Patents by Inventor Pier Luigi Sparapani

Pier Luigi Sparapani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of substance P antagonists in the treatment of the adenocarcinomas
    Patent number: 6576638
    Abstract: It is described the use of antagonists of neuro kynin receptors (NK-1; substance P receptors) in order to establish a new drug effective in the treatment of adenocarcinomas, such antagonists being one or more substances selected among those ones having the following features: pA2>6.0 both in human and in murine tissues, etherocyclic non peptidergic structures, antiangiogenic effects experimentally demonstrated onto the genito-urinary tract rumors induced via orthotopic drafts of human tumoral cells either in the genito-urinary apparatus of either immunodeficient rats or mice, decrease of the tumoral mass on tumors of the genito-urinary tract induced by orthotopic drafts of tumoral cells onto tissues of the genito-urinary tract of either immunodeficient rats or mice.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: June 10, 2003
    Assignee: Biopolis S.p.A.
    Inventors: Pierluigi Pompei, Maurizio Massi, Massimo Nabissi, Pier Luigi Sparapani