Patents by Inventor Pier Paolo Di Fiore

Pier Paolo Di Fiore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND KITS COMPRISING GENE SIGNATURES FOR STRATIFYING BREAST CANCER PATIENTS
    Publication number: 20230151428
    Abstract: The present invention relates to refined prognostic clinical tools, methods, and kits for the evaluation of risk and treatment of distant recurrence in ER+/HER2-breast cancer patients.
    Type: Application
    Filed: July 29, 2022
    Publication date: May 18, 2023
    Inventors: Pier Paolo DI FIORE, Salvatore PECE, Manuela VECCHI, Stefano CONFALONIERI
  • METHODS AND KITS FOR DETERMINING THE RISK OF BREAST CANCER RECURRENCE
    Publication number: 20230143295
    Abstract: The present invention relates to methods and kits for the evaluation of risk and treatment of distant recurrence of breast cancer in a subject. The methods and kits can comprise combining the measured expression levels of a subset of genes selected from a 20-gene signature with tumor size and nodal status to determine the risk of distant recurrence.
    Type: Application
    Filed: May 7, 2021
    Publication date: May 11, 2023
    Inventors: Pier Paolo DI FIORE, Salvatore PECE
  • Methods and kits comprising gene signatures for stratifying breast cancer patients
    Patent number: 11441191
    Abstract: The present invention relates to refined prognostic clinical tools, methods, and kits for the evaluation of risk and treatment of distant recurrence in ER+/HER2? breast cancer patients.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: September 13, 2022
    Assignees: Istituto Europeo di Oncologia S.r.l., Fondazione Istituto Firc di Oncologia Molecolare (IFOM), University of Milan
    Inventors: Pier Paolo Di Fiore, Salvatore Pece, Manuela Vecchi, Stefano Confalonieri
  • METHODS AND KITS COMPRISING GENE SIGNATURES FOR STRATIFYING BREAST CANCER PATIENTS
    Publication number: 20190161809
    Abstract: The present invention relates to refined prognostic clinical tools, methods, and kits for the evaluation of risk and treatment of distant recurrence in ER+/HER2? breast cancer patients.
    Type: Application
    Filed: June 19, 2017
    Publication date: May 30, 2019
    Inventors: Pier Paolo DI FIORE, Salvatore PECE, Manuela VECCHI, Stefano CONFALONIERI
  • METHODS FOR LUNG CANCER DETECTION
    Publication number: 20170283883
    Abstract: The disclosure describes a method for diagnosing lung cancer in a subject by detecting in a biological sample obtained from that patient a miRNA signature, the presence of which provides an earlier indication of cancer than alternative art-recognized methods, including, but not limited to, low-dose computed tomography (LDCT).
    Type: Application
    Filed: September 9, 2015
    Publication date: October 5, 2017
    Inventors: Pier Paolo Di FIORE, Fabrizio BIANCHI, Francesco NICASSIO, Matteo Jacopo Luca Nicolo MARZI, Francesca MONTANI
  • Methods for Lung Cancer Detection
    Publication number: 20160068913
    Abstract: The disclosure describes a method for diagnosing lung cancer in a subject by detecting in a biological sample obtained from that patient a miRNA signature, the presence of which provides an earlier indication of cancer than alternative art-recognized methods, including, but not limited to, low-dose computed tomography (LDCT).
    Type: Application
    Filed: September 9, 2015
    Publication date: March 10, 2016
    Inventors: Pier Paolo Di Fiore, Fabrizio Bianchi, Francesco Nicassio, Matteo Jacopo Luca Nicolo Marzi, Francesca Montani
  • Cancer markers
    Patent number: 8747867
    Abstract: The invention relates to methods of diagnosis and prognosis of cancer, and in particular NSCLC, the methods comprising determining the expression level of one or more genes. In some embodiments the invention relates to prognosis of early stage NSCLC.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: June 10, 2014
    Assignee: IFOM Fondazione Instituto Firc Di Oncologia Molecolare
    Inventors: Pier Paolo Di Fiore, Francesco Nicassio, Fabrizio Bianchi
  • Cancer markers
    Patent number: 7901876
    Abstract: The invention related to methods of diagnosis and prognosis of cancer, the methods comprising determining the level of one or more gene products. In addition, the invention relates to modulators of the gene products for use in treatment of cancer. The genes include EIA-induced genes and Numb.
    Type: Grant
    Filed: September 20, 2005
    Date of Patent: March 8, 2011
    Assignee: IFOM Fondazione Instituto FIRC di Oncologia Molecolare
    Inventors: Pier Paolo Di Fiore, Salvatore Pece
  • CANCER MARKERS
    Publication number: 20100152058
    Abstract: The invention relates to methods of diagnosis and prognosis of cancer, and in particular NSCLC, the methods comprising determining the expression level of one or more genes. In some embodiments the invention relates to prognosis of early stage NSCLC.
    Type: Application
    Filed: October 9, 2009
    Publication date: June 17, 2010
    Inventors: Pier Paolo Di Fiore, Francesco Nicassio, Fabrizio Bianchi
  • Cancer Markers
    Publication number: 20080188405
    Abstract: The invention related to methods of diagnosis and prognosis of cancer, the methods comprising determining the level of one or more gene products. In addition, the invention relates to modulators of the gene products for use in treatment of cancer. The genes include EIA-induced genes and Numb.
    Type: Application
    Filed: September 20, 2005
    Publication date: August 7, 2008
    Inventors: Pier Paolo Di Fiore, Salvatore Pece, Ian Marc Bonapace, Francesco Nicassio, Fabrizio Bianchi, Manuela Vecchi, Stefano Confalonieri