Patents by Inventor Pier P. Lovisolo

Pier P. Lovisolo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ethers of substituted hydroxymethlypyrazines
    Patent number: 4801711
    Abstract: Alkoxy methyl pyrazine N-oxides having anti lypolytic, hypotriglyceridemic and hypocholesterolaemic properties and utility are disclosed.
    Type: Grant
    Filed: June 16, 1987
    Date of Patent: January 31, 1989
    Assignee: Farmitalia Carlo Erba S.r.l.
    Inventors: Paolo Cozzi, Antonio Pillan, Leone Bertone, Pier P. Lovisolo
  • Ethers of substituted hydroxymethylpyrazines
    Patent number: 4766214
    Abstract: The compounds of the invention have the following general formula (I) ##STR1## wherein each of the groups R, R.sub.1 and R.sub.2, which may be the same or different, represents a hydrogen atom, a C.sub.1 -C.sub.6 alkoxy or C.sub.1 -C.sub.6 alkyl group, and R.sub.3 represents a straight or branched chain, saturated or unsaturated, C.sub.1 -C.sub.8 aliphatic hydrocarbon group. The compounds are useful as antilipolytic agents.
    Type: Grant
    Filed: December 5, 1986
    Date of Patent: August 23, 1988
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Paolo Cozzi, Antonio Pillan, Leone Bertone, Pier P. Lovisolo
  • Dibenzo[b,d]thiopyran derivatives, pharmaceutical composition and use
    Patent number: 4624949
    Abstract: The invention relates to compounds having the general formula (I) ##STR1## wherein R.sub.1 is carboxy, esterified carboxy or an amide of formula ##STR2## in which R.sub.9 is hydrogen or C.sub.1 -C.sub.6 alkyl, A is C.sub.2 -C.sub.6 alkylene and R.sub.a and R.sub.b are hydrogen or C.sub.1 -C.sub.6 alkyl or R.sub.a and R.sub.b taken together with the nitrogen atom to which they are linked form a saturated, optionally substituted, heteromonocyclic ring;R.sub.2 is hydrogen or C.sub.1 -C.sub.6 alkyl;each of R.sub.3 to R.sub.8 is independently hydrogen, halogen, C.sub.1 -C.sub.6 -alkyl, C.sub.3 -C.sub.4 alkenyloxy or C.sub.1 -C.sub.6 alkoxy; and the pharmaceutically acceptable salts thereof, which are useful as immunomodulating and anti-viral agents.
    Type: Grant
    Filed: March 4, 1986
    Date of Patent: November 25, 1986
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Piero Melloni, Paolo Salvadori, Pier P. Lovisolo
  • N-imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene and indan as platelet aggregation inhibitors
    Patent number: 4588738
    Abstract: Platelet aggregation inhibiting compositions and methods of use containing compounds of the formula ##STR1## where Z completes a bond or is a ##STR2## group; one of R.sub.1 and R.sub.2 is hydroxy and the other is hydrogen or alkyl, or R.sub.1 and R.sub.2, taken together, form an oxo group; and the remaining substituents are as defined in the specification.
    Type: Grant
    Filed: June 1, 1984
    Date of Patent: May 13, 1986
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Antonio Pillan, Pier P. Lovisolo
  • Condensed cycloaliphatic derivatives of substituted pyrido[1,2-a]pyrimidines and methods of treating allergic conditions, peptic ulcers and inhibiting gastric acid secretion with them
    Patent number: 4521419
    Abstract: Compounds of the formula (1) ##STR1## wherein n is 1 or 2;R.sub.1 represents a hydrogen or a halogen atom, a C.sub.1 -C.sub.4 alkyl group, a --CN group, a --CONH.sub.2 group or a --COOR.sub.8 group, wherein R.sub.8 represents hydrogen or a C.sub.1 -C.sub.6 alkyl group, unsubstituted or substituted by di(C.sub.1 -C.sub.4) - alkylamino;each of R.sub.2, R.sub.3 and R.sub.4 independently represents a hydrogen or a halogen atom, a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy group or a C.sub.3 -C.sub.4 alkenyloxy group;A completes a bond, thereby providing a double bond or, when R.sub.1 is --COOR.sub.8 wherein R.sub.8 is as defined above, A may represent also a --CH.sub.2 -- group, thereby providing a cyclopropane ring fused to the pyrido ring;R is (a) furyl, thienyl or pyridyl; or(b) a group of formula ##STR2## wherein each of R.sub.5, R.sub.6 and R.sub.7 represents, independently, a hydrogen or a halogen atom, hydroxy, formyloxy, C.sub.2 -C.sub.8 alkanoyloxy, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.
