Patents by Inventor Pier Paolo Scaglioni

Pier Paolo Scaglioni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of hepatitis B replication
    Publication number: 20020035081
    Abstract: The invention features a polypeptide having a first amino acid sequence of at least 70 amino acids in length that is identical to a region of a wild type HBV core protein; and lacks a second amino acid sequence of the wild type HBV core protein, where the second sequence includes the carboxyterminal three amino acids of the wild type HBV core protein and does not exceed nine amino acids in length.
    Type: Application
    Filed: March 20, 2001
    Publication date: March 21, 2002
    Inventors: Jack R. Wands, Pier Paolo Scaglioni, Margherita Melegari
  • Inhibition of viral replication
    Patent number: 6060595
    Abstract: The invention relates to methods and compositions for inhibition of viral replication in animal cells. In particular, inhibition of viral replication in a target cell is achieved by introducing into the cell (1) a protein which can be incorporated along with wild type nucleocapsid subunits into a viral nucleocapsid assembling within the cell, and thereby renders the nucleocapsid deficient in encapsidating viral nucleic acid; or (2) a recombinant nucleic acid construct that directs overexpression of the protein.
    Type: Grant
    Filed: September 3, 1997
    Date of Patent: May 9, 2000
    Assignee: The General Hospital Corporation
    Inventors: Pier Paolo Scaglioni, Margherita Melegari, Jack R. Wands