignee: Dibra S.p.A.
    Inventors: Fulvio Uggeri, Pier Lucio Anelli, Giuseppe Manfredi, Marino Brocchetta, Franco Fedeli
  • Biphenyl iodinated derivatives and their diagnostic use
    Patent number: 5663413
    Abstract: The invention relates to novel contrast media particularly useful for X-ray diagnostic investigations of human and animal body.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: September 2, 1997
    Assignee: Dibra S.p.A.
    Inventors: Fulvio Uggeri, Pier Lucio Anelli, Marino Brocchetta, Massimo Visigalli
  • Iodinated paramagnetic chelates, and their use as contrast agents
    Patent number: 5660814
    Abstract: Novel compounds containing a polyiodinated aromatic or heteroaromatic residue and their chelate complexes with ions of metal elements with atomic number from 20 to 31, 39, from 42 to 44, 49 and from 57 to 83, and their salts with physiologically tolerable organic and inorganic bases are useful contrast agents for preparation of diagnostic formulations to obtain images of organs and/or tissues of human and animal body through the use of nuclear magnetic resonance or X-rays or the combination of both nuclear magnetic resonance and X-rays.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: August 26, 1997
    Assignee: Dibra S.p.A.
    Inventors: Fulvio Uggeri, Pier Lucio Anelli, Franco Fedeli, Marcella Murru, Christoph De Haen
  • Paramagnetic metal icon chelates and use thereof as contrast agents in magnetic resonance imaging
    Patent number: 5649537
    Abstract: Novel paramagnetic metal ion chelates and their use as contrast agents in the diagnostic technique known as "magnetic resonance imaging" (M.R.I.) of the gastrointestinal tract and particularly of the liver, are described. The novel compounds result from the conjugation of a bile acid with a chelating agent and are capable of chelating the ions of bivalent and trivalent metals. The compounds have formula A-L-B in which A is the residue of a bile acid and derivatives of a bile acid, B is the residue of a chelating agent of a bivalent or trivalent metal ion having an atomic number of 20 to 31, 39, 42, 43, 44, 49, 57 to 83, L is a ligand between A and B.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: July 22, 1997
    Assignee: Dibra S.p.A.
    Inventors: Pier Lucio Anelli, Christoph De Haen, Luciano Lattuada, Pierfrancesco Morosini, Fulvio Uggeri