    Type: Grant
    Filed: April 27, 1983
    Date of Patent: June 4, 1985
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Gianfederico Doria, Carlo Passarotti, Pier P. Lovisolo, Ada Buttinoni
  • N-Imidazolyl derivatives of 1,2,3,4-tetrahydro-naphthalene and indan
    Patent number: 4492707
    Abstract: Compounds of the formula ##STR1## where Z completes a bond or is a ##STR2## group; one of R.sub.1 and R.sub.2 is hydroxy and the other is hydrogen or alkyl, or R.sub.1 and R.sub.2, taken together, form an oxo group;and the remaining substituents are as defined in the specification. These compounds possess hypolipaemic properties.
    Type: Grant
    Filed: July 15, 1982
    Date of Patent: January 8, 1985
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Antonio Pillan, Pier P. Lovisolo
  • 6-Substituted 6H-dibenzo[b,d]pyran derivatives and process for their preparation
    Patent number: 4463001
    Abstract: The present invention relates to new 6-substituted 6H-dibenzo [b,d]pyran derivatives, to a process for their preparation and pharmaceutical and veterinary compositions containing them.
    Type: Grant
    Filed: October 1, 1981
    Date of Patent: July 31, 1984
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Piero Melloni, Paolo Salvadori, Pier P. Lovisolo
  • Ethers of substituted hydroxymethylpyrazines
    Patent number: 4406901
    Abstract: Ethers of substituted hydroxymethylpyrazines, such as, for instance, the compound 2-methoxymethyl-5-methylpyrazine-4-oxide. The compounds exhibit elevated lipid-lowering activity, especially anti-lipolytic activity (decrease of plasma-free fatty acids), triglyceride-lowering activity, cholesterol-lowering activity, and plasma-phospholipid-lowering activity.
    Type: Grant
    Filed: November 16, 1981
    Date of Patent: September 27, 1983
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Antonio Pillan, Leone Bertone, Pier P. Lovisolo
  • 3-(1-Imidazolyl)-derivatives of 2,3-dihydro-4H-1-benzopyran
    Patent number: 4342775
    Abstract: 3-(1-imidazolyl)-derivatives of 2,3-dihydro-4H-1-benzopyran, such as, for instance, the compound 3-(1-imidazolyl)-2,3-dihydro-4H-1-benzopyran-4-one, are disclosed, as well as method of making same, and pharmaceutical compositions containing same. Also disclosed is a method of using such compounds to inhibit blood platelet aggregation, to increase total serum HDL cholesterol, to increase the ratio between .alpha.-lipoprotein and .beta.-lipoprotein total cholesterol, and/or of reducing total serum cholesterol or serum triglycerides.
    Type: Grant
    Filed: February 12, 1981
    Date of Patent: August 3, 1982
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Nicola Mongelli, Antonio Pillan, Maria Bergamaschi, Pier P. Lovisolo
  • 2-Hydroxymethyl-pyrazine derivatives and process for their preparation
    Patent number: 4267327
    Abstract: 2-Hydroxymethyl-pyrazine derivatives are disclosed, such as, for instance, the compound 2-hydroxymethyl-5-methylpyrazine-4-oxide. The compounds exhibit an elevated lipid lowering activity, and can be used to control triglyceride and cholesterol levels.
    Type: Grant
    Filed: February 26, 1979
    Date of Patent: May 12, 1981
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Paolo Cozzi, Osvaldo Magni, Leone Bertone, Romano Angelucci, Pier P. Lovisolo